Genetic Engineering News and Research

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Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.

25 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

Switching off brain regions helps better understand link between neural circuits and behaviour

Switching off specific brain regions in a laboratory animal is an important type of experiment used to better understand how the brain works.

24 Jan 2017

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

18 Jan 2017

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.

18 Jan 2017

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease.

17 Jan 2017

S. pneumoniae uses hosts' immune defenses to spread infection, study reveals

The bacteria that cause most cases of pneumonia worldwide secrete a toxin that helps them jump from one body to the next - with help from the hosts' immune defenses. This is the finding of a study led by researchers from NYU Langone Medical Center and published online January 11 in Cell Host & Microbe.

12 Jan 2017

Mediterranean plants may become source for 'elixir of life'

The Mediterranean is a haven for lovers of crystal-clear seas and sun-kissed landscapes. Now, thanks to the work of scientists from the University of Malta and the Centre National de la Recherche Scientifique, it has the added appeal of being an actual fountain of youth.

9 Jan 2017

ATA releases new guidelines for diagnosis, treatment of thyroid disease during pregnancy and postpartum

New evidence-based recommendations from the American Thyroid Association provide guidance to clinicians in diagnosing and managing thyroid disease during pregnancy and the postpartum period.

6 Jan 2017

Researchers uncover reason for stent failure in diabetic patients with clogged arteries

People with any form of diabetes are at greater risk of developing cardiovascular conditions than people without the disease. Moreover, if they undergo an operation to open up a clogged artery by inserting a "stent" surgical tube, the artery is much more likely to clog up again.

4 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Studies in non-human primates provide more predictive results in genetic causes of blindness

Many gene therapy-based approaches are in development to combat genetic and other causes of blindness and vision loss, and much can be learned about the safety and effectiveness of these promising new therapies by studying them first in non-human primates before initiating clinical trials, as shown by the results of a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Genetic Engineering News and Research

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Switching off brain regions helps better understand link between neural circuits and behaviour

Researchers uncover how stress hormone prevents digestive enzymes from damaging pancreas

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

S. pneumoniae uses hosts' immune defenses to spread infection, study reveals

Mediterranean plants may become source for 'elixir of life'

ATA releases new guidelines for diagnosis, treatment of thyroid disease during pregnancy and postpartum

Researchers uncover reason for stent failure in diabetic patients with clogged arteries

AAV-based gene therapy to treat liver disorders advances into human testing

Studies in non-human primates provide more predictive results in genetic causes of blindness

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Making muscles burn more fat and less glucose could cause diabetes, say researchers

Scientists identify gene variants causing unrecognized developmental disorder

New TSRI study shows how Piezo2 protein plays critical role in sensing lung expansion

Scientists discover link between Huntington's disease and dysfunction of subthalamic nucleus

MedUni Vienna scientists show that addictive cravings can be detected after death

Genetic mutation may increase susceptibility to cytomegalovirus infection

Low-carbohydrate diet may help reverse inherited intellectual disability linked to Kabuki syndrome

eBook: Using iPSCs models for human disease research and drug discovery eBook

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