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New study: Periodontal therapy can help reduce medical costs for patients with diabetes

The results from a new CIGNA study support that there is a potential association between treated periodontal disease and reduced medical costs for patients with diabetes.

30 Mar 2011

Positive preliminary results from Presidio's PPI-461 Phase 1b trial against HCV

Presidio Pharmaceuticals, Inc. announced today positive preliminary results from a Phase 1b clinical trial of PPI-461, a novel HCV NS5A inhibitor for the treatment of patients with chronic hepatitis C.

30 Mar 2011

Pelvic arterial embolization therapy effective treatment for postpartum hemorrhage

Pelvic arterial embolization or PAE, a minimally invasive, life-saving therapy, is a safe and effective treatment for postpartum hemorrhage, say researchers at the Society of Interventional Radiology's 36th Annual Scientific Meeting in Chicago, Ill.

30 Mar 2011

Maternal childhood maltreatment can affect offspring's health

Mothers who were maltreated as children have increased risk for giving birth to low birth weight babies. The findings, by researchers at the University of Washington, are the first to show that maternal maltreatment can affect the health of offspring.

30 Mar 2011

BIOTRONIK completes patient enrollment in IN-TIME clinical trial to treat HF

BIOTRONIK SE & Co. KG, a leading manufacturer of cardiac devices, announced today that the last chronic heart failure patient was enrolled in IN-TIME at the Schwabing Clinic in Munich, Germany, with principle investigator Professor Stefan Sack, MD.

30 Mar 2011

Smoking withdrawal after liver transplantation may protect against neoplasia development

Spanish researchers have found that liver transplant recipients who quit smoking have a lower incidence of smoking-related malignancies than patients who keep smoking.

30 Mar 2011

Intercept initiates OCA FLINT trial in patients with nonalcoholic steatohepatitis

Intercept Pharmaceuticals, Inc., has been informed by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health that patient enrollment has started in a new clinical trial in patients with nonalcoholic steatohepatitis, which will evaluate Intercept's first-in-class farnesoid X receptor agonist obeticholic acid as a novel therapy for NASH.

30 Mar 2011

Natural disasters can produce major lung problems

A comprehensive new review published in the journal Respirology indicates that lung problems are major causes of morbidity and mortality following natural disasters.

29 Mar 2011

Smoking cessation after liver transplantation reduces incidence of malignancy

Spanish researchers have found that liver transplant recipients who quit smoking have a lower incidence of smoking-related malignancies (SRM) than patients who keep smoking. In fact, SRMs were identified in 13.5% of deceased patients and smoking was associated with a higher risk of malignancy in this study. Full findings are published in the April issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases.

29 Mar 2011

Onyx plans to expand carfilzomib Phase 3 European trial in patients with myeloma

Onyx Pharmaceuticals, Inc. today announced its plans to expand the Phase 3 European clinical trial FOCUS, which is evaluating the efficacy and tolerability of carfilzomib, a selective next-generation proteasome inhibitor.

29 Mar 2011

Viewpoints: 'Lesson' from R.I. on waivers; Wis. infant mortality rate disparities; diabetes and seniors

Medicaid is the major cost driver in state budgets these days, so several Governors have proposed a deal to the White House and Congress: They'll take less money in return for the flexibility to run the program with fewer federal strings. A case study in the potential benefits is coming from liberal Rhode Island.

29 Mar 2011

PHOENIX phase III trial of PHP for distributive shock to continue after positive midpoint recommendation from DMB

The PHOENIX trial is a European, placebo-controlled, Phase III study treating catecholamine-resistant patients in distributive shock with the Nitric Oxide (NO) scavenger Pyridoxalated Haemoglobin Polyoxyethylene Conjugate (PHP). The study was launched by Curacyte AG in Austria, Belgium, Germany, Spain, The Netherlands and in the United Kingdom in 2009.

