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Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects.

16 Dec 2016

Retinoblastoma protein plays larger role in tumor suppression, study finds

The Retinoblastoma protein (pRB) has long been studied for its role in cell growth and the prevention of cancer.

16 Dec 2016

Researchers explore kidney biomarkers to track lupus progression

Lupus, a chronic autoimmune disease, can wreak havoc on an affected individual's body through inflammation, pain and even damage of the skin, joints and organs.

16 Dec 2016

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, this cell type - far more than most cancer cells - encases its genetic messages in protein globs called "stress granules" that lessen the effect of chemotherapies.

16 Dec 2016

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

In a study published in the Journal of Lipid Research, Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels, as well as reduces body fat in an animal model.

16 Dec 2016

DuPont research project aims to enable global access for protein-based biologic medications

DuPont Industrial Biosciences today announced receipt of a grant from the Bill & Melinda Gates Foundation to support a new area of research. The research project, which commences immediately, aims to create new production systems to enable affordable, protein-based biologic medications, such as antibodies.

16 Dec 2016

Researchers develop new method to identify antigens for cancer treatment

New cancer therapies harness the immune system to fight tumors. One of the main principles behind these therapies is to find out precisely which molecules on cancer cells trigger an immune response.

16 Dec 2016

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

A chip developed by mechanical engineers at Worcester Polytechnic Institute can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient.

16 Dec 2016

Calcium channel blockers may be effective drugs against cancer metastasis

Researchers at the University of Turku, Finland have identified a new way of blocking the spread of cancer. Calcium channel blockers, which are used to lower blood pressure, block breast and pancreatic cancer invasion by inhibiting cellular structures.

16 Dec 2016

Microseeding could be potential method for overcoming hemihedral twinning in protein crystals

Twinning is a crystal-growth disorder in which the specimen is composed of distinct domains whose orientations differ but are related in a particular, well-defined way.

16 Dec 2016

UT Southwestern researchers develop new imaging method to see proteins in action

UT Southwestern Medical Center researchers developed a new imaging technique that makes X-ray images of proteins as they move in response to electric field pulses.

16 Dec 2016

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

E-cigarette vapour does not damage DNA, even at doses 28 times that of equivalent smoke exposure.

16 Dec 2016

Vitamin B3 may help treat preeclampsia-affected pregnant women

Scientists in Japan and the US have found that vitamin B3 nicotinamide may help treat pregnant women who suffer from preeclampsia by preventing strokes and in some cases, even stimulating the growth of their fetus.

15 Dec 2016

Researchers correct motor symptoms linked to Parkinson's disease in mice

A research group led by University of Helsinki Docent Timo Myöhänen has succeeded in correcting the motor symptoms associated with Parkinson's disease in mice.

15 Dec 2016

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

A Kobe University research team has pinpointed the mechanism underlying astrocyte-mediated restoration of brain tissue after an injury. This could lead to new treatments that encourage regeneration by limiting damage to neurons incurred by reduced blood supply or trauma.

15 Dec 2016

Western diet during pregnancy may increase obesity risk in offspring

Diet composition around the time of pregnancy may influence whether offspring become obese, according to a new study using animal models at The Scripps Research Institute (TSRI).

15 Dec 2016

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of chronic, joint-destroying rheumatoid arthritis (RA).

15 Dec 2016

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.

15 Dec 2016

People with protein in urine more likely to develop memory problems, dementia

People who have protein in their urine, which is a sign of kidney problems, may also be more likely to later develop problems with thinking and memory skills or even dementia, according to a meta-analysis published in the December 14, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

15 Dec 2016

New duo therapy offers hope for 'super blockage' of over-active immune system

A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.

15 Dec 2016

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G Protein News and Research

Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Retinoblastoma protein plays larger role in tumor suppression, study finds

Researchers explore kidney biomarkers to track lupus progression

Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

DuPont research project aims to enable global access for protein-based biologic medications

Researchers develop new method to identify antigens for cancer treatment

WPI researchers develop chip to trap and identify metastatic cancer cells in blood

Calcium channel blockers may be effective drugs against cancer metastasis

Microseeding could be potential method for overcoming hemihedral twinning in protein crystals

UT Southwestern researchers develop new imaging method to see proteins in action

Lab-based cellular tests reveal that e-cigarette vapour does not induce DNA damage

Vitamin B3 may help treat preeclampsia-affected pregnant women

Researchers correct motor symptoms linked to Parkinson's disease in mice

Researchers pinpoint mechanism underlying astrocyte-mediated recovery of brain tissue after injury

Western diet during pregnancy may increase obesity risk in offspring

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

People with protein in urine more likely to develop memory problems, dementia

New duo therapy offers hope for 'super blockage' of over-active immune system

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