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INTEGRA offers answers to your cell culture throughput needs

With INTEGRA electronic pipettes, you can program and store pipetting protocols and mixing routines for use across various workflows.

From INTEGRA Biosciences 14 Dec 2021

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Results of a new study show that the induction of anti-SARSCoV-2 spike saliva SIgA antibodies after vaccination is independent of the gender or type of vaccine received.

14 Dec 2021

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

An interesting new paper presents a new assay for B and T lymphocytes in individuals infected with SARS-CoV-2.

14 Dec 2021

Risk of SARS-CoV-2 reinfection in children compared to adults

The current study aimed to explore the rate and risk of SARS-CoV-2 reinfections in children.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Omicron variant may strike double vaccinated

Largely, scientists are skeptical that the Omicron variant can infect vaccinated individuals. However, a new study published on the medRxiv* preprint server has conducted neutralization assays using an Omicron isolate obtained from patients residing in the United Kingdom.

13 Dec 2021

Lymphoma patients can benefit from early CAR T treatment, study shows

Chimeric antigen receptor T-cell therapy or CAR T is a breakthrough treatment for patients with certain types of blood cancers.

13 Dec 2021

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

A new study published on the bioRxiv preprint server has hypothesized that T cell receptors (TCR) repertoire can measure the response to vaccines, as it would identify the TCR of clones that respond to the vaccination.

13 Dec 2021

Novel breathalyzer relies on viral RNA detection to diagnose SARS-CoV-2

In a new study in The Journal of Molecular Diagnostics, published by Elsevier, investigators report on the design and testing of a breathalyzer, known as the Bubbler, that relies on viral RNA detection to diagnose SARS-CoV-2.

13 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

$Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma$

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

The final results from a national phase 2 study including researchers from Yale Cancer Center show the drug tipifarnib increased survival rates for patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

13 Dec 2021

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Clinician scientists and scientists from the National Cancer Centre Singapore and A*STAR's Genome Institute of Singapore, in collaboration with Singapore General Hospital, the National University Health System, Duke-NUS Medical School, Nanyang Technological University, and collaborators from China, Malaysia, Thailand and the Philippines, have described a dynamic genomic landscape of tumour heterogeneity in hepatocellular carcinoma (HCC).

13 Dec 2021

Study offers new hope for large B-cell lymphoma patients

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, higher-intensity chemotherapy, followed by a stem cell transplant.

13 Dec 2021

Drug combination without chemotherapy can be effective in treating older patients with Ph+ ALL

The combination of dasatinib, blinatumomab, and prednisone can be effective in treating older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who are not good candidates for intensive chemotherapy treatment.

13 Dec 2021

Protein can protect the heart from damage following cancer treatment

Cancer treatment can be tough on the body, but for the patient to survive the cancer, it's often necessary to go through with the treatment anyway.

13 Dec 2021

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Scientists have recently reported the efficacy of carrageenan against both the SARS-CoV-2 original strain as well as the Alpha, Beta, Gamma, and Delta VOCs.

13 Dec 2021

New technology could help determine COVID-19 patients at risk for micro thrombosis-related issues

Physicians treating coronavirus infections have a new diagnostic that could help identify patients at risk of organ failure.

13 Dec 2021

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

A new study shows that the ACE2 and RBD of coronavirus spike fragments have different binding strengths and dissociation rates when they are glycosylated and non-glycosylated.

13 Dec 2021

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

COVID-19 in association with pre-existing mental and physical health issues

The present study attempts to identify the factors that increase the risk of COVID-19 infection or confer protection against COVID-19 in a study population above 55 years of age known to experience higher morbidity and risk of mortality from COVID-19.

13 Dec 2021

Cell News and Research

INTEGRA offers answers to your cell culture throughput needs

Vaccinated seropositive individuals are able to induce high anti-spike SIgA responses

Assay for the identification of SARS-CoV-2 Spike reactive T and B cells

Risk of SARS-CoV-2 reinfection in children compared to adults

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Omicron variant may strike double vaccinated

Lymphoma patients can benefit from early CAR T treatment, study shows

Determination of the effectiveness of COVID-19 vaccination using T cell receptor repertoire

Novel breathalyzer relies on viral RNA detection to diagnose SARS-CoV-2

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

Scientists describe dynamic genomic landscape of tumor heterogeneity in hepatocellular carcinoma

Study offers new hope for large B-cell lymphoma patients

Drug combination without chemotherapy can be effective in treating older patients with Ph+ ALL

Protein can protect the heart from damage following cancer treatment

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

New technology could help determine COVID-19 patients at risk for micro thrombosis-related issues

Glycans strengthen interaction between viral spike proteins and ACE2 receptors on host cells

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

COVID-19 in association with pre-existing mental and physical health issues

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