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Expert highlights the progress and challenges in developing blood tests for Alzheimer's disease

Given the progress in therapeutics for Alzheimer's disease (AD), including the recent approval of aducanumab – the first anti-amyloid immunotherapy approved by the FDA for the disease – there is a need for simple blood tests that could be used to ensure accurate diagnosis and assess therapeutic progress.

6 Aug 2021

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

Collaborative international clinical trials testing full dose anticoagulation with heparin (a blood thinner) in both moderately ill and critically ill patients has found the treatment improves outcomes and reduces the need for vital organ support such as mechanical ventilation in moderately ill patients.

6 Aug 2021

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Immunohistochemistry staining showing PD1 expression on tumor cells in a skin biopsy from a cutaneous T-cell lymphoma patient.

5 Aug 2021

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Shuo Ma, MD, '00 PhD, associate professor of Medicine in the Division of Hematology and Oncology, was co-first author of the clinical trial published in Blood.

5 Aug 2021

COVID vaccines generate antibodies in saliva

Researchers in the United States and Canada have conducted a study showing that the vaccines developed by Pfizer-BioNTech and Moderna to protect against coronavirus disease 2019 (COVID-19) generate local antibody responses in the salivary gland that are independent of the systemic immune response.

5 Aug 2021

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Researchers remain perplexed as to why some patients infected with SARS-CoV-2, the virus responsible for COVID-19, remain asymptomatic while other patients develop severe disease symptoms.

5 Aug 2021

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Stroke patients were almost twice as likely to be functionally independent - mobile and able to perform daily tasks - at 90 days post-stroke if they were treated by a specialized mobile stroke team that traveled to them to perform mechanical clot removal, compared to those who were transferred to a thrombectomy stroke center, according to research conducted within the Mount Sinai Health System and published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

5 Aug 2021

Postpartum sleep deprivation associated with accelerated biological aging

When new mothers complain that all those sleepless nights caring for their newborns are taking years off their life, they just might be right, UCLA research published this summer in the journal Sleep Health suggests.

5 Aug 2021

Low glycemic diet results in important improvements for people with diabetes

For people with diabetes, sticking to a low glycemic diet results in small but important improvements in blood sugar levels, cholesterol, weight and other risk factors, finds a study published by The BMJ today.

5 Aug 2021

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

The use of e-cigarettes (vaping) during pregnancy poses a significant health risk for the offspring, impairing blood vessel function even into adulthood, according to a new study by researchers at West Virginia University's School of Medicine.

5 Aug 2021

Invasive 'famine weed' could escalate the spread of malaria

An invasive weed could escalate the spread of malaria in East Africa after scientists found new evidence that it creates a favourable breeding ground for female mosquitoes, which transmit malaria.

5 Aug 2021

Vitamin D supplementation could reduce opioid doses in palliative cancer treatment

Patients with vitamin D deficiency who received vitamin D supplements had a reduced need for pain relief and lower levels of fatigue in palliative cancer treatment, a randomized and placebo-controlled study by researchers at Karolinska Institutet in Sweden shows.

5 Aug 2021

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

In a recent study from University of Gothenburg, it has been shown that all participants achieve normalization of CNS injury biomarkers, regardless of previous disease severity or persistent neurological symptoms. Indicating that post-COVID-19 neurological sequalae are not due to active brain injury.

5 Aug 2021

The role of natural killer cells in the fight against coronavirus infection

This study proposes a mathematical framework to analyze the effect of the viruses on type I interferon (IFN-I) signaling, which is part of the innate immune response. IFN-I brings about natural killer cell activation, which in turn causes the activation of macrophages.

4 Aug 2021

Women voice frustration over antibiotic use and limited treatment options for UTIs

Women with frequent urinary tract infections say they're unhappy with what they perceive as their doctors' overuse of antibiotics and with the limited treatment options available to them, according to a study led by researchers from UCLA and Cedars-Sinai.

4 Aug 2021

Initiating therapeutic anticoagulation benefits moderately ill COVID-19 patients, but not critically ill patients

A large clinical trial conducted worldwide shows that treating moderately ill hospitalized COVID-19 patients with a full-dose blood thinner reduced their need for organ support, such as mechanical ventilation, and improved their chances of leaving the hospital.

4 Aug 2021

Artificial pancreas may soon help patients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of Bern, Switzerland, show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.

4 Aug 2021

Reducing antibiotic prescribing in primary care alone may not stop drug-resistant E. coli infections

Strategies to reduce antibiotic prescribing in primary care are insufficient alone to halt the rise in drug resistant E. coli infections in England, a new report concludes.

4 Aug 2021

Large catheters, small veins raise thrombosis risk for cancer patients

A world-first study led by the University of South Australia has found that cancer patients receiving chemotherapy intravenously have more than double the risk of developing a blood clot or thrombosis if the vein is too small and the catheter occupies more than 45 per cent of the vein.

4 Aug 2021

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Researchers at UT Southwestern announced successful results of a clinical trial for a commonly prescribed weight-loss drug called liraglutide.

4 Aug 2021

Blood News and Research

Expert highlights the progress and challenges in developing blood tests for Alzheimer's disease

Full dose anticoagulation with heparin improves outcomes for moderately ill COVID-19 patients

PD1 gene deletions associated with worse prognoses of cutaneous T-cell lymphomas

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

COVID vaccines generate antibodies in saliva

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Mobile interventional stroke team travels to patients for providing faster access to surgical treatment

Postpartum sleep deprivation associated with accelerated biological aging

Low glycemic diet results in important improvements for people with diabetes

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

Invasive 'famine weed' could escalate the spread of malaria

Vitamin D supplementation could reduce opioid doses in palliative cancer treatment

Post-COVID-19 neurological sequalae are not due to brain injury, study shows

The role of natural killer cells in the fight against coronavirus infection

Women voice frustration over antibiotic use and limited treatment options for UTIs

Initiating therapeutic anticoagulation benefits moderately ill COVID-19 patients, but not critically ill patients

Artificial pancreas may soon help patients with type 2 diabetes

Reducing antibiotic prescribing in primary care alone may not stop drug-resistant E. coli infections

Large catheters, small veins raise thrombosis risk for cancer patients

Common weight-loss drug successfully targets fat in adults with obesity at high cardiovascular risk

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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