Genes News and Research

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Learning role of immune-system cells in digestive tracts may lead to new treatments for IBS

Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS).

18 Jul 2014

Researchers receive nearly $3.6 million to create new National Clinical Trials Network

A team of physician-researchers from Huntsman Cancer Institute (HCI) at the University of Utah (U of U) has received nearly $3.6 million over the next five years in a cooperative agreement with the National Institutes of Health (NIH) to establish a Network Lead Academic Participating Site (NLAPS).

18 Jul 2014

IWGSC publishes draft sequence of bread wheat genome

The International Wheat Genome Sequencing Consortium (IWGSC) published today in the international journal Science a draft sequence of the bread wheat genome.

18 Jul 2014

Study illustrates how domino effect of one genetic error can contribute to hydrocephalus

The mysterious condition once known as "water on the brain" became just a bit less murky this week thanks to a global research group led in part by a Case Western Reserve researcher.

18 Jul 2014

Role of immune system cells in healthy digestive tracts may lead to new treatments for IBS

Learning the role of immune system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS).

18 Jul 2014

Signaling pathway key player in formation of front-most portion of developing vertebrate embryos

A signaling pathway once thought to have little if any role during embryogenesis is a key player in the formation of the front-most portion of developing vertebrate embryos.

18 Jul 2014

Doctor maps path of discovery for developing potential anticancer agent

The journal Cancer Cell today published research led by Dr. Tak Mak mapping the path of discovery to developing a potential anticancer agent.

18 Jul 2014

Starvation can affect health of descendants of famished individuals

Evidence from human famines and animal studies suggests that starvation can affect the health of descendants of famished individuals. But how such an acquired trait might be transmitted from one generation to the next has not been clear.

18 Jul 2014

Splice-switching oligonucleotide drugs alter editing of gene transcript

In splice-switching, an innovative therapeutic approach, targeted oligonucleotide drugs alter the editing of a gene transcript to produce the desired form of a protein.

18 Jul 2014

Scientists find single gene that plays surprising role in manipulating aging

It is something of an eternal question: Can we slow or even reverse the aging process? Even though genetic manipulations can, in fact, alter some cellular dynamics, little is known about the mechanisms of the aging process in living organisms.

18 Jul 2014

Lipoic acid appears to reset and synchronize circadian rhythms

Researchers have discovered a possible explanation for the surprisingly large range of biological effects that are linked to a micronutrient called lipoic acid: It appears to reset and synchronize circadian rhythms, or the "biological clock" found in most life forms.

18 Jul 2014

Researchers make significant breakthrough that may benefit patients with bowel cancer

Researchers at Queen's University have made a significant breakthrough that may benefit patients with bowel cancer.

18 Jul 2014

Single injection of protein FGF1 enough to restore blood sugar levels

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days.

17 Jul 2014

Scientists sequence genome of Asian liver fluke, a cancer-causing parasite

Scientists have sequenced the genome and characterised the genes of the Asian liver fluke, Opisthorchis viverrini. This parasite causes diseases that affect millions of people in Asia and is associated with a fatal bile duct cancer.

16 Jul 2014

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

The basic idea of cancer chemoprevention is to arrest or reverse the progression of premalignant cells towards full malignancy, using physiological mechanisms that do not kill healthy cells.

16 Jul 2014

Study finds that friends who are not biologically related still resemble each other genetically

If you consider your friends family, you may be on to something. A study from the University of California, San Diego, and Yale University finds that friends who are not biologically related still resemble each other genetically.

16 Jul 2014

Researchers reveal molecular interplay between Roquin and RNA

The Roquin protein, discovered in 2005, controls T-cell activation and differentiation by regulating the expression of certain mRNAs. In doing so, it helps to guarantee immunological tolerance and prevents immune responses against the body's own structures that can lead to autoimmune disease.

16 Jul 2014

Fatty acid transport proteins genetically linked to schizophrenia and ASD

Using diverse methodologies, neuroscientists from the RIKEN Brain Science Institute report that defects in Fatty Acid Binding Proteins (FABPs) may help to explain the pathology in some cases of schizophrenia and autism spectrum disorders.

16 Jul 2014

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Mount Sinai Heart at Icahn School of Medicine at Mount Sinai has been awarded a $3.8 million grant by the American Heart Association to promote cardiovascular health among high-risk New York City children, and their parents, living in Harlem and the Bronx. With assistance from the NYC Administration for Children's Services, the research team's mission is to reduce each child's future risk of obesity, heart attack, stroke, and type 2 diabetes.

16 Jul 2014

Research reveals why HIV remains a long-lasting infection

HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children's Research Institute, University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells.

16 Jul 2014

Genes News and Research

Learning role of immune-system cells in digestive tracts may lead to new treatments for IBS

Researchers receive nearly $3.6 million to create new National Clinical Trials Network

IWGSC publishes draft sequence of bread wheat genome

Study illustrates how domino effect of one genetic error can contribute to hydrocephalus

Role of immune system cells in healthy digestive tracts may lead to new treatments for IBS

Signaling pathway key player in formation of front-most portion of developing vertebrate embryos

Doctor maps path of discovery for developing potential anticancer agent

Starvation can affect health of descendants of famished individuals

Splice-switching oligonucleotide drugs alter editing of gene transcript

Scientists find single gene that plays surprising role in manipulating aging

Lipoic acid appears to reset and synchronize circadian rhythms

Researchers make significant breakthrough that may benefit patients with bowel cancer

Single injection of protein FGF1 enough to restore blood sugar levels

Scientists sequence genome of Asian liver fluke, a cancer-causing parasite

Chemoprevention and colon cancer: an interview with Dr. John Letterio, Case Western Reserve University School of Medicine

Study finds that friends who are not biologically related still resemble each other genetically

Researchers reveal molecular interplay between Roquin and RNA

Fatty acid transport proteins genetically linked to schizophrenia and ASD

Mount Sinai awarded AHA grant to prevent heart disease among NYC children and parents

Research reveals why HIV remains a long-lasting infection

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