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Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

New mathematical model can calculate the risk of resistance evolution for drug pairs

Bacteria have dangerously evolved to thwart many of the medicines that were designed to kill them. As a result, a growing antibiotic resistance crisis is responsible for more than 700,000 deaths each year, emerging as one of the world's most pressing health issues.

19 Jan 2022

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

A new study discusses the targeted discovery of NTD-reactive antibodies from an individual who had recovered from SARS-CoV-2 infection.

19 Jan 2022

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

19 Jan 2022

New topical cream could help prevent frostbite injuries

Skiers, hikers, soldiers and others exposed to extreme cold temperatures can experience frostbite - a painful injury that occurs when ice crystals form in the skin. Many extremely cold areas are also remote, and delays in frostbite treatment can result in severe wounds, scarring and even limb amputation

19 Jan 2022

'Retinal age gap' can be an independent predictor of increased mortality risk

The difference between the biological age of the retina, the light sensitive layers of nerve tissue at the back of the eye, and a person's real (chronological) age, is linked to their risk of death, finds research published online in the British Journal of Ophthalmology.

19 Jan 2022

Scientists reveal toxic astrocyte changes in ALS

Scientists at the Francis Crick Institute have revealed harmful changes in supporting cells, called astrocytes, in Amyotrophic Lateral Sclerosis (ALS) in two publications in Brain and Genome Research.

19 Jan 2022

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

In a new study, researchers used bioinformatics tools to explore the biological characteristics of SARS-CoV-2-infected myocardium.

19 Jan 2022

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Independent drug action, not synergy nor additivity, accounted for the clinical efficacy of nearly all examined combination therapies involving immune checkpoint inhibitors in clinical trials, according to results from a retrospective analysis.

19 Jan 2022

Study explores COVID-19 diagnosis and outcomes in HIV patients

In a new study, researchers determined the effect of the human immunodeficiency virus (HIV) on coronavirus disease 2019 (COVID-19) diagnosis and disease outcomes and compared to those without HIV.

19 Jan 2022

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Researchers have discovered a new way to induce immunity against the RBD.

19 Jan 2022

Impact of atrial fibrillation in COVID-19 vaccine-induced pericarditis patients

In a new study, a team of researchers described the case of a healthy 49-year old male patient with new-onset atrial fibrillation after receiving the second dose of the COVID-19 mRNA-1273 (Moderna) vaccine.

19 Jan 2022

Impact of COVID-19 on male and female reproductive health

A new review article investigated the relation between SARS-CoV-2 infection and reproductive health.

19 Jan 2022

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

A recent review discusses the engineering versatility of polymeric nanoparticles - making a good therapeutic alternative against coronavirus diseases.

19 Jan 2022

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

New therapies for autoimmune rheumatic diseases (AIRDs) that are designed to better regulate lipid (fat) metabolism, could significantly reduce the harmful side-effects caused by conventional treatments, finds a new large-scale review led by UCL researchers.

19 Jan 2022

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

A combination of anti-cancer antibodies produced a powerfully synergistic response in two hard-to-treat pediatric cancers, according to a new study, in mice, led by researchers at the Stanford University School of Medicine.

19 Jan 2022

New method reverses insecticide resistance using CRISPR/Cas9 technology

Insecticides play a central role in efforts to counter global impacts of mosquito-spread malaria and other diseases, which cause an estimated 750,000 deaths each year. These insect-specific chemicals, which cost more than $100 million to develop and bring to market, also are critical to controlling insect-driven damage on crops that poses a challenge to food security.

18 Jan 2022

Cell News and Research

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

New mathematical model can calculate the risk of resistance evolution for drug pairs

Novel antibody that targets the N-terminal domain of SARS-CoV-2 identified

Yale research sheds light on the lifespan and myriad functions of messenger RNAs

New topical cream could help prevent frostbite injuries

'Retinal age gap' can be an independent predictor of increased mortality risk

Scientists reveal toxic astrocyte changes in ALS

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Study explores COVID-19 diagnosis and outcomes in HIV patients

Study reports of receptor-binding domain multimer capable of enhancing the immune response against SARS-CoV-2

Impact of atrial fibrillation in COVID-19 vaccine-induced pericarditis patients

Impact of COVID-19 on male and female reproductive health

The latest advancements in polymer-based nanotechnology approaches used to fight against SARS-CoV-2

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

Antibody combination produces a synergistic response in difficult-to-treat pediatric cancers

New method reverses insecticide resistance using CRISPR/Cas9 technology

Scientists assess ACE2 binding and antigenicity of Mu (B.1.621) and A.2.5 spikes

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

Contagious cancers can jump between marine clam species, study shows

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