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Researchers reveal key role of bacteria-binding protein in intestine

Deficiency in a certain protein in the gastrointestinal tract has been shown to lead to both inflammation and abdominal fat accumulation in mice.

8 Dec 2016

Researchers discover biological pathway that plays vital role in tumor development

An international team led by researchers from the Technion-Israel Institute of Technology's Rappaport Faculty of Medicine and the Technion Integrated Cancer Center has discovered a biological pathway that plays an important role in tumor development.

7 Dec 2016

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

While new targeted treatments developed across the past two decades have led to dramatic survival improvements for women with HER2-positive metastatic breast cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators report that rates of breast cancer brain metastasis for women with this disease have not substantially declined.

7 Dec 2016

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits

Scientists from the Florida campus of The Scripps Research Institute have made an important discovery toward the development of drugs to treat age-related memory loss in diseases like Alzheimer's.

7 Dec 2016

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Inherited pathogenic variants in protein coding genes BARD1 and RAD51D increase a woman's likelihood of developing breast cancer, according to research conducted at Mayo Clinic and presented today at the 2016 San Antonio Breast Cancer Symposium.

7 Dec 2016

Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Scientists have found a way to detect earlier if a deadly cancer, Merkel cell carcinoma (MCC), is recurring in patients, according to a paper to be published 11 a.m. Eastern time, Dec. 7, in the journal Cancer.

7 Dec 2016

Study shows involvement of lipid metabolism in tumour metastasis

A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine, and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36.

7 Dec 2016

Brazilian researchers propose new way for treating thalassemia major

Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean anemia.

7 Dec 2016

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Two genetic mutations known to play a role in many solid cancers might also help explain why a subset of acute myeloid leukemia (AML) patients develop the disease, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

7 Dec 2016

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

In a new study, researchers have modified a rabies virus, so that it has a protein from the MERS virus; this altered virus works as a 2-for-1 vaccine that protects mice against both Middle East Respiratory Syndrome (MERS) and rabies.

7 Dec 2016

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Misfolded proteins associated with Parkinson's disease were detected in cerebrospinal fluid by scientists at McGovern Medical School at The University of Texas Health Science Center at Houston, paving the way to development of a biochemical test to diagnosis the disease.

7 Dec 2016

Vaxine’s unique adjuvants boost effectiveness of vaccines for battling against infectious diseases

SUGAR-based adjuvants from Australia are boosting the effectiveness of vaccines to target some of the world’s deadliest diseases.

7 Dec 2016

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

A common class of drugs for vision loss may actually add to the problem in some patients, according to new research co-led by scientists at The Scripps Research Institute (TSRI).

7 Dec 2016

Researchers report supportive care for cancer patients remains insufficient

Pain relief and other forms of supportive care for cancer patients are insufficient, researchers report at the ESMO ASIA 2016 Congress in Singapore.

7 Dec 2016

New study suggests how risk gene linked to ADHD may work

Genetics play a strong part in the development of attention-deficit/hyperactivity disorder (ADHD), but the path from a gene to risk for the disorder has remained a black box to researchers.

7 Dec 2016

Scientists discover how motors maneuver cells' intricate roadway system

Much like motors power our cars, they also ensure that proteins get to the right place in our cells, and a wide variety of diseases - from cancer to heart problems - can result when they don't.

7 Dec 2016

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

The biomarker PD-1, a protein, could potentially be used to predict survival or disease-free survival of lung cancer patients who have had the tumour surgically removed.

6 Dec 2016

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

Led by Prof. Mohamed Lamkanfi (VIB-Ghent University), researchers have demonstrated in animal models that a protein called NLRP2 plays an important role in early embryogenesis, the process of cell division in fertilized eggs that occurs before they implant into the lining of the uterus.

6 Dec 2016

New UTMB study sheds light on how Ebola effectively disables immune system

A new study at The University of Texas Medical Branch in Galveston sheds light on how Ebola so effectively disables the human immune system.

6 Dec 2016

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

Imagine a key that opens a pin tumbler lock. A very similar key can also fit into the lock, but upside down in comparison to the first key.

6 Dec 2016

G Protein News and Research

Researchers reveal key role of bacteria-binding protein in intestine

Researchers discover biological pathway that plays vital role in tumor development

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

TSRI scientists identify potential therapeutic target for age- or Alzheimer's disease-related memory deficits

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

Scientists find novel way for earlier detection of deadly Merkel cell carcinoma

Study shows involvement of lipid metabolism in tumour metastasis

Brazilian researchers propose new way for treating thalassemia major

New research reveals role of two genetic mutations in subset of acute myeloid leukemia

Researchers create 2-for-1 vaccine that protects mice from MERS and rabies

New discovery paves way to development of biochemical test for diagnosing Parkinson's disease

Vaxine’s unique adjuvants boost effectiveness of vaccines for battling against infectious diseases

TSRI scientists reveal how vision-loss treatment may leave the eyes, kidneys vulnerable to cellular damage

Researchers report supportive care for cancer patients remains insufficient

New study suggests how risk gene linked to ADHD may work

Scientists discover how motors maneuver cells' intricate roadway system

PD-1 protein could serve as biomarker for predicting survival of lung cancer patients

VIB scientists reveal how NLRP2 protein plays key role in early embryogenesis and fertility

New UTMB study sheds light on how Ebola effectively disables immune system

Biochemists uncover how potential diabetes drugs interact with LRH-1 protein

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