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Lung cancer in smokers versus non-smokers shows different genetic mutations

A group of scientists at B.C. Cancer Agency have found that lung cancers in smokers have different genetic mutations and look different than lung cancer in non-smokers. According to senior scientist at the BC Cancer Agency Research Centre Wan Lam, this finding is significant because it means that from now on, research, treatments and diagnostics should be tailored to the distinct genetic variations in the different lung cancers instead of expecting that a one-size fits all approach will work. He said, “At the current time, treatment does not distinguish between these different types. The subtypes are all grouped together. But with this work, we are beginning to tease out the subtypes.” The study was presented Tuesday at a conference in Philadelphia of the American Association of Cancer Research.

10 Nov 2010

Study finds no association between working in wafer fabrication cleanrooms, cancer mortality

An exhaustive, five-year epidemiological study conducted by researchers from Vanderbilt University covering more than 100,000 semiconductor industry workers found no association between overall cancer mortality and working in wafer fabrication cleanrooms, the Semiconductor Industry Association reported today.

10 Nov 2010

Hospitals need to work more to prevent heart attack deaths: Study

Door-to-balloon time has dropped dramatically as hospitals rush heart attack patients into treatment, but a five-year study released Monday shows quicker hospital care has not saved more lives.

10 Nov 2010

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

The 22nd annual conference of The MacLean Center for Clinical Medical Ethics at the University of Chicago will be held at the University of Chicago Law School, 1111 E. 60th Street, on Fri., Nov. 12, from 1 to 5 pm, and Sat., Nov. 13, from 7:30 am to 5:15 pm.

10 Nov 2010

Regional workshop to discuss diarrheal disease solutions for Asia

Each year, diarrheal disease claims the lives of 1.3 million children under five worldwide and hospitalizes millions more. The vast majority of these deaths occur in developing countries of Asia and Africa, but fortunately, interventions exist that can greatly reduce deaths and save lives. To bring attention to the solutions available today for defeating diarrhea, the Vietnam Ministry of Health, the National Pediatric Hospital of Vietnam, and PATH are hosting a two-day regional workshop where they will present the evidence and lessons learned from initiatives currently underway.

10 Nov 2010

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Women being treated for breast cancer with aromatase inhibitors may experience extremely low estrogen levels resulting in a wide variety of side effects that a typical postmenopausal woman without cancer may not experience.

10 Nov 2010

Silence Therapeutics' Atu027 RNAi drug prevents pulmonary metastasis formation

Silence Therapeutics plc announces positive research findings demonstrating the ability of the Company's lead RNA interference (RNAi) drug candidate, Atu027, to prevent the formation of pulmonary metastasis in various animal models of cancer metastasis. Researchers showed that Atu027 inhibited multiple key biological processes that enable and contribute to the dissemination and formation of pulmonary metastases in a murine breast cancer metastasis model.

10 Nov 2010

Investigations examine Medicare’s dialysis system, CT scanners and drugs

ProPublica reports on the costs and risks associated with dialysis: "In 1972, after a month of deliberation, Congress launched the nation's most ambitious experiment in universal health care: a change to the Social Security Act that granted comprehensive coverage under Medicare to virtually anyone diagnosed with kidney failure, regardless of age or income.

10 Nov 2010

Undergraduate students win Gates Foundation grant for low-cost ultrasound system

A team of University of Washington undergraduate students was among 65 research groups that today learned they had won one of the Bill & Melinda Gates Foundation's $100,000 Grand Challenges Explorations grants.

10 Nov 2010

$Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer$

Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer

Men with history of fracture and comorbidities are at an increased risk of fracture after long-term use of androgen deprivation therapy, and initiating this therapy should be carefully considered in older men with localized prostate cancer.

9 Nov 2010

Study demonstrates preventive effect of urate lowering therapy on cardiovascular mortality

The use of urate lowering therapy might successfully prevent death from cardiovascular disease in people with gout, according to research presented at the Nov 2010, American College of Rheumatology Annual Scientific Meeting in Atlanta.

9 Nov 2010

Mobile technology improves diagnosis and treatment for mothers, newborns and children

Simple mobile technology, like basic cell phones, can be used to save the lives of mothers in childbirth, and improve the care of newborns and children, reaching underserved populations in remote areas.

