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The impact of SARS-CoV-2 linkage on outcomes in hospitalized children with PIMS across Canada

Researchers analyze the clinical effects and implications of SARS-CoV-2 infection in children who were hospitalized due to MIS-C.

1 Jun 2022

Inverse relationship identified between SARS-CoV-2 and influenza infections

A new study identifies the potential correlations that exist between SARS-CoV-2 and influenza infections.

1 Jun 2022

SARS-CoV-2 variation within individual hosts holds largely untapped information that may enhance the resolution of transmission inferences

Researchers assessed the variation of SARS-CoV-2 within hosts.

1 Jun 2022

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

Researchers investigated a SARS-CoV-2 outbreak among individuals who attended an overnight summer camp in Texas in June 2021.

1 Jun 2022

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

Researchers compared the performance of a highly multiplexed mass spectrometry-based commercial assay to identify SARS-CoV-2 variants.

31 May 2022

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Single-cell RNA-sequencing (scRNA-seq) shows which genes are turned on in a cell and what their level of transcription is. This allows in-depth assessment of the biology of individual cells, and detection of changes that may indicate disease.

31 May 2022

Prevalence of SARS-CoV-2 infection during Omicron BA.2/BA.2.12.1 surge in New York

Researchers surveyed a representative sample of the adult population of New York City, United States, to determine the prevalence of COVID-19.

30 May 2022

Exploring virological profiles of recently emerged SARS-CoV-2 Omicron variants

Researchers explored the virological profiles of novel SARS-CoV-2 Omicron variants.

30 May 2022

Researchers evaluate atovaquone as a COVID-19 treatment

Researchers evaluated a drug, atovaquone, for COVID-19 treatment.

30 May 2022

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

A recent study published in The Lancet Microbe described the case of a non-vaccinated female coinfected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 and BA.2 subvariants.

30 May 2022

Investigating post-COVID complaints after Delta versus Omicron variant infections

A new study discusses whether infection with the SARS-CoV-2 Omicron variant increases the risk of post-COVID complaints Delta infection.

30 May 2022

Investigating incidence and clinical features of post-acute sequelae of COVID-19 in children and adolescents

Researchers identify symptoms and systematic conditions associated with PASC in children

30 May 2022

Exploring the effect of genetic variability on COVID-19 infection and severity

Researchers demonstrated how narrow-sense heritability (h2) leads to variability in the susceptibility to COVID-19 infection and severity among different individuals.

27 May 2022

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

Researchers profiled the binding sites of the entire SARS-CoV-2 spike protein sequence.

26 May 2022

The role of pyroptosis in COVID-19

Researchers investigate the mechanisms by which SARS-CoV-2 induces NLRP3 inflammasome formation leading to pyroptosis.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

Transcription News and Research

The impact of SARS-CoV-2 linkage on outcomes in hospitalized children with PIMS across Canada

Inverse relationship identified between SARS-CoV-2 and influenza infections

SARS-CoV-2 variation within individual hosts holds largely untapped information that may enhance the resolution of transmission inferences

Study investigates an outbreak of SARS-CoV-2 among children and adults after attending an overnight summer camp

Robust and highly multiplexed assay for identification of SARS-CoV-2 variants

IOB's new scRNA-seq protocol provides a snapshot of the cell transcriptome at unprecedented resolution

Prevalence of SARS-CoV-2 infection during Omicron BA.2/BA.2.12.1 surge in New York

Exploring virological profiles of recently emerged SARS-CoV-2 Omicron variants

Researchers evaluate atovaquone as a COVID-19 treatment

Researchers report the case of a non-vaccinated patient coinfected with SARS-CoV-2 Omicron BA.1 and BA.2

Investigating post-COVID complaints after Delta versus Omicron variant infections

Investigating incidence and clinical features of post-acute sequelae of COVID-19 in children and adolescents

Exploring the effect of genetic variability on COVID-19 infection and severity

Researchers report novel interactions between the SARS-CoV-2 S protein and estrogen receptor alpha

The role of pyroptosis in COVID-19

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Study unveils the novel driver of cardiomyocyte loss

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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