Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study reveals how B cells react to SARS-CoV-2

In an exciting immunological medRxiv preprint paper, researchers from Germany and Russia analyzed adaptive immune response in severely affected patients with coronavirus disease (COVID-19). They demonstrated a protracted immune reaction characterized by egress of B lymphocytes into the blood.

9 Sep 2020

Researchers receive $1.9 million federal grant to find Lyme disease vaccine

Pesky, yet dangerous ticks are no longer latching exclusively onto hunters and outdoor enthusiasts. Milder winters and disrupted habitats have driven them out of the woods, with Lyme disease cases in the United States tripling since the late 1990s.

9 Sep 2020

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers in the United States and Germany have conducted a study demonstrating the preclinical efficacy of a new candidate vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

9 Sep 2020

Researchers discover a new way to limit inflammation from adjuvants in vaccines

Adjuvants are a key ingredient of many modern vaccines, working to unleash an immune response that helps protect the body from disease. Many scientists believe that adjuvants are they key to developing new kinds of vaccines for hard-to-vaccinate viruses, like HIV.

9 Sep 2020

Common diabetes drug controls aspects of inflammation in mice

The diabetes drug metformin--derived from a lilac plant that's been used medicinally for more than a thousand years--has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes.

9 Sep 2020

Scientists shed new light on gene regulatory pathways activated by stress hormone

Scientists have long known that chronic stress experienced early in life, or even chronic prenatal exposure to maternal stress hormones in the womb, can shorten lifespan and contribute to age-related chronic diseases like arthritis, asthma, cancer, cardiovascular disease, diabetes and even mental illness later in life -- long after the source of stress has been removed.

9 Sep 2020

Protein aggregation reduces elasticity of blood vessels in the brain

Deposits of a protein called "Medin", which manifest in virtually all older adults, reduce the elasticity of blood vessels during aging and hence may be a risk factor for vascular dementia.

9 Sep 2020

Exploring the Relationship Between Mass Spectrometry and Informatics

Mass spectrometry has always had a powerful synergy with computers. Computers have pushed mass spectrometry forward at key junctures in it’s history from data collection to instrument operation to data analysis.

From Bruker Daltonics 9 Sep 2020

Host gene editing main driving force of SARS-CoV-2 mutations

A new study published on the aRxiv preprint server in September 2020 shows that the host immune response, mediated by two RNA editors, causes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to adapt and change strain characteristics.

9 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

Across 5 days in August (3rd-7th), scientists from around the world gathered virtually to present and discuss new information on the role of the chemical senses in disease, nutrition, and social interactions in humans and animals.

9 Sep 2020

'Molecular brake' on the immune system could be potential treatment target for severe COVID-19

Older people and people with underlying medical conditions are at particular risk of severe COVID-19. A group of researchers from Charité - Universitätsmedizin Berlin have discovered one possible reason for this vulnerability.

8 Sep 2020

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

A targeted therapy called capmatinib can provide significant benefits to patients who have advanced lung cancer with specific gene mutations, according to recently published results from a phase two clinical trial.

8 Sep 2020

Scientists develop a rapid, reliable and low-cost COVID-19 antibody test

Robust and widespread antibody testing has emerged as a key strategy in the fight against SARS-CoV-2, the virus responsible for the COVID-19 pandemic.

8 Sep 2020

Study reveals complex immunology behind MIS-C in children with COVID-19

In a recent paper published in the prestigious journal Cell, researchers from Sweden and Italy show that inflammatory response in Multisystem Inflammatory Syndrome in Children associated with coronavirus disease (COVID-19) differs from the cytokine storm found in severe acute illness, involving autoantibodies at the same time and sharing several features with Kawasaki disease.

8 Sep 2020

Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

Science-based technology company 3M has awarded a significant philanthropic research grant of $400,000 to the Shmunis School of Biomedicine and Cancer Research at Tel Aviv University to advance scientific knowledge in the global response to the COVID-19 pandemic.

8 Sep 2020

The T cell responses in COVID-19 recovered individuals

A recent study demonstrates that functional CD4+ and CD8+ T cells specifically targeting the entire proteome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain active in individuals who have recovered from severe or mild coronavirus disease 2019 (COVID-19). Moreover, the magnitude of T cell response is correlated with the antibody response. The study is published in the journal Nature Immunology.

8 Sep 2020

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

An investigational drug that targets an instigator of the TDP-43 protein, a well-known hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), may reduce the protein's buildup and neurological decline associated with these disorders, suggests a pre-clinical study from researchers at Penn Medicine and Mayo Clinic.

8 Sep 2020

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Patients hospitalized with severe COVID-19 infections who have high levels of the blood clotting protein factor V are at elevated risk for serious injury from blood clots such as deep vein thrombosis or pulmonary embolism, investigators at Massachusetts General Hospital (MGH) have found.

8 Sep 2020

Acne drug could be a potential treatment for dilated cardiomyopathy

Dilated cardiomyopathy (DCM) is a leading cause of heart failure, affecting 1 in 250 people. The disease is characterised by an increase in size of the left ventricle of the heart.

8 Sep 2020

Protein News and Research

Further Reading

Study reveals how B cells react to SARS-CoV-2

Researchers receive $1.9 million federal grant to find Lyme disease vaccine

Pfizer, BioNTech COVID-19 vaccine candidate shows promise in preclinical study

Researchers discover a new way to limit inflammation from adjuvants in vaccines

Common diabetes drug controls aspects of inflammation in mice

Scientists shed new light on gene regulatory pathways activated by stress hormone

Protein aggregation reduces elasticity of blood vessels in the brain

Exploring the Relationship Between Mass Spectrometry and Informatics

Host gene editing main driving force of SARS-CoV-2 mutations

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

Researchers discuss the role of chemical senses in disease and social interactions in humans, animals

'Molecular brake' on the immune system could be potential treatment target for severe COVID-19

Targeted therapy can provide benefits to lung cancer patients with specific gene mutations

Scientists develop a rapid, reliable and low-cost COVID-19 antibody test

Study reveals complex immunology behind MIS-C in children with COVID-19

Tel Aviv University receives philanthropic grant from 3M for COVID-19 vaccine research

The T cell responses in COVID-19 recovered individuals

Investigational drug may reduce protein buildup and neurological decline linked to ALS, FTD

High levels of blood clotting factor V in severe COVID‐19 associated with worse outcomes

Acne drug could be a potential treatment for dilated cardiomyopathy

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