Genes News and Research

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Study shows inactivation of p53 protein promotes cancer progression

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona have discovered the interaction between HERC2 proteins with another protein called p53 that is inactivated in more than half of human tumors.

22 Jul 2014

Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

Viruses designed to target and kill cancer cells could boost the effectiveness of chemotherapy to the arms and legs and help avoid amputation, a new study reports.

22 Jul 2014

ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

ROS1 fusion genes were successfully detected independent of gender or smoking history in young East Asian patients with lung adenocarcinoma, a histological subgroup in non-small cell lung cancer (NSCLC), using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC) diagnostic tests.

22 Jul 2014

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

Porvair Sciences has developed a new ChIP sequencing assay kit extending the benefits of their proprietary Chromatrap® solid state ChIP technology to preparation of purified Chromatin for the generation of sequencing libraries.

From Chromatrap® - Porvair Sciences Ltd 22 Jul 2014

Epigenetic test helps eliminate unnecessary repeat prostate biopsies

More than one million prostate biopsies are performed each year in the U.S. alone, including many repeat biopsies for fear of cancer missed. Therefore there is a need to develop diagnostic tests that will help avoid unnecessary repeat biopsies.

22 Jul 2014

Researchers uncover new schizophrenia gene links

The discovery of over a hundred genetic risk factors linked to schizophrenia provides vital new clues in understanding what causes the condition and will kick-start the search for new treatments, according to leading UK scientists.

22 Jul 2014

First diagnostic criteria proposed for Christianson Syndrome

Because the severe autism-like condition Christianson Syndrome was only first reported in 1999 and some symptoms take more than a decade to appear, families and doctors urgently need fundamental information about it. A new study that doubles the number of cases now documented in the scientific literature provides the most definitive characterization of CS to date.

22 Jul 2014

Findings point to biological mechanisms and pathways that may underlie schizophrenia

As part of a multinational, collaborative effort, researchers from the University of North Carolina School of Medicine and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in what is the largest genomic study published on any psychiatric disorder to date.

22 Jul 2014

New insights into biology of bread wheat genome

Bread wheat (Triticum aestivum L.) is the most widely cultivated cereal crop in the world and provides 20 percent of the food calories consumed by humans.

22 Jul 2014

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

The natural DNA bases that form the letters of DNA are usually referred to as G, C, A, and T. Those are only the first letters of the chemical names. They’re often called nucleotides by their scientific name and all of them have in common a phosphate part, a sugar part and a nucleobase part.

21 Jul 2014

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

The New York State Department of Health (DOH) has granted Roswell Park Cancer Institute (RPCI) approval to begin genomic testing of cancer patients using its OmniSeq TargetTM advanced molecular diagnostic laboratory test.

21 Jul 2014

Genomics testing in action: an interview with Kevin Haar, CEO, Appistry

The more connections are made between genes, disease and drugs, and the more that we continue to understand about those connections, the more critical genetic testing will become in modern medicine.

21 Jul 2014

Study of woodrats may impact farming practices in arid regions

Woodrats lost their ability to eat toxic creosote bushes after antibiotics killed their gut microbes. Woodrats that never ate the plants were able to do so after receiving fecal transplants with microbes from creosote-eaters, University of Utah biologists found.

21 Jul 2014

Scientists reveal structure of protein involved in life and development of cancer

Scientists reveal the structure of one of the most important and complicated proteins in cell division - a fundamental process in life and the development of cancer - in research published in Nature today (Sunday).

21 Jul 2014

Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

A team of scientists from around the world led by Baylor College of Medicine and Washington University in St. Louis has completed the genome sequence of the common marmoset - the first sequence of a New World Monkey - providing new information about the marmoset's unique rapid reproductive system, physiology and growth, shedding new light on primate biology and evolution.

21 Jul 2014

Study: Genetics plays major role in development of autism

Using new statistical tools, Carnegie Mellon University's Kathryn Roeder has led an international team of researchers to discover that most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

21 Jul 2014

Researchers develop new single-cell technique to study environmental effects on DNA

Researchers at the BBSRC-funded Babraham Institute, in collaboration with the Wellcome Trust Sanger Institute Single Cell Genomics Centre, have developed a powerful new single-cell technique to help investigate how the environment affects our development and the traits we inherit from our parents.

21 Jul 2014

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

A multi-disciplinary team of scientists from the National Cancer Centre Singapore, Duke-NUS Graduate Medical School Singapore, and Singapore General Hospital have made a seminal breakthrough in understanding the molecular basis of fibroadenoma, one of the most common breast tumours diagnosed in women.

21 Jul 2014

New study explores processes that establish connections between nerve cells in the brain

New research provides an intriguing glimpse into the processes that establish connections between nerve cells in the brain. These connections, or synapses, allow nerve cells to transmit and process information involved in thinking and moving the body.

19 Jul 2014

Scientists identify genes that may help predict steroid responsiveness in people with EoE

Results from a clinical trial show that high doses of the corticosteroid fluticasone propionate safely and effectively induce remission in many people with eosinophilic esophagitis (EoE), a chronic inflammatory disease of the esophagus characterized by high levels of white blood cells called eosinophils.

19 Jul 2014

Genes News and Research

Study shows inactivation of p53 protein promotes cancer progression

Viruses designed to kill cancer cells could boost effectiveness of chemotherapy to arms, legs

ROS1 fusion genes found in young East Asian patients with lung adenocarcinoma

New chromatin immunoprecipitation sequencing kit developed by Porvair Sciences

Epigenetic test helps eliminate unnecessary repeat prostate biopsies

Researchers uncover new schizophrenia gene links

First diagnostic criteria proposed for Christianson Syndrome

Findings point to biological mechanisms and pathways that may underlie schizophrenia

New insights into biology of bread wheat genome

Unnatural DNA bases: an interview with Professor Floyd E. Romesberg, The Scripps Research Institute

New York State DOH grants RPCI approval to begin genomic testing of cancer patients

Genomics testing in action: an interview with Kevin Haar, CEO, Appistry

Study of woodrats may impact farming practices in arid regions

Scientists reveal structure of protein involved in life and development of cancer

Marmoset's unique rapid reproductive system sheds new light on evolution and primate biology

Study: Genetics plays major role in development of autism

Researchers develop new single-cell technique to study environmental effects on DNA

Scientists make seminal breakthrough in understanding molecular basis of fibroadenoma

New study explores processes that establish connections between nerve cells in the brain

Scientists identify genes that may help predict steroid responsiveness in people with EoE

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