Genetic Engineering News and Research

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Research findings raise hope for better treatment of diabetic wounds

Diabetics often have to contend with wounds that heal poorly. Researchers at the Max Planck Institute for Biology of Ageing, the CECAD Excellence Cluster and the Institute of Genetics of the University of Cologne have now gained fresh insights into the underlying cellular mechanisms.

12 Oct 2016

Study on common bacterium presents new pathway to combat gastric cancers

A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study led by University of Georgia researchers.

12 Oct 2016

Study finds new therapeutic target to prevent progression of rare blood cancer

In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice.

7 Oct 2016

Study provides insight into how the brain's biological clock regulates physiological function

The brain's biological clock stimulates thirst in the hours before sleep, according to a study published in the journal Nature by McGill University researchers.

6 Oct 2016

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate stubborn reservoirs of breast and ovarian cancer stem cells (CSCs).

4 Oct 2016

UEF research shows retinal changes may be detected earlier than brain changes

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye.

3 Oct 2016

Researchers discover potential new therapeutic target for treating obesity

Scientists at Baylor College of Medicine, the National Institutes of Health and Virginia Tech Carilion Research Institute have discovered a new mechanism in the mouse brain that regulates obesity.

3 Oct 2016

New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

There has been much recent excitement about immunotherapy and the use of genetically engineered chimeric antigen receptor (CAR) T cells.

30 Sep 2016

Research uncovers new clues to combat dengue and Zika virus

Structural biology research conducted at the U.S. Department of Energy's SLAC National Accelerator Laboratory has uncovered how small insecticidal protein crystals that are naturally produced by bacteria might be tailored to combat dengue fever and the Zika virus.

28 Sep 2016

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Imran Noorani MD, MRCS, of Cambridge, England, received the Brainlab Community Neurosurgery Abstract Award at the Congress of Neurological Surgeons Annual Meeting in San Diego.

28 Sep 2016

Scientists discover new switch that coordinates DNA repair and cell death

The genetic information of every cell is encoded in the sequence of the DNA double helix. Double strand breaks in the DNA, which can be induced by radiation, are a dangerous threat to the cells, and if not properly repaired can lead to cancer.

28 Sep 2016

Ludwig researchers shed more light on key requirement for function of regulatory T cells

A Ludwig Cancer Research study published online September 5th in Nature Immunology illuminates a key requirement for the function of regulatory T cells—immune cells that play a critical role in many biological processes, from suppressing inflammation and deadly autoimmunity to helping tumors evade immune attack.

23 Sep 2016

Common genetic variant reduces neurobiological benefits of exercise in mice

A new study revealed that a common genetic variant in the brain-derived neurotrophic factor gene reduces the neurobiological benefits induced by physical exercise in mice.

21 Sep 2016

Researchers identify mutant traits in mouse for many human disease genes

About one-third of all genes in the mammalian genome are essential for life. An international, multi-institutional research collaboration identified, for the first time, mutant traits in the mouse for 52 human disease genes, which significantly contributes to the understanding of the genetic bases for some human diseases, including cardiovascular defects, spina bifida, and metabolic disorders, among many others. The study was published this week in Nature.

19 Sep 2016

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

For the 25 percent of type-2 diabetes patients who suffer from numbness and extreme nerve pain in their feet, a new dermatological treatment being tested by Northwestern Medicine scientists could potentially help prevent and maybe even reverse the neuropathy.

13 Sep 2016

Research shows how placenta umpires fight for nutrients between pregnant mother and foetus

New research provides the first clear evidence that the amount of nutrients transported to the foetus by the placenta adjusts according to both the foetal drive for growth, and the mother's physical ability to provide.

13 Sep 2016

Researchers find innovative and cost-effective ways to remove PFAS from water supply

Elevated levels of perfluoroalkyl substances (PFASs) in drinking water can persist in water supplies for long periods and present an important health risk for millions of Americans, from hormone suppression to potentially cancer.

9 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Fruit flies hold clues to how cancerous tumors get started

A Florida State University research team, in coordination with a team from Japan, has found that the epithelial tissues that line the surfaces of organs throughout the body intrinsically have hot spots for cancerous tumors.

9 Sep 2016

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

A new study by the Translational Genomics Research Institute and Northern Arizona University used deep DNA sequencing methods to generate the anthrax genome sequence from the victims of the 1979 anthrax outbreak in Sverdlovsk, Russia, when it was part of the USSR.

9 Sep 2016

Genetic Engineering News and Research

Research findings raise hope for better treatment of diabetic wounds

Study on common bacterium presents new pathway to combat gastric cancers

Study finds new therapeutic target to prevent progression of rare blood cancer

Study provides insight into how the brain's biological clock regulates physiological function

HDAC inhibitors show potential to eliminate breast and ovarian cancer stem cells

UEF research shows retinal changes may be detected earlier than brain changes

Researchers discover potential new therapeutic target for treating obesity

New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

Research uncovers new clues to combat dengue and Zika virus

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Scientists discover new switch that coordinates DNA repair and cell death

Ludwig researchers shed more light on key requirement for function of regulatory T cells

Common genetic variant reduces neurobiological benefits of exercise in mice

Researchers identify mutant traits in mouse for many human disease genes

New dermatological treatment could potentially help prevent or reverse diabetic neuropathy

Research shows how placenta umpires fight for nutrients between pregnant mother and foetus

Researchers find innovative and cost-effective ways to remove PFAS from water supply

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Fruit flies hold clues to how cancerous tumors get started

Tgen-NAU researchers produce anthrax genome sequence from victims of 1979 outbreak

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