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Genome-wide epigenomic screening can pinpoint thyroid disease-associated variants

Genome-wide epigenomic screening can pinpoint disease-associated variants and identify novel genetic-epigenetic interactions in autoimmune thyroid diseases, according to new data presented at the 82nd Annual Meeting of the American Thyroid Association (ATA) in Québec City, Québec, Canada.

24 Sep 2012

Maternal choline intake could essentially change fetal genetic expression into adulthood

Just as women are advised to get plenty of folic acid around the time of conception and throughout early pregnancy, new research suggests another very similar nutrient may one day deserve a spot on the obstetrician's list of recommendations.

24 Sep 2012

NCI awards Provocative Questions grant to Mount Sinai School of Medicine researchers

Two Mount Sinai School of Medicine researchers are among a select group of scientists from around the world who have been recognized by the National Cancer Institute (NCI) for their quest to answer the most pressing questions about cancer. Stuart Aaronson, MD, Professor and Chair of Oncological Sciences and Ross Cagan, PhD, Professor of Oncological Sciences at Mount Sinai, have received the NCI's new "Provocative Questions" grant, which was established to explore the important yet less obvious questions about cancer that may have been neglected in this era of significant discovery.

21 Sep 2012

Glucocorticoids can thwart androgen receptor activity and regulate fat storage

In the body's ongoing effort to maintain a healthy weight, an arsenal of cellular proteins called androgen receptors is critical for blocking fat accumulation. Now researchers reporting in the September issue of the Cell Press Journal Chemistry & Biology have discovered that naturally occurring steroids called glucocorticoids can thwart the receptors' activity, ultimately encouraging fat buildup.

21 Sep 2012

MD Anderson introduces Moon Shots Program to reduce cancer deaths

The University of Texas MD Anderson Cancer Center announces the launch of the Moon Shots Program, an unprecedented effort to dramatically accelerate the pace of converting scientific discoveries into clinical advances that reduce cancer deaths.

21 Sep 2012

Loss of IGSF1 gene function causes central hypothyroidism

Loss of function in the X-linked immunoglobulin superfamily member 1 (IGSF1) gene causes central hypothyroidism, testicular enlargement, and variable prolactin deficiency, according to data presented at the 82nd Annual Meeting of the American Thyroid Association in Québec City, Québec, Canada.

21 Sep 2012

Caltech biologists gain new insight into migrating cells

At any given moment, millions of cells are on the move in the human body, typically on their way to aid in immune response, make repairs, or provide some other benefit to the structures around them. When the migration process goes wrong, however, the results can include tumor formation and metastatic cancer. Little has been known about how cell migration actually works, but now, with the help of some tiny worms, researchers at the California Institute of Technology (Caltech) have gained new insight into this highly complex task.

21 Sep 2012

Research focuses on HER2 cancers

As scientists continue to map breast cancer's complex genetic makeup, research at Michigan State University could lead to better diagnoses and new treatment targets.

21 Sep 2012

First extensive analysis of Allen Human Brain Atlas

Scientists at the Allen Institute for Brain Science reported in the latest issue of the journal Nature that human brains share a consistent genetic blueprint and possess enormous biochemical complexity. The findings stem from the first deep and large-scale analysis of the vast data set publicly available in the Allen Human Brain Atlas.

21 Sep 2012

Systems biologist to pursue research into next-generation genome sequencing technology

Systems biologist Edward Marcotte has received a $2.5 million grant from the National Institutes of Health to pursue cutting-edge research in the area of genome sequencing technology.

21 Sep 2012

NIH announces multiple awards to UCLA Center for Autism Research and Treatment

The National Institutes of Health, recognizing UCLA's preeminence in both research and clinical care for children with autism, has announced multiple awards to the university as part of the agency's Autism Centers of Excellence (ACE) research program.

20 Sep 2012

Study finds high levels of ESBL bacteria in Danish chicken meat

Nearly half of the samples from chicken meat imported into Denmark contain ESBL bacteria and for the first time the level is almost as high in Danish chicken meat. By contrast, the occurrence in Danish pigs has decreased significantly since farmers stopped using cephalosporins for pigs.

20 Sep 2012

Tel Aviv University researcher discovers homing device that draws cancer

The process of metastasis, by which cancer cells travel from a tumor site and proliferate at other sites in the body, is a serious threat to cancer patients. According to the National Cancer Institute, most recurrences of cancer are metastases rather than "new" cancers.

20 Sep 2012

Views on obesity: Difficulty changing eating habits; Huge changes in the food marketplace

The New York Times and the Journal of the American Medical Association offer opinions on the U.S. battle against obesity.

20 Sep 2012

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide. In addition, the incidence and mortality rates of colorectal cancer are on the rise. Recently, metabolic genes have received increasing and specific attention due to their potential role in carcinogenesis.

20 Sep 2012

Genes News and Research

Genome-wide epigenomic screening can pinpoint thyroid disease-associated variants

Maternal choline intake could essentially change fetal genetic expression into adulthood

NCI awards Provocative Questions grant to Mount Sinai School of Medicine researchers

Glucocorticoids can thwart androgen receptor activity and regulate fat storage

MD Anderson introduces Moon Shots Program to reduce cancer deaths

Loss of IGSF1 gene function causes central hypothyroidism

Caltech biologists gain new insight into migrating cells

Research focuses on HER2 cancers

First extensive analysis of Allen Human Brain Atlas

Systems biologist to pursue research into next-generation genome sequencing technology

NIH announces multiple awards to UCLA Center for Autism Research and Treatment

Study finds high levels of ESBL bacteria in Danish chicken meat

Tel Aviv University researcher discovers homing device that draws cancer

Views on obesity: Difficulty changing eating habits; Huge changes in the food marketplace

RRM2 may be a facilitating factor in colorectal cancer and UV-induced DNA damage repair

Scientists identify unique molecular signature in iPSCs that show promise in regenerative medicine

Study uncovers why some HIV-positive people take long time to progress to full-blown AIDS

BGI Tech achieves whole exome sequencing analysis of total degraded DNA from FFPE samples

Study finds major reason why melanoma is largely resistant to chemotherapy

EMD Millipore announces global licensing agreement for AJ's iPS cell patent portfolio

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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