Chimeric Antigen Receptor News and Research

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Protein's location in a cell affects impact on disease

If the fight against breast cancer were a criminal investigation, then the proteins survivin, HDAC6, CBP, and CRM1 would be among the shadier figures. In that vein, a study to be published in the March 30 Journal of Biological Chemistry is the police report that reveals a key moment for keeping cancer cells alive: survivin's jailbreak from the nucleus, aided and abetted by the other proteins.

29 Mar 2012

Inhibitory control test and lactulose for MHE saves more than $3 million over 5 years

A late stage liver condition, known as minimal hepatic encephalopathy (MHE), is associated with impaired driving skills and greater risk of motor vehicle accidents. Cost analysis of management strategies for detection and treatment of MHE are published in the April issue of Hepatology, a journal of the American Association for the Study of Liver Diseases.

29 Mar 2012

Stress response reduces memory during tests in older adults

Your mother had a doctor's appointment for a memory test. The results are conclusive: she presents with the first signs of Alzheimer type dementia. Now, to get to her appointment, your mother, who is no longer used to driving in town, took her car, looked for a parking space for 15 minutes, got lost in a labyrinth of one-way streets, had never used those new electronic parking meters before and is convinced that the "machine" stole her credit card number.

28 Mar 2012

On Capitol Hill, both parties see political advantage in Rep. Ryan's newest plan

The budget proposal offered last week by the Wisconsin Republican would revamp the Medicare system.

27 Mar 2012

1 in 5 Australians have taken an expired medicine

NPS is urging all Australians to clean out their medicine cabinets today as part of national Be Medicinewise Week 2012. New research from NPS found around 1 in 5 people reported ever having taken an expired medicine.

26 Mar 2012

Synthetic pasta-like objects are major chemistry advances for regenerative medicine

Medicine's recipe for keeping older people active and functioning in their homes and workplaces - and healing younger people injured in catastrophic accidents - may include "noodle gels" and other lab-made invisible filaments that resemble uncooked spaghetti with nanoscale dimensions, a scientist said here today at the 243rd National Meeting & Exposition of the American Chemical Society (ACS).

26 Mar 2012

Simple and accurate test for peanut allergy

The Murdoch Children’s Research Institute and University of Melbourne researchers discovered a two-pronged blood test will confirm peanut allergies instead of putting children through risky oral food challenge tests.

21 Mar 2012

State roundup: Ariz. long-term care plan advances; N.H. moves to repeal 'certificate-of-need'; Minn. ALEC legislation

The Senate Appropriations Committee unanimously passed a bill Tuesday that would make long-term health care more affordable for middle-class families. Rep. Steve Farley, D-Tucson, sponsored House Bill 2713, which would allow Arizonans to set aside money in a tax-deductible savings account to pay for long-term health-care expenses. It would also create tax deductions for long-term health insurance premiums.

16 Mar 2012

Allergy-free egg in the making

Researchers at CSIRO and experts at Geelong's Deakin University have found a way to “switch off” four egg allergens. These modified eggs could produce chickens that lay hypoallergenic eggs but the genes and DNA of the chicken would remain unaltered.

15 Mar 2012

New research to precisely identify the 'dilemma zone' at traffic stoplights

Hundreds of lives are being lost each year in the United States because of mistakes made in what engineers call the "dilemma zone" - that area before a stoplight intersection where the traffic light turns yellow and the driver isn't sure whether to stop or go ahead.

15 Mar 2012

Surgical intervention can be life-restoring for people with intractable temporal lobe epilepsy

While the thought of any type of surgery can be disconcerting, the thought of brain surgery can be downright frightening. But for people with a particular form of epilepsy, surgical intervention can literally be life-restoring.

