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SUMO1 gene implicated in cleft lip and palate defects

Researchers supported by the National Institutes of Health report in the current issue of the journal Science that a much-studied gene called SUMO1, when under expressed, can cause cleft lip and palate, one of the world's most common birth defects.

21 Sep 2006

Insulin receptor stops progression of Alzheimer's disease

Stimulation of a receptor in the brain that controls insulin responses has been shown to halt or diminish the neurodegeneration of Alzheimer's disease, providing evidence that the disease can be treated in its early stages, according to a study by researchers at Rhode Island Hospital and Brown Medical School.

21 Sep 2006

Nitric oxide helps pregnant women with hypertension

Nitric oxide (NO) is best known as an air pollutant produced by vehicle emissions and power plants but for pregnant women it is a crucial compound required to avoid hypertension and pre-eclampsia.

21 Sep 2006

Leptin could combat type 2 diabetes

University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more Americans pack on extra pounds.

21 Sep 2006

Study reveals white blood cells can both hurt and help transplanted kidneys

In an example of biological irony, the same white blood cell chemistry known to damage kidneys used for transplants may also help prevent such damage, according to a federally funded study in genetically engineered mice at Johns Hopkins.

21 Sep 2006

Carbon monoxide shown to reverse symptoms of pulmonary hypertension

In a medical case of Jekyll and Hyde, carbon monoxide - the highly toxic gas emitted from auto exhausts and faulty heating systems - has proven effective in treating the symptoms of pulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death.

20 Sep 2006

Researchers discover clues to the cause of T-cell acute lymphoblastic leukemia

Researchers' discovery of clues to the cause of T-cell acute lymphoblastic leukemia (T-ALL) - a form of pediatric cancer that has a very poor prognosis - could lead to the development of new targeted therapies for this extremely difficult disease.

20 Sep 2006

Earlier detection and treatment of kidney cancer not decreasing mortality

The number of cases of kidney cancer has been rising over the last two decades, and new research from the University of Michigan Comprehensive Cancer Center shows that this increase is driven largely by the detection of small, presumably curable, kidney masses.

19 Sep 2006

Latest studies reveal more risks with Vioxx

Two major studies by experts in the U.S. and Australia have provided new evidence of the cardiovascular and kidney risks attached to both COX-2 inhibitors and NSAID painkillers.

18 Sep 2006

Restricting air travel could slow down the spread of bird flu pandemic

According to researchers, a noticeable drop in the number of people travelling by air following the September 11 attacks, had an effect on the start and spread of the 2001-2002 U.S. flu season.

13 Sep 2006

Green tea slows down plaque formation in Huntington's disease

Green tea can apparently inhibit the formation of the lethal protein aggregates that are a characteristic feature of Huntington's disease (HD).

13 Sep 2006

MRI tracks survival of pancreatic islets after transplantation

Magnetic resonance imaging (MRI) with an approved contrast agent may provide a practical way of monitoring the survival of transplanted pancreatic islets.

12 Sep 2006

Study compares delivery methods of schizophrenia medicines

More than half of schizophrenia patients don't take their medication as directed and a new study will determine whether biweekly physician visits and injectable drugs can change that.

12 Sep 2006

MIT device to detect and prevent epileptic seizures

Epilepsy affects about 50 million people worldwide, and while anticonvulsant medications can reduce the frequency of seizures, the drugs are ineffective for as many as one in three patients.

12 Sep 2006

Seniors who feel their 'mind is going' could very well be right

Older people who complain their "mind is going" may in fact actually be losing a part of their brain along with their memory.

12 Sep 2006

Older adults who complain their "mind is going" may be losing a part of their brain along with their memory

The study, which looked at 120 people over the age of 60, found people who complained of significant memory problems but still had normal performance on memory tests had reduced gray matter density in their brains even though they weren't diagnosed with Alzheimer's disease or mild cognitive impairment (MCI).

12 Sep 2006

Long hours cause of medical errors among residents

More than 80% of first-year medical residents work more hours than allowed by national accreditation rules, according to two studies published on Wednesday in the Journal of the American Medical Association, the Washington Post reports (Washington Post, 9/6).

6 Sep 2006

New research could help women facing high risk of stillbirth

The risk of stillbirth is particularly high for women with Type 1 or Type 2 diabetes who suffer four times as many stillbirths as non-diabetic women.

5 Sep 2006

Bipolar disorder costs twice as much in lost productivity as major depressive disorder

Bipolar disorder costs twice as much in lost productivity as major depressive disorder, a study funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) has found. Each U.S. worker with bipolar disorder averaged 65.5 lost workdays in a year, compared to 27.2 for major depression.

4 Sep 2006