9 Nov 2010

Intercell aggregate revenues decrease 28.4% to EUR 21.1m in 9 months ended September 30, 2010

Today, Intercell AG announced its financial results for the third quarter of 2010 and presented an update on the Company's key R&D programs as well as changes to the Management Board.

9 Nov 2010

Statins do not reduce risk for colorectal cancer in postmenopausal women

The use of statins among a group of postmenopausal women did not reduce the risk for colorectal cancer, according to the results of a prospective analysis of data from the large population-based Women's Health Initiative (WHI).

9 Nov 2010

New data on Soliris for PNH treatment to be presented at ASH Annual Meeting

Alexion Pharmaceuticals, Inc. today announced that researchers are scheduled to present new data relating to Soliris (eculizumab) as a treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH) during the 52nd Annual Meeting of the American Society of Hematology (ASH), to be held December 4 - 7, 2010 at the Orange County Convention Center in Orlando.

9 Nov 2010

Officials discuss HIV/AIDS in Caribbean during PANCAP meeting

"Despite the gains associated with antiretroviral treatments (ART) over the last decade, HIV/AIDS remains the leading cause of death among young and middle-aged adults in the Caribbean, warns a new U.N. report" that was released during the 10th Annual General Meeting of the Pan Caribbean Partnership Against HIV and AIDS (PANCAP) that concluded on Tuesday, Inter Press Service reports (Richards, 11/3).

8 Nov 2010

Helical CT scanning reduces lung cancer deaths

In a major new study announced today by the National Cancer Institute, researchers including Brown University biostatistian Constantine Gatsonis and his colleagues found that screening for lung cancer using helical CT scanning reduced lung cancer deaths by 20 percent compared to using chest X-rays.

8 Nov 2010

Research Roundup: Basing insurance on results, not cost; Americans skeptical of public health efforts; seniors' comprehensive care

Copayment Reductions Generate Greater Medication Adherence In Targeted Patients. As health care costs have increased, some patients have sought to save money by cutting down on their medications.

8 Nov 2010

Americans sicker but live longer than the English: Study

According to a new study in the journal Demographics, and elderly American is not quite as healthy as his English counterpart, but does live just as long, if not longer. The study found that Americans aged 55 to 64 and 70 to 80 had higher rates of chronic diseases than same-aged English people, but they died at about the same rate. Americans aged 65 and older could be sicker than their English peers but lived longer.

5 Nov 2010

Rising kidney disease a worry – home dialysis may solve some problems

Kidney Health Australia (KHA) has released a report that predicts that the number of people needing treatment for serious kidney disease will triple to 30,000 by 2020 and treating serious kidney disease will cost the health system $12 billion over the next decade. The report, by the George Institute for Global Health, also found the annual cost of providing dialysis treatment was just over $79,000 per patient. This was compared to just over $49,000 per person taking part in a program which delivers the treatment not in a hospital but in the patient’s home.

5 Nov 2010

Mortality News and Research

Lung cancer in smokers versus non-smokers shows different genetic mutations

Study finds no association between working in wafer fabrication cleanrooms, cancer mortality

Hospitals need to work more to prevent heart attack deaths: Study

Conference of The MacLean Center for Clinical Medical Ethics to focus on health disparities

Regional workshop to discuss diarrheal disease solutions for Asia

Aromatase inhibitors increase side effects in women undergoing breast cancer therapy

Silence Therapeutics' Atu027 RNAi drug prevents pulmonary metastasis formation

Investigations examine Medicare’s dialysis system, CT scanners and drugs

Undergraduate students win Gates Foundation grant for low-cost ultrasound system

Long-term androgen deprivation therapy increases risk of fracture in older men with prostate cancer

Study demonstrates preventive effect of urate lowering therapy on cardiovascular mortality

Mobile technology improves diagnosis and treatment for mothers, newborns and children

Intercell aggregate revenues decrease 28.4% to EUR 21.1m in 9 months ended September 30, 2010

Statins do not reduce risk for colorectal cancer in postmenopausal women

New data on Soliris for PNH treatment to be presented at ASH Annual Meeting

Officials discuss HIV/AIDS in Caribbean during PANCAP meeting

Helical CT scanning reduces lung cancer deaths

Research Roundup: Basing insurance on results, not cost; Americans skeptical of public health efforts; seniors' comprehensive care

Americans sicker but live longer than the English: Study

Rising kidney disease a worry – home dialysis may solve some problems

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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