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Research findings on sweat glands have potential to improve methods for culturing skin grafts

As early humans shed the hairy coats of their closest evolutionary ancestors, they also gained a distinct feature that would prove critical to their success: a type of sweat gland that allows the body to cool down quickly. Those tiny glands are enormously useful, allowing us to live in a wide variety of climates, and enabling us to run long distances.

4 Jan 2017

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

Richard Myers, PhD, professor of neurology at Boston University School of Medicine, was recently awarded $100,000 from the Ellison Foundation for research to further study a Parkinson's disease (PD) target.

4 Jan 2017

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.

3 Jan 2017

Chemical modification improves release and availability of insulin, research shows

Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism.

3 Jan 2017

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to restimulate the immune system to recognize cancer cells and target them for destruction.

3 Jan 2017

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

ampk Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin.

3 Jan 2017

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer.

3 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

UM SOM study identifies key Zika proteins as likely suspects for damage

Until it burst onto the scene earlier this year, Zika was an obscure, little-known virus. As a result, scientists know little about how it works.

3 Jan 2017

Massive sequencing and coevolution unveils secrets of human protein interactions

Cells operate like an incredibly well-synchronized orchestra of molecular interactions among proteins. Understanding this molecular network is essential not only to understand how an organism works but also to determine the molecular mechanisms responsible for a multitude of diseases.

30 Dec 2016

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells.

30 Dec 2016

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.

30 Dec 2016

Acute stress can lead to delayed, long-term psychological trauma

Mrs. M would never forget that day. She was walking along a busy road next to the vegetable market when two goons zipped past on a bike. One man's hand shot out and grabbed the chain around her neck.

30 Dec 2016

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer.

30 Dec 2016

New active pharmaceutical ingredient may help against severe forms of testicular cancer

A new active pharmaceutical ingredient may help against severe forms of testicular cancer, which only respond inadequately to other therapies.

30 Dec 2016

New tool explains how proteins assemble into different liquid and gel-like solid states

A tool that uses light to manipulate matter inside living cells has begun to explain how proteins assemble into different liquid and gel-like solid states, a key to understanding many critical cellular operations.

30 Dec 2016

"More aggressive" nutrition improves growth and development of tiny premature babies

On New Year's Day this coming Sunday, we will once again be waiting to see whereabouts in Austria the first baby is born safe and sound to be our "New Year's Baby 2017".

30 Dec 2016

New evidence may explain how gut microorganisms affect human physiology

Researchers have found evidence that could shed new light on the complex community of trillions of microorganisms living in all our guts, and how they interact with our bodies.

30 Dec 2016

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

Advances in microscopy techniques have often triggered important discoveries in the field of neuroscience, enabling vital insights in understanding the brain and promising new treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.

29 Dec 2016

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G Protein News and Research

Research findings on sweat glands have potential to improve methods for culturing skin grafts

BUSM professor receives Ellison Foundation grant to explore new Parkinson's disease target

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

Chemical modification improves release and availability of insulin, research shows

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

TSRI researchers develop new approach to find how environmental estrogens impact public health

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

UM SOM study identifies key Zika proteins as likely suspects for damage

Massive sequencing and coevolution unveils secrets of human protein interactions

Researchers identify possible treatment targets for myelodysplasia syndromes

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Acute stress can lead to delayed, long-term psychological trauma

A new strategy to fight prostate cancer

New active pharmaceutical ingredient may help against severe forms of testicular cancer

New tool explains how proteins assemble into different liquid and gel-like solid states

"More aggressive" nutrition improves growth and development of tiny premature babies

New evidence may explain how gut microorganisms affect human physiology

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Super-resolution fluorescence microscopy sheds light on brain’s molecular mechanism

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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