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BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Scientists from the Biogerontology Research Foundation (BGRF), a UK-based charity founded to support ageing research and address the challenges of a rapidly ageing population, propose a new concept for signalome-wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

19 Aug 2014

Targeting club cells may help shorten duration of flu symptoms

A specialized subset of lung cells can shake flu infection, yet they remain stamped with an inflammatory gene signature that wreaks havoc in the lung, according to a study published in The Journal of Experimental Medicine.

19 Aug 2014

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Researchers have long suspected that major mental disorders are genetically-rooted diseases of synapses - the connections between neurons.

18 Aug 2014

Individual’s genetic make-up determines effect of stress on emotional centres

Our individual genetic make-up determines the effect that stress has on our emotional centres. These are the findings of a group of researchers from the MedUni Vienna. Not every individual reacts in the same way to life events that produce the same degree of stress.

18 Aug 2014

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

A new study led by researchers at Brigham and Women's Hospital (BWH) and Rush University Medical Center, reveals how early changes in brain DNA methylation are involved in Alzheimer's disease.

18 Aug 2014

Scientists create computer algorithm for cell and tissue engineering

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

16 Aug 2014

Researchers study LDLR protein using new, groundbreaking techniques

Researchers from the Copenhagen Center for Glycomics at the University of Copenhagen have studied an important receptor protein called LDLR using new, groundbreaking techniques. The protein plays an important role in the absorption of the bad cholesterol, LDL.

16 Aug 2014

Illness-linked genetic variation affects connections among neurons in the developing brain

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports.

16 Aug 2014

Researchers now have a clear picture of bacterial immune system

Bacteria's ability to destroy viruses has long puzzled scientists, but researchers at the Johns Hopkins Bloomberg School of Public Health say they now have a clear picture of the bacterial immune system and say its unique shape is likely why bacteria can so quickly recognize and destroy their assailants.

15 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

Dyadic's net product related revenue for Q2 2014 increases 28% to $4.9 million

Dyadic International, Inc., a global biotechnology company whose patented and proprietary technologies are used to develop, manufacture and sell enzymes and other proteins for the bioenergy, bio-based chemical, biopharmaceutical and industrial enzyme industries, today announced financial results for the second quarter ended June 30, 2014.

14 Aug 2014

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

A modified version of the Clostridium novyi (C. novyi-NT) bacterium can produce a strong and precisely targeted anti-tumor response in rats, dogs and now humans, according to a new report from Johns Hopkins Kimmel Cancer Center researchers.

14 Aug 2014

Clinical trial tests COXEN model in bladder cancer to find promising treatment

Imagine being able to match a cancer's genes to the best treatment. That's the promise of COXEN (CO eXpression ExtrapolatioN) - a computer program that looks at a panel of cancer genes in a patient's tumor to predict whether it will respond to chemotherapy.

14 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Genes News and Research

BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Targeting club cells may help shorten duration of flu symptoms

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Individual’s genetic make-up determines effect of stress on emotional centres

Researchers reveal how early changes in DNA methylation involved in Alzheimer's disease

Scientists create computer algorithm for cell and tissue engineering

Researchers study LDLR protein using new, groundbreaking techniques

Illness-linked genetic variation affects connections among neurons in the developing brain

Researchers now have a clear picture of bacterial immune system

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

NTU research could lead to better treatment options for children suffering from leukaemia

Dyadic's net product related revenue for Q2 2014 increases 28% to $4.9 million

Modified C. novyi-NT bacterium produces precisely targeted anti-tumor response

Clinical trial tests COXEN model in bladder cancer to find promising treatment

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Ebola virus defeats attempts by interferon to block viral reproduction in infected cells

Scientists identify gene that regulates sleep and wake rhythms

Findings open up improved treatment possibilities for children suffering from leukaemia

Researchers make significant step forward in understanding mechanisms that cause leukaemia

Findings may lead to better ways for preventing gum disease, diabetes and Crohn's disease

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