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Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

Severe COVID-19 outcomes in breakthrough infections in patients being treated with B cell depleting therapy

Scientists evaluated the incidence and severity of breakthrough SARS-CoV-2 infections among individuals with immune-mediated inflammatory diseases undergoing B cell depleting therapy.

25 Feb 2022

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Treatment of nasopharyngeal carcinoma (NPC), a group of cancers that originate in the nose and throat, is made complicated by their unique position. Radiation therapy is often the main curative treatment for NPC. However, some patients are resistant to radiation therapy.

25 Feb 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Study uses 3D cervical organoids to show the danger of multiple infections

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models.

25 Feb 2022

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown.

25 Feb 2022

New prototype sensor aids in the rapid assessment of disease severity

Scientists have developed a prototype sensor that could help doctors rapidly measure adenosine triphosphate (ATP) and lactate levels in blood samples from patients, aiding in the rapid assessment of the severity of some diseases.

25 Feb 2022

Cell-mediated immune response among inflammatory bowel disease patients after mRNA COVID-19 vaccination

Researchers evaluated CMIR in IBD patients following immunization with two doses of COVID-19 vaccine.

25 Feb 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Health care firms were pushed to confront racism. Now some are investing in Black startups.

Marcus Whitney stands out in Nashville's $95 billion health care sector as an investor in startups. In addition to co-founding a venture capital firm, he's organized an annual health tech conference and co-founded the city's professional soccer club.

25 Feb 2022

Single Use Support brings cell & gene therapy expert Katy Spink on board

Katherine (Katy) Spink has become a member of Single Use Support’s Board of Directors. Her many years of expertise in cell & gene therapy consulting will enrich the companies’ focus on innovating solutions for advanced therapies.

From Single Use Support GmbH 25 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Pioneering technique uses a magnetic device to stimulate touch sensitive brain glial cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

24 Feb 2022

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

A Stony Brook University physician-scientist has identified that mucosal-associated invariant T (MAIT) cells, an unconventional form of immune cell, exercise several complex roles during healthy and disease states.

24 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

New stem cell model could help map out the key genomic changes during early development

Researchers from the Babraham Institute have today published their latest work in the journal Cell Stem Cell describing a new subset of human embryonic stem cells that closely resemble the cells present at the genomic 'wake up call' of the 8-cell embryo stage in humans.

24 Feb 2022

MIT chemists develop a novel way to synthesize himastatin

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

24 Feb 2022

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development.

24 Feb 2022

Cell News and Research

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Severe COVID-19 outcomes in breakthrough infections in patients being treated with B cell depleting therapy

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Study uses 3D cervical organoids to show the danger of multiple infections

Osteoblast-derived vesicles regulate the switch from bone formation to resorption via a miRNA-mediated mechanism

New prototype sensor aids in the rapid assessment of disease severity

Cell-mediated immune response among inflammatory bowel disease patients after mRNA COVID-19 vaccination

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Health care firms were pushed to confront racism. Now some are investing in Black startups.

Single Use Support brings cell & gene therapy expert Katy Spink on board

Mapping cells to understand vascular disease

Pioneering technique uses a magnetic device to stimulate touch sensitive brain glial cells

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

Melatonin as a safe and potentially life-saving treatment for COVID-19

New stem cell model could help map out the key genomic changes during early development

MIT chemists develop a novel way to synthesize himastatin

Scientists uncover new role of chromatin-modulatory enzyme during cancer development

Improve fermentation and cell culture performance with real-time gas analysis eBook

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