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Experts expose fundamental role of chaos and complexity in biological information processing

The interdisciplinary approach to problems that till recently were addressed in the hermetic framework of distinct disciplines such as physics, informatics, biology or sociology constitutes today one of the most active and innovative areas of science, where fundamental issues meet problems of everyday concern.

14 Dec 2014

Researchers uncover mechanism that helps white fat cells to become browner

White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern Denmark have uncovered the mechanism by which white fat cells from humans gets reprogrammed to become browner.

14 Dec 2014

Researchers assemble first high-resolution, 3-D maps of folded genomes

In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of "genomic origami" that allows the same genome to produce different types of cells. The research appears online today in Cell.

14 Dec 2014

GSA announces recipients of 2015 Victoria Finnerty Undergraduate Travel Awards

The Genetics Society of America and the Drosophila research community are pleased to announce the recipients of the 2015 Victoria Finnerty Undergraduate Travel Awards. These awards support travel costs for undergraduates engaged in research to attend the Annual Drosophila Research Conference sponsored by GSA.

14 Dec 2014

Study sheds light on clinical and biological characteristics of male breast cancer

Results of the EORTC10085/TBCRC/BIG/NABCG International Male Breast Cancer Program conducted in both Europe and in the United States and presented at the 2014 San Antonio Breast Cancer Symposium found significant improvement in survival for men with breast cancer, but this improvement was not as good as that observed for women.

14 Dec 2014

New evidence shows how personality affects health and wellbeing

Researchers have found new evidence that explains how some aspects of our personality may affect our health and wellbeing, supporting long-observed associations between aspects of human character, physical health and longevity.

12 Dec 2014

New statistical model enables better identification of different cell types in solid tumors

A new statistical model developed by a research team at Worcester Polytechnic Institute may enable physicians to create personalized cancer treatments for patients based on the specific genetic mutations found in their tumors.

12 Dec 2014

Research finding could lead to new therapies for malignant glioma

Targeted therapies are a growing and groundbreaking field in cancer care in which drugs or other substances are designed to interfere with genes or molecules that control the growth and survival of cancer cells. Now, scientists at Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine (VIMM) have identified a novel interaction between a microRNA and a gene that could lead to new therapies for the most common and deadly form of brain tumor, malignant glioma.

12 Dec 2014

IRCM researchers uncover mechanism that regulates dopamine levels in the brain

Researchers in Montréal led by Jacques Drouin, D.Sc., uncovered a mechanism regulating dopamine levels in the brain by working on a mouse model of late onset Parkinson's disease.

12 Dec 2014

Claritas, NextCODE Health partner to bring global leadership in pediatric medicine, sequence analysis

To rapidly expand the use and power of genomic sequencing for diagnosing and treating rare diseases, Claritas Genomics and NextCODE Health today announced a strategic partnership bringing together global leadership in pediatric medicine and sequence analysis. Claritas Genomics, affiliated with Boston Children's Hospital, is a CLIA-certified clinical laboratory serving the DNA-based diagnostic testing needs of children's hospitals that admit hundreds of thousands of patients with genetic disorders every year.

11 Dec 2014

Researchers pinpoint rare gene mutations that increase risk of heart attack early in life

A team of investigators from the Broad Institute, Massachusetts General Hospital and other leading biomedical research institutions has pinpointed rare mutations in a gene called APOA5 that increase a person's risk of having a heart attack early in life. These mutations disable the APOA5 gene and also raise the levels in the blood of triglyceride-rich lipoproteins, a type of fat.

11 Dec 2014

UT Southwestern microbiologists identify key gut bacteria that promotes foodborne infections

UT Southwestern Medical Center microbiologists have identified key bacteria in the gut whose resources are hijacked to spread harmful foodborne E. coli infections and other intestinal illnesses.

11 Dec 2014

New therapeutic approach for women with estrogen-receptor-positive breast cancer

Loyola researchers and collaborators have reported promising results from a novel therapeutic approach for women with estrogen-receptor-positive breast cancer.

11 Dec 2014

New technique allows rapid, large-scale studies of gene function

Using a gene-editing system originally developed to delete specific genes, MIT researchers have now shown that they can reliably turn on any gene of their choosing in living cells.

11 Dec 2014

STSI researchers launch study to examine root cause of sudden unexpected death

Researchers at the Scripps Translational Science Institute have launched a clinical trial aimed at cracking one of the toughest mysteries in forensic science -- sudden unexplained death.

11 Dec 2014

Johns Hopkins study shows gene expression in autism brains

While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. The study, a collaborative effort between Johns Hopkins and the University of Alabama at Birmingham, included data from 72 autism and control brains.

11 Dec 2014

New study reveals how COX-2 inhibitors can increase risk of heart attack in arthritis patients

A class of drug for treating arthritis - all but shelved over fears about side effects - may be given a new lease of life, following the discovery of a possible way to identify which patients should avoid using it.

11 Dec 2014

Simple supplement could reduce heart disease in individuals born with low birth weight

A simple supplement could be a safe and cost-effective way of reducing heart disease in individuals born with a low birth weight, suggests research from the University of Cambridge. The study, carried out in rats, also raises the possibility of developing a blood test to indicate how much damage there is in the aortas of these individuals.

10 Dec 2014

Myriad Genetics highlights three new studies at SABCS 2014

Myriad Genetics, Inc. today announced results from a new study that demonstrated the ability of the myRisk Hereditary Cancer test to detect 105 percent more mutations in cancer causing genes than conventional BRCA testing alone. The Company also presented two key studies in triple negative breast cancer (TNBC) that show the myChoice HRD test accurately predicted response to platinum-based therapy in patients with early-stage TNBC and that the BRACAnalysis molecular diagnostic test significantly predicted response to platinum-based drugs in patients with metastatic TNBC.

10 Dec 2014

Study: Long-term endurance training alters epigenetic pattern in the human skeletal muscle

A new study from Karolinska Institutet in Sweden shows that long-term endurance training in a stable way alters the epigenetic pattern in the human skeletal muscle. The research team behind the study, which is being published in the journal Epigenetics, also found strong links between these altered epigenetic patterns and the activity in genes controlling improved metabolism and inflammation.

10 Dec 2014

Genes News and Research

Experts expose fundamental role of chaos and complexity in biological information processing

Researchers uncover mechanism that helps white fat cells to become browner

Researchers assemble first high-resolution, 3-D maps of folded genomes

GSA announces recipients of 2015 Victoria Finnerty Undergraduate Travel Awards

Study sheds light on clinical and biological characteristics of male breast cancer

New evidence shows how personality affects health and wellbeing

New statistical model enables better identification of different cell types in solid tumors

Research finding could lead to new therapies for malignant glioma

IRCM researchers uncover mechanism that regulates dopamine levels in the brain

Claritas, NextCODE Health partner to bring global leadership in pediatric medicine, sequence analysis

Researchers pinpoint rare gene mutations that increase risk of heart attack early in life

UT Southwestern microbiologists identify key gut bacteria that promotes foodborne infections

New therapeutic approach for women with estrogen-receptor-positive breast cancer

New technique allows rapid, large-scale studies of gene function

STSI researchers launch study to examine root cause of sudden unexpected death

Johns Hopkins study shows gene expression in autism brains

New study reveals how COX-2 inhibitors can increase risk of heart attack in arthritis patients

Simple supplement could reduce heart disease in individuals born with low birth weight

Myriad Genetics highlights three new studies at SABCS 2014

Study: Long-term endurance training alters epigenetic pattern in the human skeletal muscle

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics