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Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be used to deliver targeted medicines to human muscle cells.

12 May 2022

Nerve gas sarin largely responsible for Gulf War illness, study shows

For three decades, scientists have debated the underlying cause of Gulf War illness (GWI), a collection of unexplained and chronic symptoms affecting veterans of the Persian Gulf War.

12 May 2022

New research reveals a potent weapon against Parkinson's disease

Neurodegenerative diseases damage and destroy neurons, ravaging both mental and physical health. Parkinson's disease, which affects over 10 million people worldwide, is no exception.

11 May 2022

Telltale signs of concussions may be found in the gut, study suggests

A recently published study by Houston Methodist scientists suggests telltale signs of concussions might be found in the gut.

10 May 2022

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

An international team of researchers, led by scientists at University of California San Diego School of Medicine, report that a gene therapy that inhibits targeted nerve cell signaling effectively reduced neuropathic pain with no detectable side effects in mice with spinal cord or peripheral nerve injuries.

9 May 2022

Healthy Mediterranean diet helps young men to beat depression

Depression is a common mental health condition that affects approximately 1 million Australians each year. It is a significant risk factor for suicide, the leading cause of death in young adults.

9 May 2022

Single-cell-resolution map of retinal pigment epithelium could help develop precise therapies for degenerative diseases

Researchers have identified distinct differences among the cells comprising a tissue in the retina that is vital to human visual perception.

6 May 2022

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

It's often said that a little stress can be good for you. Now scientists have shown that the same may be true for cells, uncovering a newly-discovered mechanism that might help prevent the build-up of tangles of proteins commonly seen in dementia.

6 May 2022

New insights into the cellular and molecular mechanisms of absence seizures

Bochum researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options.

4 May 2022

Understanding dysphagia symptoms after spine surgery can help improve patients' quality of life

Difficulty swallowing is one of the most common complications of anterior cervical spine surgery (ACSS).

3 May 2022

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

Certain childhood tumors have an extreme need for amino acids. Scientists at the Hopp Children's Cancer Center Heidelberg (KiTZ), the German Cancer Research Center (DKFZ), the University of Heidelberg, and HI-STEM gGmbH have now discovered the molecular mechanisms underlying this and how the cancer cells could be turned off.

28 Apr 2022

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Spinal cord stimulation (SCS) for chronic pain involves delivering low levels of electricity directly into the spinal cord using an implanted device, which modifies or blocks nerve activity to minimize the sensation of pain reaching the brain.

28 Apr 2022

Scientists identify the neural basis of pleasant touch sensation

Studying mice, scientists at Washington University School of Medicine in St. Louis have identified a neural circuit and a neuropeptide - a chemical messenger that carries signals between nerve cells - that transmit the sensation known as pleasant touch from the skin to the brain.

28 Apr 2022

Researchers create 3D in vitro model that reveals the origins of human spine

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots. Defects in its development are known to cause rare hereditary diseases.

28 Apr 2022

Research shows existence of a link between atherosclerotic plaques and the central nervous system

A new research shows the existence of a connection between atherosclerotic plaques and the central nervous system.

27 Apr 2022

Glucose-lowering treatments may be effective in improving response to exercise training

Exercise carries a long list of benefits for everyone. For people with metabolic diseases like pre-diabetes, type 1 diabetes and type 2 diabetes, physical activity can help keep blood sugar levels in check and stave off diabetes-related nerve damage and heart disease.

25 Apr 2022

Researchers identify brain areas that control the ability to perform complex, sequential movements

In a novel set of experiments with mice trained to do a sequence of movements and "change course" at the spur of the moment, Johns Hopkins scientists report they have identified areas of the animals' brains that interact to control the ability to perform complex, sequential movements, as well as to help the mice rebound when their movements are interrupted without warning.

21 Apr 2022

Novel methods for inferring the movement of brain cells during fetal development

The making of a human brain remains a mostly mysterious process that races from an embryonic neural tube to more than 100 billion interconnected neurons in the brain of a newborn. To achieve this marvel of biological engineering, the developing fetal brain must grow, on average, at a rate of roughly 250,000 nerve cells per minute throughout the course of a pregnancy.

21 Apr 2022

Scientists demonstrate a new mechanism by which amino acids curb appetite

Proteins can suppress appetite, so a protein-rich diet can help people lose weight. That's just one of the reasons why this kind of diet has become increasingly popular in recent years.

20 Apr 2022

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.

19 Apr 2022

Nerve News and Research

Nanobodies from llamas could be used to deliver targeted medicines to human muscle cells

Nerve gas sarin largely responsible for Gulf War illness, study shows

New research reveals a potent weapon against Parkinson's disease

Telltale signs of concussions may be found in the gut, study suggests

Gene therapy effectively reduces neuropathic pain in mice with spinal cord injuries

Healthy Mediterranean diet helps young men to beat depression

Single-cell-resolution map of retinal pigment epithelium could help develop precise therapies for degenerative diseases

Newly-discovered mechanism may help prevent the build-up toxic proteins in dementia

New insights into the cellular and molecular mechanisms of absence seizures

Understanding dysphagia symptoms after spine surgery can help improve patients' quality of life

Researchers discover molecular mechanisms underlying extreme need for amino acids in neuroblastoma

High-frequency spinal cord stimulation proves to be more effective at improving perceived pain reduction

Scientists identify the neural basis of pleasant touch sensation

Researchers create 3D in vitro model that reveals the origins of human spine

Research shows existence of a link between atherosclerotic plaques and the central nervous system

Glucose-lowering treatments may be effective in improving response to exercise training

Researchers identify brain areas that control the ability to perform complex, sequential movements

Novel methods for inferring the movement of brain cells during fetal development

Scientists demonstrate a new mechanism by which amino acids curb appetite

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

Industry Focus eBook - Cell biology (5th edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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