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Link between SARS-CoV-2 organotropism and kidney injury

It was clear at a relatively early stage of the pandemic that SARS-CoV-2 causes a wide range of symptoms; in addition to typical respiratory symptoms, patients also had neurological symptoms (starting with anosmia), gastrointestinal symptoms, elevated liver values, and renal, urinary or hematological changes, for example.

8 Jun 2021

Researchers develop promising stem cell therapy to treat type 1 diabetes

Type 1 diabetes, which arises when the pancreas doesn't create enough insulin to control levels of glucose in the blood, is a disease that currently has no cure and is difficult for most patients to manage.

8 Jun 2021

Reduced use of convalescent plasma associated with higher COVID-19 mortality rate

A new study from researchers at Johns Hopkins Bloomberg School of Public Health and colleagues suggests a slowdown in the use of convalescent plasma to treat hospitalized COVID-19 patients led to a higher COVID-19 mortality during a critical period during this past winter's surge.

8 Jun 2021

New blood test helps monitor patient’s response to cancer treatment

Cancer patients who are undergoing targeted therapy can look forward to a new blood test that could tell their doctors whether the treatment is working, within one day after the start of the treatment.

8 Jun 2021

Study reports safety, efficacy of targeted treatment for IgA nephropathy

IgA nephropathy (IgAN) is a chronic kidney disease occurring in young adults and is one of the most common reasons for kidney transplantation in this age group.

7 Jun 2021

Study uncovers novel molecular mechanism of immune cell migration

In a new study, researchers from Osaka University discovered a novel molecular mechanism by which immune cells migrate to fight off infections. These findings may help in understanding the development of certain immune deficiency disorders and establish novel therapies against them.

7 Jun 2021

New research identifies protein as therapeutic anti-viral target for COVID-19

New research identified a novel interaction between the SARS-CoV-2 spike protein and the galectin-3-binding protein (LGALS3BP) which could be a new therapeutic anti-viral target.

7 Jun 2021

Measuring how patterns of gene expression change in children may help predict T1D progression

Type 1 diabetes (T1D) is an autoimmune disease in which a misdirected immune system gradually destroys healthy pancreatic islet β cells, resulting in a lack of insulin.

7 Jun 2021

COVID-19 can cause long-term consequences for the kidneys

The kidneys are a target organ of COVID-19 and are affected very early in the course. However, this is precisely where there is strong prognostic potential: As early as last spring, COVID-19-associated nephritis was identified as an early warning signal for severe courses of the infectious disease and studies to that effect were published.

7 Jun 2021

Experimental monoclonal antibody could be a new weapon against HIV epidemic

An experimental, lab-made antibody can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows.

7 Jun 2021

Discovery offers a potential new pathway to treat hypertension

High blood pressure, or hypertension, is the leading modifiable risk factor for cardiovascular diseases and premature death worldwide.

7 Jun 2021

Minimally-invasive procedure could offer hope to patients with high blood pressure

A minimally-invasive procedure that targets the nerves near the kidney has been found to significantly reduce blood pressure in hypertension patients, according to the results of a global multicentre clinical trial led in the UK by researchers at Queen Mary University of London and Barts Health NHS Trust.

7 Jun 2021

Study finds high levels of lead in indigenous people in Peruvian Amazonia

Lead is a toxic metal, and its widespread use has led to significant environmental pollution and public health problems in many parts of the world.

7 Jun 2021

Study observes broad and invariable memory B cell response following SARS-CoV-2 infection

A new study by researchers at the Oregon Health & Science University (OHSU) in the USA goes far in answering this question by showing the presence of memory B cells that react to the original SARS-CoV-2 as well as VOCs.

7 Jun 2021

Around 5% of children develop long COVID-19 symptoms, suggests new study

A new study, by researchers at University College London (UCL) in the UK, shows that even though children rarely develop symptomatically severe COVID-19, the prevalence of long COVID in children with a history of infection is over 4.5%.

7 Jun 2021

Could sustained inflammation following mild to moderate COVID-19 be a driver of long COVID?

A new study describes the discovery of sustained though low-level rises in inflammatory mediators and immune cells, as well as the loss of some subsets of naïve un-activated cells. This may indicate a widespread though muted immune-mediated inflammatory response in these patients.

7 Jun 2021

Kawasaki disease in children has reduced during COVID-19 due to pandemic prevention efforts

The rate of Kawasaki disease in South Korea has substantially decreased during the COVID-19 pandemic, possibly due to pandemic prevention efforts, such as mask-wearing, hand-washing and physical distancing, according to new research published today in the American Heart Association's flagship journal Circulation.

7 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Healthy habits of pregnancy – latest science show maternal habits affect pregnancy success

Four new studies investigating the effects of supplements, eating habits and physical activity and how they can affect various aspects of health during pregnancy are being presented at NUTRITION 2021 LIVE ONLINE.

7 Jun 2021

MRI-guided focused ultrasound advances brain and cancer research

By 2034, nearly one-quarter of Americans will have reached retirement age, according to the United States Census Bureau. But as people age, the brain becomes more susceptible to developing disorders, such as essential tremor, Parkinson's disease, and tumors.

7 Jun 2021