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Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Aastrom Biosciences, Inc., a leading developer of expanded autologous cellular therapies for the treatment of severe cardiovascular diseases, today announced that an interim analysis of all 86 patients enrolled in the company's Phase 2b RESTORE-CLI clinical trial shows that the study achieved both its primary safety endpoint and primary efficacy endpoint of time to first occurrence of treatment failure.

19 Nov 2010

Multiple epidemiological parameters drive increase in drug-treatment opportunities for pancreatic cancer: Decision Resources

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds significant trends in multiple epidemiological parameters to be driving the increase in drug-treatment opportunities for pancreatic cancer over the period 2009 to 2024, including population aging, increasing risk of recurrence following resection and modest improvements in survival.

18 Nov 2010

Urgent action needed to address urban health inequities

A new report published today by WHO and the United Nations Human Settlements Programme (UN-HABITAT) shows for the first time how ill-health is linked to poverty in cities, and not just among the poorest urban populations. It calls for policymakers to take action targeting health inequities.

18 Nov 2010

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

Exelixis, Inc. today reported interim data from the cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with XL184 in an ongoing phase 2 adaptive randomized discontinuation trial (RDT).

18 Nov 2010

PTSD doubles veteran's risk of death

Post-traumatic stress disorder (PTSD) more than doubles a veteran's risk of death from any cause and is an independent risk factor for cardiovascular disease, according to research presented at the American Heart Association's Scientific Sessions 2010.

18 Nov 2010

Vitamin C can prevent and reverse sepsis

Physicians caring for patients with sepsis may soon have a new safe and cost-effective treatment for this life-threatening illness. Research led by Dr. Karel Tyml and his colleagues at The University of Western Ontario and Lawson Health Research Institute have found that vitamin C can not only prevent the onset of sepsis, but can reverse the disease.

18 Nov 2010

Study shows end-of-life care varies widely

A new study released by the Dartmouth Atlas of Health Care finds that "America's hospitals treat patients with life-ending cancers very differently in their final months, with some deploying chemotherapy and other life-prolonging efforts until the end and others directing most of their patients into hospice," reports Kaiser Health News. The aggressive care may not be best for patients, and hospice may be a "more humane way to die," the report argues. A point the report doesn't address: that aggressive treatment "also adds to the drain on Medicare's pocketbook."

18 Nov 2010

AACN endorses intraosseous vascular access

Recognizing that IV use is not always optimal to provide patients with fluids and medications, the American Association of Critical-Care Nurses (AACN) recently endorsed a consensus paper that recommends intraosseous (IO) vascular access in a variety of healthcare settings.

17 Nov 2010

School vending machines influence dietary intake of students

Vending machines in public schools influence the diets of school children and can affect overall dietary intake and health, depending on what foods they contain.

17 Nov 2010

Cardiac surgery leads to stroke, seizure and neurological complications: Report

Strokes, seizures and other neurological complications related to heart surgery account for "considerable morbidity and mortality," Loyola University Health System neurologists report in the November issue of the journal Hospital Practice.

17 Nov 2010

NT-proBNP guided heart failure care associated with reduced cardiovascular events

Roche and study investigators from Harvard University and Massachusetts General Hospital announced today that in the PROTECT (Pro-BNP Outpatient Tailored Chronic HF Therapy) trial, a strategy of NT-proBNP guided heart failure care was independently associated with a significant reduction in total cardiovascular events, the primary composite endpoint of the study, which included worsening heart failure, heart failure hospitalization and cardiovascular related death

From Roche Sequencing and Life Science 17 Nov 2010

HealthGrades evaluates nation's top-performing hospitals in organ transplantation

HealthGrades, the nation's leading independent ratings organization, today made available to organ transplant patients a list of those hospitals with the best track record for survival and chances of receiving a donor organ. HealthGrades annual evaluation of the nation's top-performing hospitals in organ transplantation includes clinical quality data, based on patient outcomes, for each of the 210 adult acute care hospitals that perform transplants.

