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SLU researcher discovers new information about how antibiotics stop staph infections

In research published in Proceedings of the National Academy of Sciences, assistant professor of biochemistry and molecular biology at Saint Louis University Mee-Ngan F. Yap, Ph.D., discovered new information about how antibiotics like azithromycin stop staph infections, and why staph sometimes becomes resistant to drugs.

23 Jan 2015

First Major Analysis Of Human Protein Atlas Is Published In Science

A research article published today in Science presents the first major analysis based on the Human Protein Atlas, including a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.

23 Jan 2015

Study uses 'systems genetics' approach to identify potential target for epilepsy

A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research.

23 Jan 2015

International study identifies genetic factors that influence the size of brain structures

An international study, which included researchers from NUI Galway, has identified significant genetic factors that influence the size of structures within the brain. It is hoped these new insights may help scientists better understand disorders such as schizophrenia, Alzheimer's disease and epilepsy.

23 Jan 2015

New Baylor research explores novel non-invasive technology for pediatric eye exams

Picture a toddler getting his first eye exam. He's seated in a strange room, with strange instruments and strange bright lights. He can't sit still or open his eyes long enough for that diagnostic poof of air - especially if he has trouble seeing anyway, as children with achromatopsia do.

23 Jan 2015

PKC enzymes categorized as cancer promoters are actually tumor suppressors

Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes' activities.

23 Jan 2015

New study links inflammatory bowel diseases to increase in diversity of viruses

Inflammatory bowel diseases are associated with a decrease in the diversity of bacteria in the gut, but a new study led by researchers at Washington University School of Medicine in St. Louis has linked the same illnesses to an increase in the diversity of viruses.

23 Jan 2015

UAB Research Probes Molecular Basis Of Rare Genetic Disorder

An international group co-led by University of Alabama at Birmingham researcher Mary MacDougall, Ph.D., has unraveled the molecular basis for the rare, inherited genetic disorder, Singleton-Merten Syndrome (SMS). Individuals with SMS develop extreme, life-threatening calcification of the aorta and heart valves, early-onset periodontitis and root resorption of the teeth, decreases in bone density, and loss of bone tissue at the tips of fingers and toes.

23 Jan 2015

Researchers find CREB-activated genes in long-term memory-trained worms

A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging.

23 Jan 2015

Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

Inflammation has long been studied in Alzheimer's, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease.

23 Jan 2015

Study identifies gene that may become resistant to current testicular cancer treatments

A major research study has uncovered several new genetic mutations that could drive testicular cancer - and also identified a gene which may contribute to tumours becoming resistant to current treatments.

22 Jan 2015

Researchers reveal role of epigenetic factors in malignant skin cancer

Melanoma, the most aggressive of all skin cancer strains, is often fatal for patients due to the pronounced formation of metastases. Until now, a melanoma's rampant growth was mainly attributed to genetic causes, such as mutations in certain genes. However, researchers from the University of Zurich now reveal that so-called epigenetic factors play a role in the formation of metastases in malignant skin cancer. This opens up new possibilities for future cancer treatments.

22 Jan 2015

Cornell scientists develop new computational method to identify functional human genome

Striving to unravel and comprehend DNA's biological significance, Cornell University scientists have created a new computational method that can identify positions in the human genome that play a role in the proper functioning of cells, according to a report published Jan. 19 in the journal Nature Genetics.

22 Jan 2015

ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

In the largest collaborative study of the brain to date, researchers from the Keck School of Medicine of the University of Southern California led a global consortium of 190 institutions to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer's disease, autism and other neurological conditions.

22 Jan 2015

Two new drug compounds appear to be effective in treating endometriosis

Two new drug compounds - one of which has already proven useful in a mouse model of multiple sclerosis - appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine.

22 Jan 2015

Genes that increase longevity may not increase healthy lifespan

A study of long-lived mutant C. elegans by scientists at the University of Massachusetts Medical School shows that the genetically altered worms spend a greater portion of their life in a frail state and exhibit less activity as they age then typical nematodes.

22 Jan 2015

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Researchers reveal key factor in understanding elevated cancer risk linked to gene therapy

National Institutes of Health researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy. They conducted research on mice with a rare disease similar to one in humans, hoping their findings may eventually help improve gene therapy for humans. Researchers at the National Human Genome Research Institute, part of NIH, published their research in the Jan. 20, 2015, online issue of the Journal of Clinical Investigation.

21 Jan 2015

Researchers identify ten new antibodies that can possibly prevent cancer tumours

Out of a library with billions of artificial antibodies, researchers have identified ten that can possibly prevent cancer tumours from growing.

20 Jan 2015

Research opens door to potential new cancer biomarkers

A new analysis opens the door to discovery of thousands of potential new cancer biomarkers.

20 Jan 2015

Genes News and Research

SLU researcher discovers new information about how antibiotics stop staph infections

First Major Analysis Of Human Protein Atlas Is Published In Science

Study uses 'systems genetics' approach to identify potential target for epilepsy

International study identifies genetic factors that influence the size of brain structures

New Baylor research explores novel non-invasive technology for pediatric eye exams

PKC enzymes categorized as cancer promoters are actually tumor suppressors

New study links inflammatory bowel diseases to increase in diversity of viruses

UAB Research Probes Molecular Basis Of Rare Genetic Disorder

Researchers find CREB-activated genes in long-term memory-trained worms

Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

Study identifies gene that may become resistant to current testicular cancer treatments

Researchers reveal role of epigenetic factors in malignant skin cancer

Cornell scientists develop new computational method to identify functional human genome

ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

Two new drug compounds appear to be effective in treating endometriosis

Genes that increase longevity may not increase healthy lifespan

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Researchers reveal key factor in understanding elevated cancer risk linked to gene therapy

Researchers identify ten new antibodies that can possibly prevent cancer tumours

Research opens door to potential new cancer biomarkers

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