Genes News and Research

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CRI researchers identify gene linked to several childhood cancers

Researchers at the Children-s Medical Center Research Institute at UT Southwestern have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to model the cancers.

11 Aug 2014

GW researcher awarded grant to develop a model system to study PN infection

According to a recent World Health Organization report of the leading causes of death worldwide, one-third of all deaths are due to infectious and parasitic diseases. There are currently no vaccines for parasitic nematode (PN), or worm infections in humans, and development of new drugs and vaccines will stall until researchers have a better understanding of PN biology.

11 Aug 2014

Patient with mechanical heart pump receives new gene therapy for heart failure

For the first time in the world, a patient with a mechanical heart pump has received a new gene therapy for heart failure at Harefield Hospital, London.

11 Aug 2014

Scientists find new clues to early detection, personalised treatment of ovarian cancer

Scientists at A*STAR's Institute of Medical Biology and the Bioinformatics Institute have found new clues to early detection and personalised treatment of ovarian cancer, currently one of the most difficult cancers to diagnose early due to the lack of symptoms that are unique to the illness.

9 Aug 2014

Researchers awarded $3.3 million NIH grant to study role of genetics in protecting against frailty

Frailty is a common condition associated with old age, characterized by weight loss, weakness, decreased activity level and reduced mobility, which together increase the risk of injury and death. Yet, not all elderly people become frail; some remain vigorous and robust well into old-age.

8 Aug 2014

Individuals with work related stress are at higher risk of developing type 2 diabetes

Workplace stress can have a range of adverse effects on health with an increased risk of cardio-vascular diseases in the first line.

8 Aug 2014

Scientists solve key mystery in cancer research

A chance meeting between two leading UK and US scientists could have finally helped solve a key mystery in cancer research.

8 Aug 2014

Researchers find that animal's ability to endure internal parasite strongly influences reproductive success

In the first evidence that natural selection favors an individual's infection tolerance, researchers from Princeton University and the University of Edinburgh have found that an animal's ability to endure an internal parasite strongly influences its reproductive success.

8 Aug 2014

Notch signaling also plays important role in onset of obesity and Type 2 diabetes

A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment.

8 Aug 2014

Molecule Notch involved in fear memory formation

Nature is thrifty. The same signals that embryonic cells use to decide whether to become nerves, skin or bone come into play again when adult animals are learning whether to become afraid.

7 Aug 2014

Secret of aging skin may lie in glycan and micronutrient creams

For decades, dermatologists have been researching the genetic cause of aging skin so that the perfect antidote could be developed. When examining genes and proteins, a difference between younger and older looking skin has not been found.

7 Aug 2014

Mutations in CTR9 gene cause rare cases of Wilms tumour in children

Mutations in a gene that helps regulate when genes are switched on and off in cells have been found to cause rare cases of Wilms tumour, the most common kidney cancer occurring in children.

7 Aug 2014

Study sheds light on genetic alterations that may contribute to luminal B breast cancer

Researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine have uncovered new information about the genetic alterations that may contribute to the development of a subtype breast cancer typically associated with more aggressive forms of the disease and higher recurrence rates.

7 Aug 2014

Discovery lays groundwork for new class of antibiotics for Staphylococcus aureus infections

St. Jude Children's Research Hospital scientists have discovered an enzyme that regulates production of the toxins that contribute to potentially life-threatening Staphylococcus aureus infections. The study recently appeared in the scientific journal the Proceedings of the National Academy of Sciences.

7 Aug 2014

MIT researchers generate liver tumors in adult mice

Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw — but breeding such mice is an expensive, time-consuming process.

7 Aug 2014

UCSF researchers identify novel molecular features within the developing human brain

UC San Francisco researchers have identified cells' unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.

7 Aug 2014

Findings show how galectin-1 protein plays key role in high grade malignant gliomas

Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, new research shows.

7 Aug 2014

Twin study supports psychosis continuum

A study of adolescent twins suggests that similar factors influence psychotic experiences regardless of their severity, consistent with a psychosis continuum.

6 Aug 2014

Comprehensive database collecting information about microRNAs, multiMiR

Your genes are blueprints for proteins, and molecules called microRNA can help to determine how often these genetic blueprints are manufactured into proteins. Researchers often ask what microRNA regulates a gene related to disease.

6 Aug 2014

Researchers develop new methods to identify genes important for survival of MRSA in pigs

It is important to keep the number of MRSA infections at a low level. In a PhD project at the National Food Institute, Technical University of Denmark, the latest technologies within whole genome sequencing were exploited to develop new methods to identify genes which are important for the survival of MRSA in pigs.

5 Aug 2014

Genes News and Research

CRI researchers identify gene linked to several childhood cancers

GW researcher awarded grant to develop a model system to study PN infection

Patient with mechanical heart pump receives new gene therapy for heart failure

Scientists find new clues to early detection, personalised treatment of ovarian cancer

Researchers awarded $3.3 million NIH grant to study role of genetics in protecting against frailty

Individuals with work related stress are at higher risk of developing type 2 diabetes

Scientists solve key mystery in cancer research

Researchers find that animal's ability to endure internal parasite strongly influences reproductive success

Notch signaling also plays important role in onset of obesity and Type 2 diabetes

Molecule Notch involved in fear memory formation

Secret of aging skin may lie in glycan and micronutrient creams

Mutations in CTR9 gene cause rare cases of Wilms tumour in children

Study sheds light on genetic alterations that may contribute to luminal B breast cancer

Discovery lays groundwork for new class of antibiotics for Staphylococcus aureus infections

MIT researchers generate liver tumors in adult mice

UCSF researchers identify novel molecular features within the developing human brain

Findings show how galectin-1 protein plays key role in high grade malignant gliomas

Twin study supports psychosis continuum

Comprehensive database collecting information about microRNAs, multiMiR

Researchers develop new methods to identify genes important for survival of MRSA in pigs

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