Genes News and Research

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Archaeologists find oldest complete example of metastatic cancer in 3,000 year-old skeleton

Archaeologists have found the oldest complete example in the world of a human with metastatic cancer in a 3,000 year-old skeleton.

19 Mar 2014

Nine fellows selected to receive Dennis Weatherstone Predoctoral Fellowship for next two years

Autism Speaks, the world's leading autism science and advocacy organization, today announced the sixth class of The Dennis Weatherstone Predoctoral Fellows funded by the Stavros Niarchos Foundation.

19 Mar 2014

Body clock's could be utilized to improve current therapies to delay onset of chronic lung diseases

The body clock's natural rhythm could be utilized to improve current therapies to delay the onset of chronic lung diseases.

From The University of Manchester 18 Mar 2014

Researchers create new line of human embryonic stem cells

Researchers at the University of Washington have successfully created a line of human embryonic stem cells that have the ability to develop into a far broader range of tissues than most existing cell lines.

18 Mar 2014

Researchers examine how diabetes drug can benefit cancer patients

For several years, a class of anti-diabetic drugs known as biguanides, has been associated with anti-cancer properties. A number of retrospective studies have shown that the widely used diabetes drug metformin can benefit some cancer patients.

18 Mar 2014

Sequencing reveals genetic diversity in hospital-acquired bacterium

Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

18 Mar 2014

Vitamin D receptor gene variant protects against male LUTS

An international research effort aimed at identifying the genetic basis of lower urinary tract symptoms has identified five candidate genes, one of which – encoding the vitamin D receptor – is consistently protective against these symptoms in men.

17 Mar 2014

S. pneumoniae thrives in human saliva

Streptococcus pneumoniae is able to survive and thrive in human saliva, Dutch researchers have shown.

17 Mar 2014

TAF proteins may serve as potential targets to fight ovarian cancer

In the complex genomic and molecular conspiracy that gives rise to ovarian cancer, what if researchers have been missing a whole set of suspects because they've been hiding in plain sight?

17 Mar 2014

Findings reveal potential drug targets for small cell lung cancer

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as "drivers," help spur cells to grow out of control, while others ("passengers") are merely along for the ride.

17 Mar 2014

Findings reveal that miR-34 genes are bona fide tumor suppressors

Cornell University researchers report they have discovered direct genetic evidence that a family of genes, called MicroRNA-34 (miR-34), are bona fide tumor suppressors.

17 Mar 2014

Edison Pharmaceuticals begins EPI-743 clinical trial in children with Pearson syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2 study entitled "A Phase 2 Safety and Efficacy Study of EPI-743 (Vincerinone™) in Children with Pearson Syndrome." The Investigative New Drug application (IND) was approved by the Food and Drug Administration, Office of Hematology and Oncology Products.

17 Mar 2014

Researchers identify novel protein that explains how biological clocks regulate human sleep

In a series of experiments sparked by fruit flies that couldn't sleep, Johns Hopkins researchers say they have identified a mutant gene - dubbed "Wide Awake" - that sabotages how the biological clock sets the timing for sleep.

17 Mar 2014

Researchers discover USP9X gene that sheds new light on mysteries of brain development, disability

Research from the University of Adelaide has confirmed that a gene linked to intellectual disability is critical to the earliest stages of the development of human brains.

17 Mar 2014

Researchers identify two novel genes associated with development of rare, aggressive blood cancer

Researchers have identified two novel cancer genes that are associated with the development of a rare, highly aggressive, cancer of blood vessels. These genes may now act as markers for future treatments and explain why narrowly targeted therapies that are directed at just one target fail.

17 Mar 2014

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks -- a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

17 Mar 2014

Racial differences in health outcomes between blacks and whites associated with synthesize of Vitamin D

A new study investigating racial disparities in birth outcomes shows that contrary to some theories Vitamin D is unlikely to play a role in differences in preterm birth and low birth weight between African-Americans and whites.

14 Mar 2014

Researchers use computer-aided design tool to create genetic languages of biological systems

Researchers at Virginia Tech and the Massachusetts Institute of Technology have used a computer-aided design tool to create genetic languages to guide the design of biological systems.

14 Mar 2014

CNIO scientist wins 2014 Stewart Rahr-PCF Young Investigator Award from Prostate Cancer Foundation

David Olmos, the Spanish National Cancer Research Centre's Head of the Prostate Cancer and Genitourinary Tumours Clinical Research Unit, has won the 2014 Stewart Rahr-PCF Young Investigator Award, endowed by the Prostate Cancer Foundation - the leading philanthropic organisation for cutting-edge research into prostate cancer.

14 Mar 2014

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.

13 Mar 2014

Genes News and Research

Archaeologists find oldest complete example of metastatic cancer in 3,000 year-old skeleton

Nine fellows selected to receive Dennis Weatherstone Predoctoral Fellowship for next two years

Body clock's could be utilized to improve current therapies to delay onset of chronic lung diseases

Researchers create new line of human embryonic stem cells

Researchers examine how diabetes drug can benefit cancer patients

Sequencing reveals genetic diversity in hospital-acquired bacterium

Vitamin D receptor gene variant protects against male LUTS

S. pneumoniae thrives in human saliva

TAF proteins may serve as potential targets to fight ovarian cancer

Findings reveal potential drug targets for small cell lung cancer

Findings reveal that miR-34 genes are bona fide tumor suppressors

Edison Pharmaceuticals begins EPI-743 clinical trial in children with Pearson syndrome

Researchers identify novel protein that explains how biological clocks regulate human sleep

Researchers discover USP9X gene that sheds new light on mysteries of brain development, disability

Researchers identify two novel genes associated with development of rare, aggressive blood cancer

Scientists discover gene variation that makes humans have healthier blood lipid levels, reduced risk of heart attacks

Racial differences in health outcomes between blacks and whites associated with synthesize of Vitamin D

Researchers use computer-aided design tool to create genetic languages of biological systems

CNIO scientist wins 2014 Stewart Rahr-PCF Young Investigator Award from Prostate Cancer Foundation

Patient with advanced bladder cancer shows complete response to everolimus and pazopanib drugs

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