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DNA decoder – cheaper and faster

Life Technologies Corp. – a biotechnology company announced Tuesday that it has developed a machine to decode an individual's DNA in a day for just $1,000. The company said it was taking orders for the technology, which it expects to deliver in about a year. The Carlsbad, California, company said three major research institutions had already signed up for the $149,000 machine: the Baylor College of Medicine, the Yale School of Medicine and the Broad Institute of Cambridge, Massachusetts.

11 Jan 2012

Researchers analyze microorganisms in human gut as a complex, integrated biological system

For the first time, researchers have analyzed the multitude of microorganisms residing in the human gut as a complex, integrated biological system, rather than a set of separate species. Their approach has revealed patterns that correspond with excess body weight.

11 Jan 2012

UCSF, Sanofi enter $3.1 million collaboration to identify diabetes drug targets

The University of California, San Francisco has signed an alliance with international pharmaceutical company Sanofi to share expertise in diabetes research and identify drug targets that could lead to new therapies for both type 1 and type 2 diabetes.

11 Jan 2012

Damon Runyon Cancer Research Foundation names 18 new Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 18 new Damon Runyon Fellows at its fall Fellowship Award Committee review.

11 Jan 2012

Bladder cancer is one of the top 10 most common forms of cancer in the US

Bladder cancer, most frequently caused by smoking and exposure to carcinogens in the workplace, is one of the top 10 most common forms of cancer in men and women in the U.S. More than 70 percent of bladder cancers are diagnosed in stage T1 or less and have not invaded the muscle layer.

11 Jan 2012

Inherited breast and ovarian cancer drug trial re-launched in tablet form

Cancer Research UK's Drug Development Office has re-launched a trial of a promising drug to treat inherited breast and ovarian cancer - but this time taken as a tablet by outpatients.

11 Jan 2012

Disruption of circadian rhythms cause accelerated neurodegeneration and premature death

New research at Oregon State University provides evidence for the first time that disruption of circadian rhythms - the biological "clocks" found in many animals - can clearly cause accelerated neurodegeneration, loss of motor function and premature death.

11 Jan 2012

Scientists can now observe enhancer activity in real embryo

As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell's nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, can now see - and predict - exactly when each remote control is itself activated, in a real embryo.

10 Jan 2012

Females can manipulate sex of their offspring

Females influence the gender of their offspring so they inherit either their mother's or grandfather's qualities. 'High-quality' females - those which produce more offspring - are more likely to have daughters. Weaker females, whose own fathers were stronger and more successful, produce more sons.

10 Jan 2012

Personalized therapies may improve survival and QoL of patients with glioblastoma

Personalized prognostic tools and gene-based therapies may improve the survival and quality of life of patients suffering from glioblastoma, an aggressive and deadly form of brain cancer, reports a new University of Illinois study funded by the NIH National Cancer Institute.

10 Jan 2012

Life Technologies takes orders for new benchtop Ion Proton Sequencer

Life Technologies Corporation today announced it is taking orders for the new benchtop Ion Proton Sequencer that is designed to sequence the entire human genome in a day for $1,000.

10 Jan 2012

Sangamo BioSciences starts Phase 2 clinical studies to develop functional cure for HIV/AIDS

Sangamo BioSciences, Inc. announced today the initiation of two new Phase 2 clinical studies (SB-728-1101 and SB-728-902, Cohort 5) in its program to develop a "functional cure" for HIV/AIDS.

9 Jan 2012

TRON uses Ingenuity Variant Analysis to identify cancer driver variants

Ingenuity Systems, a leading provider of information and analysis solutions for life science researchers, today announced that TRON has used Ingenuity Variant Analysis to identify cancer driver variants that inform the development of an experimental individualized RNA-based therapeutic.

9 Jan 2012

Scientists identify key tumorigenic pathways in never-smoker lung adenocarcinoma patients

Researchers at the Translational Genomics Research Institute (TGen) have begun to identify mutations and cellular pathway changes that lead to lung cancer in never-smokers - a first step in developing potential therapeutic targets.

9 Jan 2012

Many parents share BRCA1/A2 test results with their children

A new study has found that when parents get tested for breast cancer genes, many of them share their results with their children, even with those who are very young. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed that most parents think that their children are not distressed when they learn about the test results.

9 Jan 2012

Scientists identify two genes involved in major symptoms of MeCP2 duplication disorder

The anxiety and behavioral issues associated with excess MeCP2 protein result from overexpression of two genes (Crh [corticotropin-releasing hormone] and Oprm 1 [mu-opioid receptor MOR 1]), which may point the way to treating these problems in patients with too much of the protein, said Baylor of Medicine scientists in a report that appears online in the journal Nature Genetics.

8 Jan 2012

Studies identify genes and small molecules against protein conformational diseases

Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic lateral sclerosis (ALS), cancer, cystic fibrosis and type 2 diabetes.

7 Jan 2012

Genes News and Research

DNA decoder – cheaper and faster

Researchers analyze microorganisms in human gut as a complex, integrated biological system

UCSF, Sanofi enter $3.1 million collaboration to identify diabetes drug targets

Damon Runyon Cancer Research Foundation names 18 new Fellows

Bladder cancer is one of the top 10 most common forms of cancer in the US

Inherited breast and ovarian cancer drug trial re-launched in tablet form

Disruption of circadian rhythms cause accelerated neurodegeneration and premature death

Scientists can now observe enhancer activity in real embryo

Females can manipulate sex of their offspring

Personalized therapies may improve survival and QoL of patients with glioblastoma

Life Technologies takes orders for new benchtop Ion Proton Sequencer

Sangamo BioSciences starts Phase 2 clinical studies to develop functional cure for HIV/AIDS

TRON uses Ingenuity Variant Analysis to identify cancer driver variants

Scientists identify key tumorigenic pathways in never-smoker lung adenocarcinoma patients

Many parents share BRCA1/A2 test results with their children

Scientists identify two genes involved in major symptoms of MeCP2 duplication disorder

Studies identify genes and small molecules against protein conformational diseases

Scientists map neurons that process different kinds of visual information

AHA honors Rice University professor with Established Investigator Award

Researchers produce chimeric monkeys with six distinct genomes

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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