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Study reveals lung-brain link between smoking and neurodegeneration

The correlation between smoking and neurodegeneration is well-documented, with one study from 2011 finding heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, Alzheimer's and vascular dementia more than two decades later.

8 Apr 2026

Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

8 Apr 2026

Preconditioned skin cells enable faster and more effective wound healing

It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same.

8 Apr 2026

Sponge and sea slug partnership yields a new anticancer molecule with drug design promise

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

8 Apr 2026

Why early-onset cancers are rising and how researchers plan to stop them

Early-onset cancers are rising worldwide, and this Cell Perspective argues that cancer prevention must move beyond static risk-factor snapshots toward life-course exposure mapping, tissue-level biology, and dynamic estimates of preventability. The authors propose three linked frameworks to speed discovery of cancer causes and translate those findings into more precise prevention and interception strategies.

8 Apr 2026

Study outlines principles for using CAR immunotherapies to treat neurodegenerative diseases

A UAB research team defines the criteria that CAR immunotherapies for neurodegenerative diseases must meet to advance both conceptually and in trials, which are still at a very preliminary stage, in a review study published in the journal Trends in Pharmacological Sciences.

8 Apr 2026

Insilico Medicine nominates AI-driven drug candidate for cancer, Cushing's syndrome and obesity

The NR3C1 (nuclear receptor subfamily 3 group C member 1) gene encodes the glucocorticoid receptor (GR), a nuclear receptor vital for maintaining physiological homeostasis, and inhibition of NR3C1 could increase the sensitivity of cancer cells to standard chemotherapy, particularly in ovarian cancer.

8 Apr 2026

Study reveals how tau tangles spread from one brain region to another in Alzheimer's

Alzheimer's disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with daily functioning.

8 Apr 2026

New MRI method tracks transplanted heart stem cells for months

Researchers at the Institute of Biomedical Engineering at the University of Toronto have demonstrated a new way to monitor transplanted stem-cell-derived heart cells using magnetic resonance imaging (MRI).

8 Apr 2026

Yale researchers use zebrafish to find precision treatments for autism

In recent decades, the zebrafish has become one of the most valuable model organisms in scientific research.

8 Apr 2026

New cell atlas reveals biological links to pregnancy complications

The biological connection between a pregnant woman and her developing baby has been mapped in unprecedented detail by UC San Francisco scientists, revealing new cell types and insights into conditions such as preeclampsia, preterm birth, and miscarriage.

8 Apr 2026

Clusterin inhibition offers new hope for treating cervical gastric-type adenocarcinoma

Gastric-type adenocarcinoma (GAS) is one of the most aggressive non-human papillomavirus (HPV)-associated cervical adenocarcinomas and remains especially difficult to diagnose and treat.

8 Apr 2026

Study reveals how hyperdiploidy creates rare pre-leukemic clones in children

B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood cells, one of the most common abnormalities is the presence of cells with an excess of chromosomes (hyperdiploidy), a condition that leads to chromosomal instability.

8 Apr 2026

Future CAR therapy expands beyond T cells to treat diverse diseases

CAR-T therapy has transformed treatment for some blood cancers, with seven FDA-approved products and strong clinical responses in hematologic malignancies.

8 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Gut microbiota regulates intestinal epithelial cell function and plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

7 Apr 2026

Noninvasive urine test improves prediction of bladder cancer treatment outcomes

Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder cancer (NMIBC), in which the tumors are confined to the inner layers of the bladder.

7 Apr 2026

Neighborhood conditions linked to cellular aging and health disparities

There's a growing consensus that your zip code is a strong predictor of your health and lifespan. Now, researchers at NYU School of Global Public Health have determined that neighborhood conditions may be driving aging at the cellular level.

7 Apr 2026

RNA barcoding maps neural connections with unprecedented resolution

By tagging neurons with molecular "barcodes," researchers mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution.

7 Apr 2026