Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

OncoGenex provides update on Phase 2 Spruce trial in patients with untreated metastatic NSCLC

OncoGenex Pharmaceuticals, Inc. announced today that data from the Phase 2 Spruce trial evaluating the combination of apatorsen with carboplatin and pemetrexed in patients with untreated metastatic non-small cell lung cancer (NSCLC) did not reach the statistical significance required to demonstrate a progression-free survival (PFS) benefit.

20 Jan 2016

PD-L1 inhibition well-tolerated, active in metastatic RCC

The programmed death-ligand 1 inhibitor atezolizumab has a favourable toxicity profile and shows anti-tumour activity in previously treated patients with metastatic renal cell carcinoma, according to phase Ia trial findings.

19 Jan 2016

New USPSTF breast cancer screening recommendations may result in lethal consequences for women

If followed, new U.S. Preventive Services Task Force breast cancer screening recommendations will result in thousands of unnecessary deaths each year and thousands more women enduring extensive and expensive treatment than if their cancer had been found early by an annual mammogram.

12 Jan 2016

CTCA at Western announces launch of Phase II NivoPlus clinical trial

Cancer Treatment Centers of America at Western Regional Medical Center in Goodyear, Arizona, has announced the launch of Phase II of the NivoPlus clinical trial, which combines the immunotherapeutic agent nivolumab with chemotherapy drugs irinotecan and capecitabine.

11 Jan 2016

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

The conclusion drawn from a recent study that insertion of adeno-associated virus 2 (AAV2) into human DNA causes mutations leading to the development of hepatocellular carcinoma (HCC) was resoundingly rejected by leading researchers in the fields of gene therapy and molecular genetics.

7 Jan 2016

SillaJen reports initiation of multinational randomized Phase 3 study of Pexa-Vec in HCC patients

SillaJen, Inc., a private, clinical-stage, biotherapeutics company focused on the development of oncolytic immunotherapy products for cancer, has announced the initiation of a multinational randomized Phase 3 open-label study of its lead product candidate, Pexa-Vec (formerly JX-594), in patients with advanced liver cancer, also known as hepatocellular carcinoma (HCC).

5 Jan 2016

New study describes STING protein's role in potential suppression of colorectal cancer

A new study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine reports on a key finding about the immune system's response to tumor development following studies on colorectal cancer.

4 Jan 2016

HealthWell Foundation opens new fund to provide financial assistance to Medicare patients suffering from RCC

The HealthWell Foundation, an independent non-profit that provides a financial lifeline for inadequately insured Americans, today announced it has opened a new fund to provide financial assistance to Medicare patients suffering from renal cell carcinoma (RCC).

31 Dec 2015

Genetic modification in esophagus can lead to esophageal cancer

A genetic modification in the mucous membrane of the esophagus, the Barrett esophagus, can lead to esophageal cancer. If certain biomarkers are contained in these tissue alterations, so-called miDNA, these are extremely short DNA strands, it could be an indication that this preliminary stage of esophageal cancer indeed leads to cancer.

28 Dec 2015

Four unrelated families share identical BAP1 mutation that causes several cancers

University of Hawai'i Cancer Center researchers discovered members of four families, apparently unrelated and living in different states across the US, shared the identical mutation of a gene called BAP1 that causes mesothelioma, melanoma, renal carcinoma and other cancers.

23 Dec 2015

Novel strategies on the way for difficult-to-treat head and neck cancer

Novel strategies are on the way for difficult-to-treat and advanced head and neck cancer, the most heterogeneous group of malignancies which are generally associated with poor survival, and encouraging results have been presented at the first ESMO Asia 2015 Congress in Singapore.

17 Dec 2015

Active surveillance may be a viable treatment for select DCIS patients

Active surveillance could be a viable alternative to surgery and radiation for select patients with ductal carcinoma in situ, or DCIS, according to a mathematical model developed by researchers at Duke University.

17 Dec 2015

Discovery could pave way for targeted therapies to treat penile cancer

Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.

15 Dec 2015

Anastrozole drug effective in treating early form of breast cancer

The drug anastrozole is effective in treating an early form of breast cancer, according to a clinical trial led by Queen Mary University of London. The results of the IBIS-II DCIS trial show that anastrozole is as effective as tamoxifen for this type of breast cancer and could offer a new treatment option for post-menopausal women.

12 Dec 2015

New way of growing fallopian tube cells in culture may boost understanding of female genital diseases

A new way of growing fallopian tube cells in culture is expected to give a boost to our understanding and prevention of female gynecological diseases, such as infertility, inflammatory disease, and ovarian cancer.

12 Dec 2015

OncoSec reports net loss of $7.0 million for first quarter of fiscal 2016

OncoSec Medical Incorporated, a company developing DNA-based intratumoral cancer immunotherapies, today announced financial results for the first quarter of fiscal year ended July 31, 2016.

8 Dec 2015

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Scientists have shown for the first time why loss of the enzyme CD73 in human cancer promotes tumor progression.

8 Dec 2015

Researchers discover 'triple attack' technique to target liver cancer tumors

In an interdisciplinary collaboration between prominent academic and industry investigators, researchers have discovered a novel method for repositioning an FDA-approved anti-cancer compound so it can specifically target liver cancer tumors. A 'triple attack' technique combining chemotherapy, thermal ablation, and hyperthermia provided a highly targeted, yet minimally invasive approach.

8 Dec 2015

Age and body fat also contribute to breast cancer risk, say Johns Hopkins researchers

Although several studies suggest that women with denser breast tissue have an increased risk of breast cancer, a new study by Johns Hopkins researchers discredits breast density as a risk factor in and of itself, instead concluding that age and body fat, especially in the upper belly, contribute to the breast cancer seen in many patients.

7 Dec 2015

HBsAg may persist in chronic HBV patients beyond seroclearance

The use of a highly sensitive assay for the detection of hepatitis B surface antigen suggests that HBsAg negativity as evaluated by the conventional test may not be indicative of seroclearance in patients with chronic hepatitis B virus infection.

3 Dec 2015

Carcinoma News and Research

Further Reading

OncoGenex provides update on Phase 2 Spruce trial in patients with untreated metastatic NSCLC

PD-L1 inhibition well-tolerated, active in metastatic RCC

New USPSTF breast cancer screening recommendations may result in lethal consequences for women

CTCA at Western announces launch of Phase II NivoPlus clinical trial

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

SillaJen reports initiation of multinational randomized Phase 3 study of Pexa-Vec in HCC patients

New study describes STING protein's role in potential suppression of colorectal cancer

HealthWell Foundation opens new fund to provide financial assistance to Medicare patients suffering from RCC

Genetic modification in esophagus can lead to esophageal cancer

Four unrelated families share identical BAP1 mutation that causes several cancers

Novel strategies on the way for difficult-to-treat head and neck cancer

Active surveillance may be a viable treatment for select DCIS patients

Discovery could pave way for targeted therapies to treat penile cancer

Anastrozole drug effective in treating early form of breast cancer

New way of growing fallopian tube cells in culture may boost understanding of female genital diseases

OncoSec reports net loss of $7.0 million for first quarter of fiscal 2016

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Researchers discover 'triple attack' technique to target liver cancer tumors

Age and body fat also contribute to breast cancer risk, say Johns Hopkins researchers

HBsAg may persist in chronic HBV patients beyond seroclearance

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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