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Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

In a new study, researchers developed a bioinformatics pipeline that uses RNA sequencing data to identify altered genes and signaling pathways affected by viral infection.

13 Dec 2021

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

In this study cohort, SARS-CoV-2 infections were confirmed via the RT-PCR test.

13 Dec 2021

Researchers develop a universal SARS-CoV-2 neutralizing antibody

A new study has been published in Frontiers in Immunology, where scientists developed a universal SARS-CoV-2 neutralizing antibody, MG1141A.

13 Dec 2021

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

A new mouse study found that intranasal administration of MV130 protected against severe acute respiratory syndrome coronavirus 2.

13 Dec 2021

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

Researchers from the Biological Defence Programme of Singapore have investigated six of these antibodies.

13 Dec 2021

SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

Researchers have been investigating the immune response in previously infected healthcare workers after they receive these vaccines.

13 Dec 2021

Genetic-code expansion technique to potentially create next-generation vaccine candidate

A new experiment devised a novel method to manipulate virulent viruses in conventional laboratories and validated the prophylactic effect of this method in two mouse models.

13 Dec 2021

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

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12 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

An assessment of COVID-19 mortality risk using patient biomarker time series

A new study discusses the use of multiple biomarkers taken over the course of hospitalization in COVID-19 patients to determine the risk of mortality.

12 Dec 2021

Autonomous genome annotation of SARS-CoV-2 genes, proteins and domains

In a new research paper, a group of scientists from various institutions offers a semi-supervised custom pipeline for annotating all SARS-CoV-2 genes, proteins, and functional domains.

12 Dec 2021

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Researchers deploy mutagenesis studies to investigate the relationship between ORF6 localization and IFN antagonism.

12 Dec 2021

Effect of mutations on SARS-CoV-2 E protein interactions with cell junctions

In a recent study, ten human PDZ-containing proteins showed significant interactions with the SARS-CoV-2 E protein in a PBM-dependent manner.

12 Dec 2021

Even if SARS-CoV-2 Omicron evades antibodies, immunity still exists

Researchers determined antibody-mediated neutralization efficacy against the authentic SARS-CoV-2 Omicron variant.

12 Dec 2021

New tool to help map immune escape with SARS-CoV-2 mutations

A new study discusses a computational program that can be used to substitute for actual experimental evidence of the biologic impact of new mutations.

12 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

Former diabetes drug may help in the treatment of breast cancer, study shows

Findings from a new study led by Yale Cancer Center show the small molecule inhibitor drug, PF05175157, originally developed to treat diabetes by Pfizer, may help in the treatment of breast cancer.

12 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

Cell News and Research

Bioinformatics pipeline can be used to quickly identify SARS-CoV-2 therapeutics

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

Researchers develop a universal SARS-CoV-2 neutralizing antibody

MV130 immunotherapy boosts natural and vaccine-induced SARS-CoV-2 immunity in mice

Cellular properties of SARS-CoV-2 spike protein RBD in virus-infected African green monkey kidney epithelial cells

SARS-CoV-2-specific T cell and antibody responses in healthcare workers that suffered from COVID-19 one year ago

Genetic-code expansion technique to potentially create next-generation vaccine candidate

A method to eliminate mutants in the furin cleavage site of SARS-CoV-2 in Calu-3 cells

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

An assessment of COVID-19 mortality risk using patient biomarker time series

Autonomous genome annotation of SARS-CoV-2 genes, proteins and domains

Study demonstrates SARS-CoV-2 ORF6 localization and interferon antagonism as independent events

Effect of mutations on SARS-CoV-2 E protein interactions with cell junctions

Even if SARS-CoV-2 Omicron evades antibodies, immunity still exists

New tool to help map immune escape with SARS-CoV-2 mutations

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

Former diabetes drug may help in the treatment of breast cancer, study shows

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

What are the challenges of cell line development? eBook

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