Genes News and Research

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Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

Researchers from Huntsman Cancer Institute at the University of Utah discovered the unusual role of lactate in the metabolism of alveolar soft part sarcoma (ASPS), a rare, aggressive cancer that primarily affects adolescents and young adults. The study also confirmed that a fusion gene is the cancer-causing agent in this disease.

27 Nov 2014

New research brings personalized cancer vaccine approach one step closer to reality

In the near future, physicians may treat some cancer patients with personalized vaccines that spur their immune systems to attack malignant tumors. New research led by scientists at Washington University School of Medicine in St. Louis has brought the approach one step closer to reality.

27 Nov 2014

New microbial analysis has implications for protecting environment, energy recovery and human health

An international team of scientists from the Translational Genomics Research Institute and The Luxembourg Centre for Systems Biomedicine have completed a first-of-its-kind microbial analysis of a biological wastewater treatment plant that has broad implications for protecting the environment, energy recovery and human health.

27 Nov 2014

Researchers uncover easily detectable, 'pre-malignant' state in the blood

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and Harvard-affiliated hospitals have uncovered an easily detectable, "pre-malignant" state in the blood that significantly increases the likelihood that an individual will go on to develop blood cancers such as leukemia, lymphoma, or myelodysplastic syndrome.

27 Nov 2014

Biologist Marnie Halpern selected as AAAS Fellow

Biologist Marnie Halpern of Carnegie's Department of Embryology has been named a Fellow of the American Association for the Advancement of Science (AAAS) for her "fundamental contributions to developmental biology, particularly using novel genetic approaches to study patterning of the nervous system."

26 Nov 2014

Tufts University study explores relationship between transcription, expansions of DNA repeats

Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.

26 Nov 2014

Leeds researchers identify gene associated with autism symptoms

Researchers at the University of Leeds have shed light on a gene mutation linked to autistic traits. The team already knew that some people with autism were deficient in a gene called neurexin-II.

26 Nov 2014

New Sophia DDM platform offers full BRCA1/2 analysis on a single NGS run

Sophia Genetics, the European leader in Clinical Genomics and Next Generation DNA Sequencing (NGS), has today launched a major upgrade to its Data Driven Medicine Platform (Sophia DDM), offering full BRCA1/2 analysis on a single NGS (Next Generation Sequencing) run, for the first time.

26 Nov 2014

New hybrid vehicle to improve delivery of DNA vaccines is under development

Described recently in the Proceedings of the National Academy of Sciences, the technology is a biomedical advancement that could help unleash the potential of DNA vaccines, which despite two decades of research, have yet to make a significant impact in the treatment of major illnesses.

26 Nov 2014

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Genes make proteins and proteins tell your body's cells what to do: one talks to the next, which talks to the next, and to the next. Like a game of telephone, researchers call these "signaling pathways". Abnormalities in these signaling pathways can cause the growth and survival of cancer cells. Commonly, mutations or rearrangements of genes in the MAPK signaling pathway create cancer's fast growth, and alterations in the PI3K signaling pathway allow cancer cells to survive into virtual immortality.

26 Nov 2014

Decrease in prevalence of VRSA infections in southeastern Michigan

A new study finds a decrease in an emergent strain of methicillin-resistant S. aureus (MRSA) that is resistant to last line defense antibiotics. Researchers examined the prevalence of vancomycin-resistant Staphylococcus aureus (VRSA) infections in southeastern Michigan, where the majority of these infections have occurred in the U.S.

26 Nov 2014

Research sheds light on gene mutation linked to autistic traits

Researchers at the University of Leeds have shed light on a gene mutation linked to autistic traits.

25 Nov 2014

New Drexel study sheds light on the role of socioeconomic environment on diabetes risk

As the linked epidemics of obesity and diabetes continue to escalate, a staggering one in five U.S. adults is projected to have diabetes by 2050.

25 Nov 2014

Researchers discover two common genetic variants associated with memory performance

In the largest study of the genetics of memory ever undertaken, an international researcher team including scientists from Boston University School of Medicine, have discovered two common genetic variants that are believed to be associated with memory performance.

25 Nov 2014

TSRI scientists find simple method to convert human skin cells into sensory neurons

A team led by scientists from The Scripps Research Institute has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich's ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children.

25 Nov 2014

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Columbia University Medical Center has presented Andrew Hattersley, DM, and Mark McCarthy, MD, with the 16th Naomi Berrie Award for Outstanding Research in Diabetes, for their work on the genetics of the disease. Their research has contributed to the discovery of new forms of the disease, improvements in diagnostic methodology, and the development of more effective treatments.

25 Nov 2014

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research.

24 Nov 2014

NOS1AP gene may help explain biological process of schizophrenia

A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new Rutgers research.

24 Nov 2014

Study identifies H3.3 protein as key regulator in cellular senescence

Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published online this month in the journal Nature Communications.

23 Nov 2014

Researchers examine genomic landscapes of humans and mice

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

23 Nov 2014

Genes News and Research

Researchers find unusual role of lactate in metabolism of alveolar soft part sarcoma

New research brings personalized cancer vaccine approach one step closer to reality

New microbial analysis has implications for protecting environment, energy recovery and human health

Researchers uncover easily detectable, 'pre-malignant' state in the blood

Biologist Marnie Halpern selected as AAAS Fellow

Tufts University study explores relationship between transcription, expansions of DNA repeats

Leeds researchers identify gene associated with autism symptoms

New Sophia DDM platform offers full BRCA1/2 analysis on a single NGS run

New hybrid vehicle to improve delivery of DNA vaccines is under development

Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel against colorectal cancer models

Decrease in prevalence of VRSA infections in southeastern Michigan

Research sheds light on gene mutation linked to autistic traits

New Drexel study sheds light on the role of socioeconomic environment on diabetes risk

Researchers discover two common genetic variants associated with memory performance

TSRI scientists find simple method to convert human skin cells into sensory neurons

Two researchers receive Naomi Berrie Award for Outstanding Research in Diabetes

Authors review current progress in developing transgenic pig models for human diseases

NOS1AP gene may help explain biological process of schizophrenia

Study identifies H3.3 protein as key regulator in cellular senescence

Researchers examine genomic landscapes of humans and mice

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