Genes News and Research

RSS

Genetic evidence confirms role of group of virus-fighting genes in cancer development

Researchers have found a major piece of genetic evidence that confirms the role of a group of virus-fighting genes in cancer development.

15 Apr 2014

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed Wilms tumor, which regressed when Lin28 was withdrawn, indicating that strategies aimed at blocking or deactivating the gene hold therapeutic promise for children with Wilms.

15 Apr 2014

Three-gene test may aid earlier lung cancer detection

Methylation of three genes may help with the early diagnosis of non-small-cell lung cancer, research suggests.

14 Apr 2014

Two candidate mTOR therapy biomarkers identified in RCC

Two genes, TSC1 and MTOR, warrant further investigation as biomarkers for treatment benefit with rapalogs in patients with renal cell carcinoma, indicate study results published in Clinical Cancer Research.

14 Apr 2014

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

In 10% of human tumors there is a family history of hereditary disease associated with mutations in identified genes. The best examples are the cases of polyps in the large intestine associated with the APC gene and breast cancer associated with BRCA1 and BRCA2 genes.

11 Apr 2014

Researchers uncover new aspect of autism

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain.

11 Apr 2014

Viewpoints: Medicare's 'doctor payment problem'; a 'wasted advantage'; 'puzzling' Rand numbers

The news that a small percentage of the country's physicians collected billions of dollars from Medicare in a single year may or may not be a testament to individual greed; some of the top recipients are under investigation for allegedly bilking the system, while others work long hours delivering costly care.

11 Apr 2014

Researchers show development of new cell models that track, report clock gene function

The consequences of modern life -- shift work, cell phone addiction, and travel across time zones -- all disturb internal clocks. These are found in the brain where they regulate sleep and throughout the body where they regulate physiology and metabolism.

11 Apr 2014

Researchers develop novel assay to identify genes controlling pharynx regeneration in flatworms

As multicellular creatures go, planaria worms are hardly glamorous. To say they appear rudimentary is more like it. These tiny aquatic flatworms that troll ponds and standing water resemble brown tubes equipped with just the basics: a pair of beady light-sensing "eyespots" on their head and a feeding tube called the pharynx (which doubles as the excretory tract) that protrudes from a belly sac to suck up food.

11 Apr 2014

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that's tightly intertwined with DNA, a team led by scientists at The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014.

11 Apr 2014

Scientists solve a decades-long mystery of cell biology

A team led by scientists at The Scripps Research Institute has identified a long-sought protein that facilitates one of the most basic functions of cells: regulating their volume to keep from swelling excessively.

11 Apr 2014

Researchers untangle genetic and environmental factors related to drug reactions

Why do people respond differently to the same drug? For the first time, researchers have untangled genetic and environmental factors related to drug reactions, bringing us a step closer to predicting how a drug will affect us.

11 Apr 2014

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers reported at the American Association for Cancer Research Annual Meeting 2014.

10 Apr 2014

Researchers discover how of EBV virus takes over human cells gene regulating machinery

University of Montreal researchers have discovered how a component of the Epstein Barr (EBV) virus takes over our cells gene regulating machinery, allowing the virus to replicate itself.

10 Apr 2014

Stressful upbringings can leave imprints on genes of African American children

Stressful upbringings can leave imprints on the genes of children as young as age 9, according to a study led by Princeton University and Pennsylvania State University researchers. Such chronic stress during youth leads to physiological weathering similar to aging.

10 Apr 2014

Multiple genomic data could help improve studies of association between genes and disease

The difference between merely throwing around buzzwords like "personalized medicine" and "big data" and delivering on their medical promise is in the details of developing methods for analyzing and interpreting genomic data. In a pair of new papers, Brown University epidemiologist Yen-Tsung Huang and colleagues show how integrating different kinds of genomic data could improve studies of the association between genes and disease.

10 Apr 2014

Genes News and Research

Genetic evidence confirms role of group of virus-fighting genes in cancer development

Lin28 gene may hold clues to regeneration of damaged kidneys in adults

Three-gene test may aid earlier lung cancer detection

Two candidate mTOR therapy biomarkers identified in RCC

1/4 human tumor exist genetic polymorphisms linked with increased risk of cancer

Researchers uncover new aspect of autism

Viewpoints: Medicare's 'doctor payment problem'; a 'wasted advantage'; 'puzzling' Rand numbers

Researchers show development of new cell models that track, report clock gene function

Researchers develop novel assay to identify genes controlling pharynx regeneration in flatworms

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

Scientists solve a decades-long mystery of cell biology

Researchers untangle genetic and environmental factors related to drug reactions

Comprehensive genomic analysis of low-grade brain tumors sorts into three categories

Researchers discover how of EBV virus takes over human cells gene regulating machinery

Stressful upbringings can leave imprints on genes of African American children

Multiple genomic data could help improve studies of association between genes and disease

University of Montreal scientists discover molecular details of kissing disease virus attacks

Rice University research targets Parkinson's, Huntington's and other proteasomal diseases

Food experts to discuss pros and cons of GM crops at Food Integrity and Traceability Conference

Study: Honokiol reduces proliferation of renal cell carcinoma

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics