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Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Human immune system proteins can help combat chlamydia infections

Scientists from Federal Research and Clinical Centre of Physical-Chemical Medicine, Koltzov Institute of Developmental Biology and MIPT have shown that peptidoglycan recognition proteins (PGLYRPs) of the human immune system can play a key role in the fight against chlamydia infections. Their study was published in Infection and Immunity.

28 Jul 2016

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold.

28 Jul 2016

Yale researchers develop new system to simultaneously edit multiple genes

A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects.

26 Jul 2016

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Every five minutes someone in the U.S. dies from a blood clot, through its role in strokes, heart attacks or other severe conditions.

26 Jul 2016

New technology allows researchers to temporarily shut down brain area to better understand function

Capitalizing on experimental genetic techniques, researchers at the California National Primate Research Center, or CNPRC, at the University of California, Davis, have demonstrated that temporarily turning off an area of the brain changes patterns of activity across much of the remaining brain.

22 Jul 2016

Researchers identify important therapeutic target for small cell lung cancer

UT Southwestern Medical Center researchers have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.

22 Jul 2016

Study highlights effectiveness of atypical antipsychotic drug in treating children with TD

A meta-analysis of clinical trials evaluating the effectiveness of aripiprazole for the treatment of Tourette's disorder (TD) in children and adolescents showed a significantly greater overall improvement in total tics and tic severity from pretreatment to post-treatment for the aripiprazole compared to the placebo group.

21 Jul 2016

Researchers identify how sensory nerve receptors work together to transmit itch signals

Researchers have found how sensory nerve cells work together to transmit itch signals from the skin to the spinal cord, where neurons then carry those signals to the brain. Their discovery may help scientists find more effective ways to make itching stop.

20 Jul 2016

Biochemists design genetic poison pill to thwart coxsackievirus B3

It has a funny name - coxsackievirus - but there's nothing funny about how this tiny germ and its close relatives sicken their hosts.

18 Jul 2016

New treatment may destroy HIV's last refuge

UK scientists may have found a way to destroy HIV's last refuge. A study by Oxford University has confirmed that a treatment developed by a British company can remove the virus in its chosen hiding place, in laboratory conditions, offering hope of a viable treatment.

15 Jul 2016

Researchers find immune system directly affects, controls social behavior

In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects - and even controls - creatures' social behavior, such as their desire to interact with others.

14 Jul 2016

AAPS Foundation announces winner of 2016 New Investigator Grant

The AAPS Foundation is pleased to announce the 2016 New Investigator Grant recipient, Yizhou Dong, Ph.D of the Ohio State University, for his research entitled "Development of nonviral gene-engineering delivery systems".

14 Jul 2016

Gut microbiota could influence person's likelihood of developing colon cancer

The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person's likelihood of developing colon cancer.

13 Jul 2016

Scientists use machine learning to interpret mosquito genome

Scientists are using machine learning to identify important sequences of DNA within the mosquito genome that regulate how the insect's cells develop and behave.

12 Jul 2016

Factors linked to sexual victimization risk among college students

Sexual victimization on college campuses may be more or less likely depending on institutional characteristics of the school such as size, type (public or private), sex ratio, selectivity, and percentage of students involved in Greek life (fraternities and sororities).

12 Jul 2016

Diversity of gut bacteria may affect brain health

The surprising and potentially wide-ranging effects that the levels and diversity of bacteria living in the gut have on overall human health, inflammation, and specifically brain health are the focus of a provocative interview with Dr. David Perlmutter in Alternative and Complementary Therapies, a journal from Mary Ann Liebert, Inc., publishers.

11 Jul 2016

New study suggests potential role for gut microbiota in diabetes remission after bypass surgery

Studies have shown that bariatric surgery can lead to remission of type 2 diabetes mellitus (T2DM) in rodents and humans, but this beneficial effect cannot be explained solely by weight loss.

11 Jul 2016

Researchers aim to explore impact of gender and aging on CapZ levels in the heart

Why do women have lower rates of heart failure than men for most of their lives? University of Guelph researchers have uncovered a possible clue - an actin binding protein called "CapZ" that also protects against heart attacks.

7 Jul 2016

Review examines role of gut microbes in development, progression of MS

An increasing number of clinical studies are pointing to a link between the autoimmune disease multiple sclerosis (MS) and the composition of microbes in the human gut, sparking new research on the gut microbiome as a potential target for MS treatment and prevention.