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A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

A new study evaluates a commercially available IFN‐γ release assay (IGRA) to determine T-cell responses targeted against SARS-CoV-2.

26 Jul 2021

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Frontotemporal dementias are a group of fatal and debilitating brain disorders for which there are no cures.

26 Jul 2021

Air quality improvement linked with reduced risk of dementia

Improving air quality may improve cognitive function and reduce dementia risk, according to several studies reported today at the Alzheimer's Association International Conference 2021 in Denver and virtually.

26 Jul 2021

More popular type of antihypertensive drugs causes slightly more side effects

Two types of drugs that are recommended as a first treatment for patients with high blood pressure were found equally effective in improving cardiovascular outcomes, but the more popular type causes slightly more side effects, finds a multinational observational study led by researchers at Columbia University Vagelos College of Physicians and Surgeons.

26 Jul 2021

Two types of blood pressure drugs provide equal benefits, but side effects differ

People who are just beginning treatment for high blood pressure can benefit equally from two different classes of medicine - angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) - yet ARBs may be less likely to cause medication side effects, according to an analysis of real-world data published today in Hypertension, an American Heart Association journal.

26 Jul 2021

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

St. Jude Children's Research Hospital investigators have demonstrated that comprehensive genomic sequencing of all pediatric cancer patients is feasible and essential to capitalize on the lifesaving potential of precision medicine.

26 Jul 2021

New biomarkers in the eyes could unlock the key to management of diabetic retinopathy

New biomarkers found in the eyes could unlock the key to helping manage diabetic retinopathy, and perhaps even diabetes, according to new research conducted at the Indiana University School of Optometry.

26 Jul 2021

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

A recent study conducted as a part of the Real-Time Assessment of Community Transmission-2 (REACT-2) program has estimated the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among adult populations in England.

25 Jul 2021

Researchers develop ovarian tumor microenvironment-chip to test novel ways to treat the disease

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body.

23 Jul 2021

Proportion of incorrectly established paternities has decreased over time, study finds

Determining who is the biological father of a child is a sensitive subject, but the answer can be crucial in important issues.

23 Jul 2021

MUSC Hollings Cancer Center part of promising phase 2 lymphoma clinical trial

MUSC Hollings Cancer Center was one of 28 clinical sites around the world that participated in the LOTIS-2 trial to test the efficacy of Loncastuximab tesirine, a promising new treatment for aggressive B-cell lymphoma.

23 Jul 2021

Research uncovers an unexpected role for immune T cells in protection against malaria

Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.

23 Jul 2021

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

The body's first encounter with SARS-CoV-2, the virus behind COVID-19, happens in the nose and throat, or nasopharynx. A new study in the journal Cell suggests that the first responses in this battleground help determine who will develop severe disease and who will get through with mild or no illness.

23 Jul 2021

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

A new study has been published on the bioRxiv* preprint server, which has used MS to identify T cell epitopes of SARS-CoV-2 conserved protein, i.e., the membrane glycol protein (MGP) and the non-structure protein-13 (NSP13).

23 Jul 2021

Clinical trials during a pandemic – lessons from COVID-19

In this interview, Dr. Benedicte Roquebert, Dr. Stephanie Haim-Boukobza and Dr. Souad Mehlal discuss how COVID-19 has resulted in new ways to think about clinical trials during a pandemic.

From Cerba Research 23 Jul 2021

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Hematopoietic cell transplantation (HCT) is a recognized treatment option for certain blood and bone marrow cancers as well as some autoimmune and hereditary disorders.

23 Jul 2021

Freiburg surgeons develop new treatment method to improve survival after cardiac arrest

Around 50,000 people suffer sudden cardiac arrest in Germany every year. When occurring outside a hospital, the chances of survival are only ten percent. Survivors often suffer from severe permanent neurological damage.

23 Jul 2021

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

Iain Chapple, University of Birmingham, England, presented the oral session "Longitudinal Serological and Vaccination Responses to SARS-COV-2 in Dental Professionals" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

23 Jul 2021

UMD awarded grant to develop an integrated hypertension management program for older adults

To address the significant health burden of hypertension (characterized by consistently high blood pressure), the University of Maryland (UMD) was recently awarded a grant from the United States Department of Agriculture National Institute of Food and Agriculture (USDA-NIFA) to develop, test, and deliver an integrated hypertension management program for older adults.

22 Jul 2021

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

A new study characterizes the functional humoral immunity post-COVID-19 mRNA-based vaccination.

22 Jul 2021

Blood News and Research

A novel interferon-γ release assay for detection of SARS-CoV-2 specific T-cell response

Mount Sinai researchers use cerebral organoids to study frontotemporal dementia

Air quality improvement linked with reduced risk of dementia

More popular type of antihypertensive drugs causes slightly more side effects

Two types of blood pressure drugs provide equal benefits, but side effects differ

Comprehensive genomic sequencing essential to capitalize precision medicine for pediatric cancer care

New biomarkers in the eyes could unlock the key to management of diabetic retinopathy

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

Researchers develop ovarian tumor microenvironment-chip to test novel ways to treat the disease

Proportion of incorrectly established paternities has decreased over time, study finds

MUSC Hollings Cancer Center part of promising phase 2 lymphoma clinical trial

Research uncovers an unexpected role for immune T cells in protection against malaria

Blunted antiviral responses in the nasopharynx may underlie severe COVID-19

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

Clinical trials during a pandemic – lessons from COVID-19

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Freiburg surgeons develop new treatment method to improve survival after cardiac arrest

SARS-COV-2 infection leads to neutralizing and protective serological responses in over 70% of DPs

UMD awarded grant to develop an integrated hypertension management program for older adults

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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