17 Nov 2010

Infinity announces enrollment in IPI-926 Phase 1b/2 clinical trial for pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced that enrollment is ongoing locally for a Phase 1b/2 clinical trial of IPI-926, Infinity's oral molecule that inhibits Smoothened, a key component of the Hedgehog pathway, in combination with Gemzar (gemcitabine) in patients with previously untreated, metastatic pancreatic cancer.

17 Nov 2010

Pre-term births are leading cause of health problems in infants and cost the U.S. over $26 billion annually

The Center for Healthcare Research & Transformation (CHRT) based at the University of Michigan today released its Prematurity Issue Brief that shows pre-term births --- births at less than 37 weeks of gestation --- are the leading cause of health problems in infants and estimated to cost the U.S. more than $26 billion annually. In addition, the report shows that a black infant in Michigan is 70% more likely to be born prematurely than an infant of any other race.

17 Nov 2010

National Medical Center specialist wins best abstract for Outstanding Research Award in Pediatric Cardiology

David Wessel, MD, senior vice president for Hospital-Based Specialties at Children's National Medical Center, won the best abstract for Outstanding Research Award in Pediatric Cardiology by the American Heart Association's Council on Cardiovascular Disease in the Young.

17 Nov 2010

Study reveals true effects of malaria on African generations

Almost a third of cerebral malaria survivors developed epilepsy or other behavioral disorders in the most comprehensive study to date of the disease in African children, solidifying the link between malaria and neuropsychiatric disorders that affect hundreds of thousands of children.

17 Nov 2010

TRITON–TIMI 38 substudy shows prasugrel reduces overall mortality rate in ACS patients

New results from an observational substudy from TRITON–TIMI 38 presented today at the American Heart Association (AHA) Scientific Sessions annual meeting showed that patients treated with Efient/Effient (prasugrel) prior to coronary artery bypass graft surgery (CABG) had a reduced overall mortality rate compared to patients treated with Plavix (clopidogrel)

17 Nov 2010

Neurologic complications remain an important cause of morbidity and mortality after heart surgeries

16 Nov 2010

National campaign to highlight significance of antibiotic resistance

Antibiotic resistance is one of the world's most pressing public health threats. To bring attention to this increasing problem, the Centers for Disease Control and Prevention and other government partners will observe its third annual Get Smart About Antibiotics Week on Nov. 15-21, 2010.

16 Nov 2010

As VA touts quality of system, study shows no difference in mortality rate

The Department of Veterans Affairs has touted for years the achievements of its health-care system, but a new study, published in the journal Medical Care, shows its health outcomes are about like everybody else's.

16 Nov 2010

Mortality News and Research

Aastrom announces interim analysis of Phase 2b RESTORE-CLI clinical trial for treatment failure

Multiple epidemiological parameters drive increase in drug-treatment opportunities for pancreatic cancer: Decision Resources

Urgent action needed to address urban health inequities

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

PTSD doubles veteran's risk of death

Vitamin C can prevent and reverse sepsis

Study shows end-of-life care varies widely

AACN endorses intraosseous vascular access

School vending machines influence dietary intake of students

Cardiac surgery leads to stroke, seizure and neurological complications: Report

NT-proBNP guided heart failure care associated with reduced cardiovascular events

HealthGrades evaluates nation's top-performing hospitals in organ transplantation

Infinity announces enrollment in IPI-926 Phase 1b/2 clinical trial for pancreatic cancer

Pre-term births are leading cause of health problems in infants and cost the U.S. over $26 billion annually

National Medical Center specialist wins best abstract for Outstanding Research Award in Pediatric Cardiology

Study reveals true effects of malaria on African generations

TRITON–TIMI 38 substudy shows prasugrel reduces overall mortality rate in ACS patients

Neurologic complications remain an important cause of morbidity and mortality after heart surgeries

National campaign to highlight significance of antibiotic resistance

As VA touts quality of system, study shows no difference in mortality rate

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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