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Study uncovers the regulator of cancer ‘stemness’

The protein FOXK2 promotes survival of cancer stem cells in ovarian cancer, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

26 Apr 2022

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Researchers developed a highly pathogenic mouse-adapted SARS-CoV-2 strain to model mild, moderate, or COVID-19.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

MGH investigators find important regulators of urinary concentration in the kidney

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood.

25 Apr 2022

Vaccine effectiveness against COVID-19 infection and related hospitalization

Researchers assessed the effectiveness of COVID-19 vaccines against COVID-19 infections and related hospitalizations.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Booster vaccine provides similar protection in SARS-CoV-2 naive and convalescent individuals

Researchers estimate the effectiveness of primary vaccination and a booster dose in people with and without prior SARS-CoV-2 infection.

24 Apr 2022

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Researchers explore how the presence of SARS-CoV-2 RNA in feces can be associated with the presentation of GI symptoms.

24 Apr 2022

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

Anti-N antibodies may have lower sensitivity in mRNA-1273-vaccinated individuals who were previously infected with SARS-CoV-2.

24 Apr 2022

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Researchers investigated variations in the host immune response-elicited by non-structural protein 1 of coronaviruses.

22 Apr 2022

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Researchers demonstrated SARS-CoV-2 evolution at the transcriptional level.

22 Apr 2022

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

Antibody-based treatment, endogenous immune responses, and within-host SARS-CoV-2 evolution in immunocompromised patients

Researchers investigated the interplay of all the factors responsible for within-host evolution of SARS-CoV-2 variants in immunocompromised patients.

21 Apr 2022

Transcription News and Research

Study uncovers the regulator of cancer ‘stemness’

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

A novel mouse model to test SARS-CoV-2 viral infection

Researchers develop new platform capable of mitochondrial DNA editing

MGH investigators find important regulators of urinary concentration in the kidney

Vaccine effectiveness against COVID-19 infection and related hospitalization

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

The challenges of Omicron

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Booster vaccine provides similar protection in SARS-CoV-2 naive and convalescent individuals

4% patients with COVID-19 shed fecal viral RNA 10 months after diagnosis

Impact of COVID-19 vaccination on anti-nucleocapsid antibody levels

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

COVID-19 mRNA vaccine protects against ICU admission for 1 year

SARS-CoV-2 spike protein disrupts lipid metabolism resulting in liver, heart & kidney damage

Researchers discover potential targets for treating perivascular fibrosis

Antibody-based treatment, endogenous immune responses, and within-host SARS-CoV-2 evolution in immunocompromised patients

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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