8 Mar 2012

Concussion in kids may lead to memory and cognitive problems at school later in life

The researchers from Nationwide Children’s Hospital and The Ohio State University looked at 186 children aged 8 to 15 who experienced concussion - most commonly in a fall or while playing sports - or other brain injury from a car accident or other causes. The children’s parents were asked to fill out a standard questionnaire to assess their child’s cognitive and physical status before the concussion, and again two weeks, three months and a year later. These responses were compared to those from parents of 99 similar children who came into the emergency room with orthopedic injuries.

7 Mar 2012

HGVs pose increased risk of death and serious injury to cyclists

A study by researchers at Queen Mary, University of London and Barts and The London NHS Trust proves that HGVs pose the greatest risk of death and serious injury to cyclists.

6 Mar 2012

Penn-led team develops universal approach to personalized cancer therapy based on T cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania report this month in Cancer Research a universal approach to personalized cancer therapy based on T cells. It is the first time a system for making an adaptable, engineered T-cell to attack specific tumor types has been proposed, depending on which abnormal proteins, called antigens, are expressed by individual patients' tumor cells.

6 Mar 2012

Sleep specialists offer advice on why Daylight Saving Time can be hazardous to health

It's National Sleep Awareness Week, and Loyola University Health System sleep specialists are offering advice on -- Why Daylight Saving Time, which begins Sunday, March 11, can be hazardous to your health.

6 Mar 2012

Brain more flexible and trainable than previously thought

Opening the door to the development of thought-controlled prosthetic devices to help people with spinal cord injuries, amputations and other impairments, neuroscientists at the University of California, Berkeley, and the Champalimaud Center for the Unknown in Portugal have demonstrated that the brain is more flexible and trainable than previously thought.

4 Mar 2012

First poll to ask transportation professionals about sleep habits and work performance

The people we trust to take us or our loved ones from place to place struggle with sleep, according to the National Sleep Foundation's (NSF) 2012 Sleep in America poll. It is the first poll to ask transportation professionals, including pilots, train operators, truck, bus, taxi and limo drivers about their sleep habits and work performance.

4 Mar 2012

IPS examines gender discrimination, disparity in child mortality in India

Inter Press Service examines gender discrimination and mortality in India, writing, "Global infant and child mortality rates have been on the decline in recent years, with a large portion of the world seeing young girls experiencing higher rates of survival than young boys; but India remains the exception to this positive trend."

3 Mar 2012

Early surgical intervention stops seizures and improves quality of life

3 Mar 2012

Polymer-based medical implants can produce harmful free radicals

A polymer is a mesh of chains, which slowly break over time due to the pressure from ordinary wear and tear. When a polymer is squeezed, the pressure breaks chemical bonds and produces free radicals: ions with unpaired electrons, full of untapped energy. These molecules are responsible for aging, DNA damage and cancer in the human body.

3 Mar 2012

Chimeric Antigen Receptor News and Research

Protein's location in a cell affects impact on disease

Inhibitory control test and lactulose for MHE saves more than $3 million over 5 years

Stress response reduces memory during tests in older adults

On Capitol Hill, both parties see political advantage in Rep. Ryan's newest plan

1 in 5 Australians have taken an expired medicine

Synthetic pasta-like objects are major chemistry advances for regenerative medicine

Simple and accurate test for peanut allergy

State roundup: Ariz. long-term care plan advances; N.H. moves to repeal 'certificate-of-need'; Minn. ALEC legislation

Allergy-free egg in the making

New research to precisely identify the 'dilemma zone' at traffic stoplights

Surgical intervention can be life-restoring for people with intractable temporal lobe epilepsy

Concussion in kids may lead to memory and cognitive problems at school later in life

HGVs pose increased risk of death and serious injury to cyclists

Penn-led team develops universal approach to personalized cancer therapy based on T cells

Sleep specialists offer advice on why Daylight Saving Time can be hazardous to health

Brain more flexible and trainable than previously thought

First poll to ask transportation professionals about sleep habits and work performance

IPS examines gender discrimination, disparity in child mortality in India

Early surgical intervention stops seizures and improves quality of life

Polymer-based medical implants can produce harmful free radicals

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