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XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "XRCC1: a potential prognostic and immunological biomarker in LGG based on systematic pan-cancer analysis."

30 Jan 2024

Weight loss in people with type 2 diabetes can change cancer-related proteins

A weight loss intervention in people with type 2 diabetes was found to alter levels of cancer-related proteins, according to the findings of a new University of Bristol-led study.

30 Jan 2024

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

30 Jan 2024

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

There are many lingering mysteries from the COVID-19 pandemic. For instance, why does SARS-CoV-2, the virus behind the disease, cause severe symptoms in some patients, while many other coronaviruses don't? And what causes strange symptoms to persist even after the infection has been cleared from a person's system?

30 Jan 2024

Overcoming stigma to start early conversations about cognitive decline

Approximately four of five primary care clinicians consider themselves on the front lines of brain health.

30 Jan 2024

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

29 Jan 2024

Teen substance use tied to higher rates of depression, anxiety, and suicidal thoughts

High school students who reported using cannabis, alcohol, or nicotine were more likely to have thoughts about suicide, feel depressed or anxious, have unusual experiences, and exhibit inattention or hyperactivity, according to recent survey-based study conducted by researchers at Massachusetts General Hospital (MGH) and the University of Minnesota.

29 Jan 2024

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

27 Jan 2024

Female reproductive characteristics may be overlooked as risk factors for later metabolic dysfunction

A new review of available evidence led by researchers at the Harvard Pilgrim Health Care Institute suggests that female reproductive characteristics may be overlooked as risk factors that contribute to later metabolic dysfunction.

27 Jan 2024

Study reveals dramatic decreases in emergency contraception related ER visits over 14 year period

Following federal approval for over the counter emergency contraception in 2006, emergency departments across the U.S. saw dramatic decreases in related visits and medical charges, a new study suggests.

27 Jan 2024

Washington University School of Medicine joins collaboration to improve pediatric heart disease care

Washington University School of Medicine in St. Louis has joined the Pediatric Heart Network, a multicenter collaboration of leading hospitals and research institutions that works to improve care for pediatric heart disease patients.

25 Jan 2024

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

A single dose of the typhoid conjugate vaccine, Typbar TCV, provides lasting efficacy in preventing typhoid fever in children ages 9 months to 12 years old, according to a new study conducted by researchers at University of Maryland School of Medicine's (UMSOM) Center for Vaccine Development and Global Health (CVD) and led by in-country partners at the Malawi-Liverpool Wellcome Trust (MLW) Clinical Research Programme.

25 Jan 2024

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Over 700 million people were infected and almost seven million died, making SARS-CoV-2 the most devastating pandemic of the 21st century.

25 Jan 2024

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

The Icahn School of Medicine at Mount Sinai has been awarded a grant of more than $4 million from The Leona M. and Harry B. Helmsley Charitable Trust to support an innovative research project aimed at understanding the early stages of Crohn's disease before noticeable symptoms develop.

25 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

Genomics meets retinal imaging: A powerful fusion can predict future health

The retina is said to provide a window into a person's systemic health. In a new study published January 24th in Science Translational Medicine, physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, and the Broad Institute of MIT and Harvard combined retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future.

24 Jan 2024

Functional, nonepileptic seizures linked to higher death rate than expected

The death rate for patients with functional, nonepileptic seizures is higher than expected, with a rate comparable to epilepsy and severe mental illness, a Michigan Medicine-led study finds.

24 Jan 2024

Unintentional weight loss linked to increased risk of cancer diagnosis

Unintentional weight loss is associated with an increase in the risk of a cancer diagnosis within the coming year, according to a study from Dana-Farber Cancer Institute.

23 Jan 2024

Novel software measures the significance of specific genomic biomarkers to help predict diseases

IntelliGenes, a first of its kind software created at Rutgers Health, combines artificial intelligence (AI) and machine-learning approaches to measure the significance of specific genomic biomarkers to help predict diseases in individuals, according to its developers.

23 Jan 2024

Medical School News and Research

XRCC1 shows potential as a prognostic and immunological pan-cancer biomarker

Weight loss in people with type 2 diabetes can change cancer-related proteins

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

"Zombie" viral fragments trigger inflammation to cause serious COVID-19 outcomes

Overcoming stigma to start early conversations about cognitive decline

Oncofetal ecosystems linked to recurrence and immunotherapy response in liver cancer

Teen substance use tied to higher rates of depression, anxiety, and suicidal thoughts

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

Female reproductive characteristics may be overlooked as risk factors for later metabolic dysfunction

Study reveals dramatic decreases in emergency contraception related ER visits over 14 year period

Washington University School of Medicine joins collaboration to improve pediatric heart disease care

Clinical study supports the long-lasting impacts of typhoid conjugate vaccine

Researchers discover "protective switches" that shield the coronavirus from immune system attacks

Mount Sinai project receives $4M grant to understand the early stages of Crohn's disease

Study shows effectiveness of gene therapy in treating congenital deafness

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

Genomics meets retinal imaging: A powerful fusion can predict future health

Functional, nonepileptic seizures linked to higher death rate than expected

Unintentional weight loss linked to increased risk of cancer diagnosis

Novel software measures the significance of specific genomic biomarkers to help predict diseases

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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