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Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

In a first-of-its-kind study published in the March 1, 2017 edition of Molecular Therapy, researchers from the National Institute on Deafness and Other Communication Disorders and Johns Hopkins University School of Medicine showed that gene therapy was able to restore balance and hearing in genetically modified mice that mimic Usher Syndrome, a genetic condition in humans characterized by partial or total hearing loss, dizziness, and vision loss that worsens over time.

23 Mar 2017

Study compares arm measures to BMI for assessing nutritional status of leukemia survivors

Arm anthropometry is a simple method to determine if a person is overweight or obese, and because it can distinguish between fat and muscle mass, unlike body mass index (BMI), it is a valuable method for assessing muscle loss in long-term survivors of childhood cancer.

23 Mar 2017

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

A Phase I clinical trial that targeted individuals with new onset paraplegia to evaluate the safety of transplanting their own potentially neuroprotective Schwann cells into a trauma-induced spinal cord lesion showed no evidence of adverse effects after 1 year.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD.

21 Mar 2017

Researchers use Syngene’s G:BOX Chemi XRQ image analysis system in cardiac research

Syngene, a world-leading manufacturer of image analysis solutions is delighted to announce that the G:BOX Chemi XRQ high resolution, multi-application image analysis system is being successfully used at the Lithuanian University of Health Sciences Academy of Medicine to study molecular mechanisms of cardiac stem cell function which could help in developing stem cell therapies for heart repair.

From Syngene 17 Mar 2017

Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

UB research yields neural crest cells from adult skin cells without genetic modification

A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.

15 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Researchers identify new gene that can lead to sudden death among young people

Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes.

10 Mar 2017

IU study reveals new compounds with potential to boost enzyme that could protect against dementia

A study by Indiana University researchers has identified 24 compounds -- including caffeine -- with the potential to boost an enzyme in the brain shown to protect against dementia.

7 Mar 2017

New drug-like compound shows potential to treat symptoms of lupus

Lupus, a chronic autoimmune disease, has proved difficult to treat, but a new international study co-led by a Rush University Medical Center researcher suggests that a drug starting through the pipeline could ameliorate or even eliminate the symptoms in most sufferers.

7 Mar 2017

EuroPrevent 2017 to explore innovative ideas in preventive cardiology

Innovations to prevent heart disease will take centre stage at EuroPrevent 2017 in Malaga, Spain. EuroPrevent is the annual congress of the European Association of Preventive Cardiology, a registered branch of the European Society of Cardiology.

6 Mar 2017

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

An enzyme that helps break down cholesterol may also be a therapeutic target to stave off neurologic diseases, including Alzheimer's and a rare genetic disorder, according to a new study published in the Journal of Biological Chemistry.

2 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

Genetic Engineering News and Research

Inner ear gene therapy holds promise for treating patients with hearing loss and dizziness

Study compares arm measures to BMI for assessing nutritional status of leukemia survivors

Study shows safety of Schwann cell transplantation for treating subacute thoracic spinal cord injury

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

Researchers use Syngene’s G:BOX Chemi XRQ image analysis system in cardiac research

Study shows how immune cells drive heart damage in mice

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

UB research yields neural crest cells from adult skin cells without genetic modification

LJI researchers unravel molecular underpinnings of exhausted T cells

Researchers identify new gene that can lead to sudden death among young people

IU study reveals new compounds with potential to boost enzyme that could protect against dementia

New drug-like compound shows potential to treat symptoms of lupus

EuroPrevent 2017 to explore innovative ideas in preventive cardiology

Cholesterol-processing enzyme could be therapeutic target to stave off neurologic diseases

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

Study provides new insights into side effects of antipsychotics

Researchers discover rare deafness-dystonia syndrome in a family in Pakistan

MSK researchers harness power of CRISPR/Cas9 to create more-potent CAR T cells

Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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