28 Mar 2011

Early symptoms of Parkinson's disease may be revealed in dream sleep

During a large-scale study of the socioeconomic costs of this neurodegenerative disease, Danish researchers, some from the University of Copenhagen, discovered that very early symptoms of Parkinson's disease may be revealed in dream or REM sleep.

28 Mar 2011

Challenges of high-risk surgery

A small group of "high-risk" patients account for a disproportionately high number of surgery-related deaths, complications, and costs. The April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS), commences a special series on high-risk surgery—focusing on new and emerging strategies for identifying and managing patients at high risk.

28 Mar 2011

Cancer drug Gleevec may hold promise against scleroderma: Study

A drug approved to treat certain types of cancer has shown promising results in the treatment of patients with scleroderma, according to results from an open-label Phase II trial. While the drug's efficacy must be demonstrated in a Phase III trial, the gold standard for testing a drug, researchers are optimistic that Gleevec- (imatinib) could potentially be a weapon against the chronic connective tissue disease for which a treatment has remained elusive.

28 Mar 2011

Study finds surgeon availability linked to fewer MVC-related deaths

Researchers at the University of California, San Diego School of Medicine claim that the availability of surgeons is a critical factor in public health and suggest that surgery should become an important part of the primary health care system.

28 Mar 2011

Lupus nephritis ESRD study finds increase in incidence rates among children, African Americans

New research documenting changes in the incidence and outcomes of end-stage renal disease in the U.S. between 1995 and 2006, found a significant increase in incidence rates among patients 5 to 39 years of age and in African Americans.

28 Mar 2011

U.S. TB cases reach all-time low, but eradication target missed, CDC says

"The number of tuberculosis cases in the United States reached an all-time low last year, with only 11,181 cases reported to public health authorities, according to the Centers for Disease Control and Prevention," the Los Angeles Times' "Booster Shots" blog reports.

28 Mar 2011

CPRIT awards Bellicum $5.7 million to advance CaspaCIDe therapy for late stage cancer

Bellicum Pharmaceuticals, Inc. today announced that the Company received notice of a $5.7 million company commercialization award from the Cancer Prevention and Research Institute of Texas ("CPRIT"). Bellicum was the only company recommended for funding in this second round of the commercialization award program.

25 Mar 2011

U.S. statewide bank crises study finds no major impact of depression on mortality

A study published today provides a new perspective on the Great Depression of the 1930s. A widely held view is that there were remarkable improvements in life expectancy of over five years.

25 Mar 2011

Mortality News and Research

New study: Periodontal therapy can help reduce medical costs for patients with diabetes

Positive preliminary results from Presidio's PPI-461 Phase 1b trial against HCV

Pelvic arterial embolization therapy effective treatment for postpartum hemorrhage

Maternal childhood maltreatment can affect offspring's health

BIOTRONIK completes patient enrollment in IN-TIME clinical trial to treat HF

Smoking withdrawal after liver transplantation may protect against neoplasia development

Intercept initiates OCA FLINT trial in patients with nonalcoholic steatohepatitis

Natural disasters can produce major lung problems

Smoking cessation after liver transplantation reduces incidence of malignancy

Onyx plans to expand carfilzomib Phase 3 European trial in patients with myeloma

Viewpoints: 'Lesson' from R.I. on waivers; Wis. infant mortality rate disparities; diabetes and seniors

PHOENIX phase III trial of PHP for distributive shock to continue after positive midpoint recommendation from DMB

Early symptoms of Parkinson's disease may be revealed in dream sleep

Challenges of high-risk surgery

Cancer drug Gleevec may hold promise against scleroderma: Study

Study finds surgeon availability linked to fewer MVC-related deaths

Lupus nephritis ESRD study finds increase in incidence rates among children, African Americans

U.S. TB cases reach all-time low, but eradication target missed, CDC says

CPRIT awards Bellicum $5.7 million to advance CaspaCIDe therapy for late stage cancer

U.S. statewide bank crises study finds no major impact of depression on mortality

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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