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HLI gains access to PGDx's cancer genomics solutions to expand cancer genome analysis

Personal Genome Diagnostics, Inc., a provider of advanced cancer genome analysis and testing services, and Human Longevity, Inc., the human health information technology and health care company, today announced that HLI will have access to PGDx's cancer genomics solutions to expand its analysis of cancer genomes, including CancerSelect, PlasmaSelect, CancerXome, METDetect and CancerComplete.

12 Jan 2015

Study finds difference between results from IHC and quantitative molecular techniques

The cause of type 1 diabetes remains unknown. Several studies using immunohistochemistry (IHC) have independently reported hyperexpression of human leukocyte antigen (HLA) class I on pancreatic islet cells in young patients with recent-onset type 1 diabetes. Investigators have therefore suggested that HLA hyperexpression may be an important first step in the development of type 1 diabetes.

12 Jan 2015

Family history could help physicians identify prostate cancer risk

A discovery by researchers at Huntsman Cancer Institute shows that looking at whether a man's uncles and great-grandparents, among other second- and third-degree relatives, had prostate cancer could be as important as looking at whether his father had prostate cancer. A more complete family history would give physicians a new tool to decide whether or not a PSA test was appropriate.

12 Jan 2015

Biogen Idec, Columbia University Medical Center form $30 million genomics research alliance

Biogen Idec and Columbia University Medical Center have formed a $30 million strategic alliance to conduct genetics discovery research on the underlying causes of disease and to identify new treatment approaches. As part of this agreement, a sequencing and analysis facility and shared postdoctoral program will be established at Columbia to support collaborative genetics studies.

11 Jan 2015

LJI researcher awarded $1.6 million grant to study factors that trigger onset of type 1 diabetes

The American Diabetes Association has awarded La Jolla Institute researcher Stephanie Stanford, Ph.D., a $1.6 million grant to investigate the genetic and environmental factors that trigger the onset of type 1 diabetes.

11 Jan 2015

New UCLA study sheds light on why some people develop PTSD

Why do some people develop post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA discovery may shed light on the answer.

11 Jan 2015

Neuroscientists move one step closer to solving how learning and memory work

Researchers at Johns Hopkins have found out how a protein crucial to learning works: by removing a biochemical "clamp" that prevents connections between nerve cells in the brain from growing stronger.

8 Jan 2015

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center, led by Chao Cheng, PhD, have identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer.

8 Jan 2015

New research sheds light on process that controls genes and determines cell fate

For a skin cell to do its job, it must turn on a completely different set of genes than a liver cell — and keep genes it doesn’t need switched off. One way of turning off large groups of genes at once is to send them to “time-out” at the edge of the nucleus, where they are kept quiet. New research from Johns Hopkins sheds light on how DNA gets sent to the nucleus’ far edge, a process critical to controlling genes and determining cell fate.

7 Jan 2015

Glaucoma Awareness Month: Mount Sinai ophthalmologists offer tips for glaucoma prevention

Glaucoma, a degenerative eye disease that causes damage to the optic nerve, is the second leading cause of blindness in the world, according to the World Health Organization. To observe Glaucoma Awareness Month, ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai and the Mount Sinai Health System are offering tips for prevention and early detection of the condition.

7 Jan 2015

Research may provide new route to prevention and treatment of diabetes

An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say.

6 Jan 2015

U-M researchers reveal key gene that may provide potential target for cancer treatment

One of the mysteries in cancer biology is how one protein, TGF-beta, can both stop cancer from forming and encourage its aggressive growth.

6 Jan 2015

Johns Hopkins scientists use genome editing technology to alter human stem cells

A powerful “genome editing” technology known as CRISPR has been used by researchers since 2012 to trim, disrupt, replace or add to sequences of an organism’s DNA.

6 Jan 2015

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment

Sirnaomics, Inc. and its affiliate Suzhou Sirnaomics Pharmaceutics, Co. Ltd., together with its partner Guangzhou Xiangxue Pharmaceutical, Co. Ltd., (SZSE: 300147), have formally submitted an Investigational New Drug (IND) Application to the China Food and Drug Administration for STP705, an anti-fibrosis RNA interference (RNAi) therapeutic for prevention and treatment of human skin hypertrophic scars.

5 Jan 2015

Healthy Nordic diet reduces expression of inflammation-associated genes in adipose tissue

A Nordic study led by the Institute of Public Health and Clinical Nutrition at the University of Eastern Finland discovered that the health-promoting Nordic diet reduces the expression of inflammation-associated genes in subcutaneous adipose tissue. In overweight persons, the expression of these genes reduced without weight loss.

5 Jan 2015

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide.

2 Jan 2015

Top cancer research and clinical developments at Dana-Farber Cancer Institute in 2014

Immunotherapy, genomic profiling, and investigating game-changing drug therapies topped the list of most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014.

1 Jan 2015

LIBD announces significant advances in identifying causes of schizophrenia, brain disorders

The Lieber Institute for Brain Development (LIBD) announces significant advances in identifying the causes of schizophrenia and related developmental brain disorders and translating these findings into new treatment strategies.

31 Dec 2014

Researchers use whole genome sequencing to track evolution of chicken flu virus

An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel avian H7N9 influenza A virus that has sickened more than 375 people since 2013. The research appears in the current online early edition of the scientific journal Proceedings of the National Academy of Sciences.

30 Dec 2014

Intriguing small molecule directs activity of key ‘clock proteins’

In research published in Nature Communications, Thomas Burris, Ph.D., chair of pharmacological and physiological science at Saint Louis University, reports intriguing findings about a small molecule that directs the activity of key "clock proteins," offering the potential to manage circadian rhythm and treat problems that are associated with its dysfunction, like sleep and anxiety disorders.

24 Dec 2014

Genes News and Research

HLI gains access to PGDx's cancer genomics solutions to expand cancer genome analysis

Study finds difference between results from IHC and quantitative molecular techniques

Family history could help physicians identify prostate cancer risk

Biogen Idec, Columbia University Medical Center form $30 million genomics research alliance

LJI researcher awarded $1.6 million grant to study factors that trigger onset of type 1 diabetes

New UCLA study sheds light on why some people develop PTSD

Neuroscientists move one step closer to solving how learning and memory work

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

New research sheds light on process that controls genes and determines cell fate

Glaucoma Awareness Month: Mount Sinai ophthalmologists offer tips for glaucoma prevention

Research may provide new route to prevention and treatment of diabetes

U-M researchers reveal key gene that may provide potential target for cancer treatment

Johns Hopkins scientists use genome editing technology to alter human stem cells

Sirnaomics submits STP705 IND Application to CFDA for skin scar treatment

Healthy Nordic diet reduces expression of inflammation-associated genes in adipose tissue

Johns Hopkins scientists create statistical model to measure proportion of cancer incidence

Top cancer research and clinical developments at Dana-Farber Cancer Institute in 2014

LIBD announces significant advances in identifying causes of schizophrenia, brain disorders

Researchers use whole genome sequencing to track evolution of chicken flu virus

Intriguing small molecule directs activity of key ‘clock proteins’

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