Genes News and Research

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Researchers discover molecular 'switch' that controls replication, transcription of mitochondria DNA

A team of researchers led by Dmitry Temiakov, PhD, of the Rowan University School of Osteopathic Medicine (RowanSOM), has discovered a molecular 'switch' that controls replication and transcription of mitochondria DNA, a key finding that could influence the development of targeted therapies for cancer, developmental processes related to fertility and aging.

16 Feb 2015

Researchers develop novel strategy in fight against cancer

A team of researchers led by Associate Professor Caroline Lee from the Yong Loo Lin School of Medicine at the National University of Singapore, in collaboration with Associate Professor Song Jianxing of the Department of Biological Sciences at the NUS Faculty of Science, has developed a novel strategy in the fight against cancer.

15 Feb 2015

Scientists find seven new genes that can cause X-linked intellectual disability

X-linked intellectual disability is a disorder that predominantly affects men and can have highly variable clinical manifestations. Scientists at the Max Planck Institute for Molecular Genetics in Berlin have found seven new genes that can cause this genetic disease: Mutations of these genes on the X chromosome lead to various forms of intellectual disability.

15 Feb 2015

Researcher uses Gene Rank technique to capture, describe gene connectivity

Using the technique known as "Gene Rank" (GR), Dartmouth's Norris Cotton Cancer Center investigator Eugene Demidenko, PhD, captured and described a new characterization of gene connectivity in "Microarray Enriched Gene Rank," published in BioData Mining. The effective computer algorithm can be used to compare tissues across or within organisms at great speed with a simple laptop computer.

15 Feb 2015

A*STAR's GIS scientists develop new system that can predict treatment targets for cancer

In recent months, several national initiatives for personalized medicine have been announced, including the recently launched precision medicine initiative in the US, driven by rapid advances in genomic technologies and with the promise of cheaper and better healthcare. Significant challenges remain, however, in the management and analysis of genetic information and their integration with patient data.

15 Feb 2015

Immune system exploits flu virus' dependence on host's machinery

Viruses are masters of outsourcing, entrusting their fundamental function - reproduction - to the host cells they infect. But it turns out this highly economical approach also creates vulnerability.

13 Feb 2015

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

In May 2015 Atlanta will host Biotechnology and the Ethical Imagination: A Global Summit (BEINGS), an international summit drawing together the world's thought leaders on the highly debated issues of cellular biotechnology.

13 Feb 2015

New study indicates that malaria-causing parasite is unlikely to cross from animals to humans

In recent years, public health experts have increasingly explored the idea of eliminating the most dangerous malaria-causing parasite. But they have questioned whether getting rid of this species, called Plasmodium falciparum, would allow other species of the parasite to simply jump into the gap and start infecting humans with malaria.

13 Feb 2015

Groundbreaking research aims to provide more effective treatment for women with cervical cancer

UNIVERSITY of Huddersfield researcher Dr Tsitsi Chituku is taking part in a project that seeks to learn more about the genetic factors that make some women more susceptible to cervical cancer. It was a recent visit to Africa, to carry out a health screening project involving hundreds of women, which helped to shape the emphasis of her research.

12 Feb 2015

RAB3GAP complex plays important role in autophagy

Neurodegenerative disorders such as Alzheimer's disease are typically characterized by protein deposits in the brain. These are comprised of defective, insoluble proteins which no longer fulfill their function and which cells are unable to break down. The work group headed by Professor Christian Behl of the Institute of Pathobiochemistry of the University Medical Center of Johannes Gutenberg University Mainz has determined the RAB3GAP complex as a novel factor that influences the efficient degradation of proteins.

12 Feb 2015

Researchers identify molecular pathways associated with distinct subsets of SSc patients

For years, doctors have been baffled about why some patients with systemic sclerosis (SSc) respond to therapy while others do not.

12 Feb 2015

Parents' lifestyles rather than their genes responsible for childhood obesity, shows study

Parents' lifestyles, rather than their genes, are primarily responsible for their children being overweight according to research by the Centre for Economic Performance, based at the London School of Economics and Political Science (LSE).

12 Feb 2015

UH professor wins Friedrich Wilhelm Bessel Research Award

University of Houston developmental psychology professor Arturo Hernandez is among this year's recipients of the Friedrich Wilhelm Bessel Research Award. The award honors his work in mapping how the brain processes language. This research has implication on how language - including a second language - is taught and learned.

12 Feb 2015

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Researchers at Oregon State University have discovered that antibiotics have an impact on the microorganisms that live in an animal's gut that's more broad and complex than previously known.

11 Feb 2015

Single genomic change can make beneficial bacteria into pathogenic bacteria

We, as most animals, host many different beneficial bacteria. Being beneficial to the host often pays off for the bacteria, as success of the host determines the survival and spread of the microbe. But if bacteria grow too much they may become deadly.

11 Feb 2015

UNC researchers create new research tool to help crack the histone code

University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants.

11 Feb 2015

TUSM researchers awarded $7.4 million to study brain impairment in patients infected with HIV

Researchers at Temple University School of Medicine have been awarded a $7.4 million, five-year grant from the National Institute on Drug Abuse to determine how cocaine and HIV-1 interact to cause brain impairment in patients infected with the human immunodeficiency virus.

11 Feb 2015

Experimental Ebola virus medication shows promise in monkeys

An experimental medication that targets a protein in Ebola virus called VP24 protected 75% of a group of monkeys that were studied from Ebola virus infection, according to new research conducted by the U.S. Army, in collaboration with Sarepta Therapeutics, Inc.

10 Feb 2015

Psychedelic drug prevents allergic asthma in mouse model

Research led by Charles Nichols, PhD, Associate Professor of Pharmacology and Experimental Therapeutics at the LSU Health New Orleans School of Medicine, has found that a psychedelic drug, (R)-DOI, prevents the development of allergic asthma in a mouse model.

10 Feb 2015

New research provides hope for treating stroke using HUCBCs

Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert their therapeutic effects has not been clear. Now, a research team from the University of South Florida using animal models of stroke has found that the HUCBCs are most beneficial in preventing neuron loss when the Akt signaling pathway is activated by secretions from the HUCBCs and that Akt activation subsequently impacts a specific gene involved in reducing inflammation.

10 Feb 2015

Genes News and Research

Researchers discover molecular 'switch' that controls replication, transcription of mitochondria DNA

Researchers develop novel strategy in fight against cancer

Scientists find seven new genes that can cause X-linked intellectual disability

Researcher uses Gene Rank technique to capture, describe gene connectivity

A*STAR's GIS scientists develop new system that can predict treatment targets for cancer

Immune system exploits flu virus' dependence on host's machinery

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

New study indicates that malaria-causing parasite is unlikely to cross from animals to humans

Groundbreaking research aims to provide more effective treatment for women with cervical cancer

RAB3GAP complex plays important role in autophagy

Researchers identify molecular pathways associated with distinct subsets of SSc patients

Parents' lifestyles rather than their genes responsible for childhood obesity, shows study

UH professor wins Friedrich Wilhelm Bessel Research Award

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Single genomic change can make beneficial bacteria into pathogenic bacteria

UNC researchers create new research tool to help crack the histone code

TUSM researchers awarded $7.4 million to study brain impairment in patients infected with HIV

Experimental Ebola virus medication shows promise in monkeys

Psychedelic drug prevents allergic asthma in mouse model

New research provides hope for treating stroke using HUCBCs

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