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Protein in the blood could predict type 2 diabetes many years before diagnosis

A large study led by Lund University in Sweden has identified a protein in the blood that could predict type 2 diabetes up to nineteen years before the onset of the disease.

11 Nov 2021

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Northwestern University investigators have developed a new injectable therapy that harnesses "dancing molecules" to reverse paralysis and repair tissue after severe spinal cord injuries.

11 Nov 2021

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Researchers have been investigating which other proteins remain prevalent long enough for tests against them to be worthwhile.

11 Nov 2021

New Delta sublineage shows no additional resistance to neutralization

Researchers are attempting to determine the ability of this new sublineage to avoid neutralization by antibodies elicited from vaccination.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

New target for drug development could fill a major gap in depression treatment

Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects.

10 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Immune checkpoint inhibitor therapy results in longer treatment-free survival for patients with advanced renal cell carcinoma

Patients with advanced renal cell carcinoma who received the checkpoint inhibitor combination nivolumab (Opdivo) plus ipilimumab (Yervoy) experienced longer treatment-free survival (TFS) over a 42-month period than patients who received the targeted therapy sunitinib (Sutent), regardless of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) risk group, according to new analysis of the CheckMate-214 clinical trial.

10 Nov 2021

Researchers discover mechanisms underlying the unwanted side effects of drugs

Researchers at Weill Cornell Medicine have discovered how drugs can affect various membrane-spanning proteins in addition to their intended target, potentially causing unwanted side effects.

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021