Genes News and Research

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Gene-therapy trial to restore hearing in deaf mice

Researchers have found long-sought genes in the sensory hair cells of the inner ear that, when mutated, prevent sound waves from being converted to electric signals - a fundamental first step in hearing. The team, co-led by Jeffrey Holt, PhD, in the department of otolaryngology at Children-s Hospital Boston, and Andrew Griffith, MD, PhD, of the NIH-s National Institute on Deafness and other Communication Disorders (NIDCD), then restored these electrical signals in the sensory cells of deaf mice by introducing normal genes.

22 Nov 2011

Scientists search for main culprit behind Sj-gren's syndrome

Researchers want to find the main culprit behind the dry, irritated eyes, mouth, throat, skin, nose and more afflicting 1-3 percent of the population.

22 Nov 2011

Targeting synthetic RNA to specific gene could help reduce severity of SMA

A team of University of Missouri researchers have found that targeting a synthetic molecule to a specific gene could help the severity of the disease Spinal Muscular Atrophy (SMA) - the leading genetic cause of infantile death in the world.

22 Nov 2011

Scientists discover second faulty gene linked to ALS

Following a major Northwestern Medicine breakthrough that identified a common converging point for all forms of amyotrophic lateral sclerosis (ALS and Lou Gehrig's disease), a new finding from the same scientists further broadens the understanding of why cells in the brain and spinal cord degenerate in the fatal disease.

21 Nov 2011

WaferGen third quarter revenue decreases to $89,000

WaferGen Biosystems, Inc., an emerging genomic analysis company, today reported financial results for the three and nine months ended September 30, 2011 and announced a revised plan to commercialize and increase adoption of its SmartChip System.

21 Nov 2011

MedUni Vienna researchers discover important regulators in development of stem cells

A team of researchers at the MedUni Vienna's Institute of Medical Genetics has discovered that two genes (TSC/Tuberin and PRAS40) are extremely important regulators in the development of stem cells: if these genes are switched off, the stem cells do not develop but instead die a programmed cell death.

21 Nov 2011

New method for counting molecules

Researchers at the Swedish medical university Karolinska Institutet have developed a new method for counting molecules.

21 Nov 2011

Two genetic rearrangements may trigger 5 to 7% of breast cancers

Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers.

20 Nov 2011

Researchers discover more about function of muscle stem cells

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

20 Nov 2011

UVA develops new and faster method to track superbugs

University of Virginia Health System researchers are the first in the world to develop a new and faster method to track major infection-causing "superbugs" - a major key in preventing the spread of deadly infections.

19 Nov 2011

Cancer Research UK embarks on new initiative to unravel genetic secrets behind cancers

Unravelling the genetic secrets behind a range of cancers - from understanding how certain genes control cancer to determining how the disease evades treatment - is the aim of a new initiative from Cancer Research UK.

18 Nov 2011

Simple roundworm may serve as ideal skin wound healing lab model

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's response to healing skin wounds, a serious problem in diabetics and the elderly.

18 Nov 2011

NYU Langone cardiovascular experts present new research findings at AHA 2011

Experts from the Cardiac & Vascular Institute at NYU Langone Medical Center presented new research findings at the American Heart Association Scientific Sessions 2011 held November 12-16, 2011 in Orlando, Florida.

18 Nov 2011

Study demonstrates how DISC1 variants affect brain development

Significant progress has been made in understanding the genetic risk factors underlying psychiatric disease. Recent studies have identified common genetic mutations conferring modest risk and rare variants comprising significant risk. One example of a rare cause of psychiatric disorders is the Disrupted in Schizophrenia-1 (DISC1) gene, first identified in a large Scottish pedigree displaying schizophrenia, bipolar disorder and depression.

18 Nov 2011

Researchers use baker's yeast to gain insight into chromosome separation process

Researchers at the Stowers Institute for Medical Research used, ironically enough, the single-celled organism Saccharomyces cerevisiae -- commonly known as baker's yeast -- to gain new insight into the process by which chromosomes are physically segregated during cell division.

18 Nov 2011

Stroke incidence related to blood type: Study

A latest study reveals that the risk for stroke maybe tied to blood type, with men and women with type AB and women with type B facing greater risk than people with type O. Researchers add that this study does not prove the link but it agrees with other studies that have tied A, B, and AB to heart attack and to blood clots in the legs. And type O has been linked to a heightened risk for bleeding, which implies less chance of the clots that are responsible for most strokes.

17 Nov 2011

Are genes and hormones determinants of empathy and sensitivity in human nature?

According to latest research a first look or observation for just about 20 seconds maybe all that is needed to know if a person is nurturing and socially sensitive. These people may be genetically wired to be so say researchers.

17 Nov 2011

Hard-core smokers most strongly influenced by genetic factors

A new study of twins led by the University of Colorado Boulder shows that today's smokers are more strongly influenced by genetic factors than in the past and that the influence makes it more difficult for them to quit.

17 Nov 2011

Genetic basis of human cortical regionalization similar to patterns found in other mammals, MRI study affirms

A new study using magnetic resonance imaging data of 406 adult human twins affirms the long-standing idea that the genetic basis of human cortical regionalization - the organization of the outer brain into specific functional areas - is similar to and consistent with patterns found in other mammals, indicating a common conservation mechanism in evolution.

17 Nov 2011

Modified spider silk proteins for cancer gene therapy

A new episode in the American Chemical Society's (ACS) award-winning "Global Challenges/Chemistry Solutions" podcast series spins a real-life tale in which spider silk shows promise for overcoming a major barrier to the use of gene therapy in everyday medicine.

17 Nov 2011