Genes News and Research

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Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

While people of Mexican ancestry are nearly twice as likely to develop Type 2 diabetes as people of European heritage, the majority of research in this area has focused on those of European origin.

18 Dec 2014

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Two related proteins exert a lethal double whammy effect against glioblastoma cells when activated with a small molecule, say researchers at Georgetown Lombardi Comprehensive Cancer Center.

18 Dec 2014

Study offers insights into mechanisms of bacterial resistance to antimicrobial peptides

Antimicrobial peptides are a distinctive class of potent, broad-spectrum antibiotics produced by the body's innate immune system--the first line of defense against disease-causing microbes.

18 Dec 2014

Research findings may lead to new treatment strategies for Ewing sarcoma

The genetic abnormality that drives the bone cancer Ewing sarcoma operates through two distinct processes - both activating genes that stimulate tumor growth and suppressing those that should keep cancer from developing. These findings by Massachusetts General Hospital investigators, published in the November issue of Cancer Cell, may lead to new therapies targeting these aberrant mechanisms.

18 Dec 2014

Tel Aviv University study throws spotlight on gene mutation responsible for premature ovarian failure

Premature ovarian failure, also known as primary ovarian insufficiency (POI), affects 1% of all women worldwide. In most cases, the exact cause of the condition, which is often associated with infertility, is difficult to determine.

18 Dec 2014

Scientists discover how certain gut bacteria can protect themselves, others from antibiotics

Scientists from the Institute of Food Research and the University of East Anglia have discovered how certain gut bacteria can protect themselves and others in the gut from antibiotics.

18 Dec 2014

New study identifies how SNAIL gene helps cancer cells break free from primary tumor

More than 90 percent of cancer-related deaths are caused by the spread of cancer cells from their primary tumor site to other areas of the body. A new study has identified how one important gene helps cancer cells break free from the primary tumor.

18 Dec 2014

Researchers identify 53 existing drugs that may block Ebola virus from entering human cells

Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health, and published today in the Nature Press journal Emerging Microbes and Infections.

17 Dec 2014

Researchers use novel technique to identify microlesions in brain tissue from epileptic patients

Using an innovative technique combining genetic analysis and mathematical modeling with some basic sleuthing, researchers have identified previously undescribed microlesions in brain tissue from epileptic patients. The millimeter-sized abnormalities may explain why areas of the brain that appear normal can produce severe seizures in many children and adults with epilepsy.

17 Dec 2014

Novel technique to identify biological markers in brain development

With a unique, multi-faceted approach, researchers at the Lieber Institute for Brain Development have quantified the effect of previously unidentified anomalies in genetic expression that determine how the human brain develops from its earliest stages.

17 Dec 2014

Mitochondrial DNA may predict overall risk of frailty, death

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

17 Dec 2014

New study shows that people may inherit intestinal bacteria that cause inflammatory bowel disease

A new study by an international team of researchers shows for the first time that people may inherit some of the intestinal bacteria that cause Crohn's disease and ulcerative colitis, collectively know as inflammatory bowel disease (IBD). The study, recently published in Genome Medicine, also confirmed that antibiotics could worsen the imbalance in the gut microbes.

16 Dec 2014

Joslin study could lead to improved anti-aging drugs

In a study published today by Nature, researchers at Joslin Diabetes Center used a microscopic worm (C. elegans) to identify a new path that could lead to drugs to slow aging and the chronic diseases that often accompany it--and might even lead to better cosmetics.

16 Dec 2014

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer.

16 Dec 2014

New MIT study implicates RNA-binding proteins in regulation of cancer

A new study from MIT implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated with increased proliferation.

16 Dec 2014

Leicester biologist examines zebrafish to understand pathological aggression

An international research consortium, including a biologist from Leicester, has heard that aggression in young male prisoners can be reduced by treating ADHD.

16 Dec 2014

Novel marker may help doctors choose most effective treatment for older patients with AML

A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute describes a novel marker that might help doctors choose the least toxic, most effective treatment for many older patients with acute myeloid leukemia (AML).

15 Dec 2014

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

UT Southwestern Medical Center researchers have identified a possible therapy to treat neurofibromatosis type 1 or NF1, a childhood neurological disease characterized by learning deficits and autism that is caused by inherited mutations in the gene encoding a protein called neurofibromin.

15 Dec 2014

Environmental factors influence how genetic variants affect the brain, behaviour

Both positive and negative experiences influence how genetic variants affect the brain and thereby behaviour, according to a new study. "Evidence is accumulating to show that the effects of variants of many genes that are common in the population depend on environmental factors.

14 Dec 2014

Experiments to probe bacteria virulence in low gravity of space station

The University of Colorado Boulder will fly state-of-the-art hardware on the commercial SpaceX Dragon spacecraft launching to the International Space Station Dec. 19 to support experiments designed to better understand why the virulence of some pathogens increases in the low gravity of space.

14 Dec 2014

Genes News and Research

Researchers examine why Mexican-Americans at increased risk for Type 2 diabetes

Two orphan receptor proteins exert fatal double whammy effect against glioblastoma cells

Study offers insights into mechanisms of bacterial resistance to antimicrobial peptides

Research findings may lead to new treatment strategies for Ewing sarcoma

Tel Aviv University study throws spotlight on gene mutation responsible for premature ovarian failure

Scientists discover how certain gut bacteria can protect themselves, others from antibiotics

New study identifies how SNAIL gene helps cancer cells break free from primary tumor

Researchers identify 53 existing drugs that may block Ebola virus from entering human cells

Researchers use novel technique to identify microlesions in brain tissue from epileptic patients

Novel technique to identify biological markers in brain development

Mitochondrial DNA may predict overall risk of frailty, death

New study shows that people may inherit intestinal bacteria that cause inflammatory bowel disease

Joslin study could lead to improved anti-aging drugs

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

New MIT study implicates RNA-binding proteins in regulation of cancer

Leicester biologist examines zebrafish to understand pathological aggression

Novel marker may help doctors choose most effective treatment for older patients with AML

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

Environmental factors influence how genetic variants affect the brain, behaviour

Experiments to probe bacteria virulence in low gravity of space station

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