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Retinal scans may provide an early sign of Alzheimer's disease

While it has been said that the eyes are a window to the soul, a new study shows they could be a means for understanding diseases of the brain.

17 May 2021

Older heart failure patients significantly benefit from tailored cardiac rehab program

Older patients hospitalized with acute heart failure who participated in a novel 12-week physical rehabilitation (rehab) program tailored to address their specific physical impairments had significant gains not only in physical functioning but also quality of life and depression compared with those receiving usual care, regardless of their heart's ejection fraction, according to a new study presented at the American College of Cardiology's 70th Annual Scientific Session.

17 May 2021

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin-converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks.

17 May 2021

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

Preliminary clinical trial results from an ongoing Phase 2/3 trial led by Laurent M. Humeau of Inovio Pharmaceuticals suggest the two-dose INO-4800 vaccine is safe for use in adults of varying ages. The results expand on phase 1 trial results that found the vaccine was safe and tolerable in 38 participants.

16 May 2021

Groundbreaking study optimizes patient's own immune system to fight tumors

A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient's own immune system to fight tumors.

14 May 2021

Oral TXA is equally efficacious at preventing blood loss in orthopedic surgery, interim study suggests

Interim results of a study conducted by researchers at Hospital for Special Surgery (HSS) suggest that oral tranexamic acid (TXA) is non-inferior to intravenous (IV) TXA in preventing blood loss in total knee and total hip replacement surgery.

14 May 2021

Unique pre-clinical model enables study of HIV infection and testing of new therapies

A team led by researchers at Weill Cornell Medicine and Children's National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease.

14 May 2021

A look at how coronavirus disease (COVID-19) affects Parkinson's

Earlier, herpes simplex virus (HSV), influenza virus A, measles virus, cytomegalovirus (CMV), and mumps virus have all been associated with after-effects of the virus that includes Parkinson's disease (PD). This list may now include SARS-CoV-2.

14 May 2021

NK cells combined with bispecific antibody display potent anti-tumor activity against lymphoma cells

Cytokine-activated natural killer (NK) cells derived from donated umbilical cord blood, combined with an investigational bispecific antibody targeting CD16a and CD30 known as AFM13, displayed potent anti-tumor activity against CD30+ lymphoma cells, according to a new preclinical study from researchers at The University of Texas MD Anderson Cancer Center.

13 May 2021

No placental damage observed in case study of pregnant women with mRNA COVID-19 vaccinations

New research by a team at Northwestern University Feinberg School of Medicine, USA, suggests that the COVID-19 vaccine does not damage the placenta and may be safe to use during pregnancy.

13 May 2021

Black fungus complicates India's COVID pandemic

India faces a global health crisis as the number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections reaches over 23.7 million. As India's health system buckles with increased admissions and a lack of resources, another health threat has emerged.

13 May 2021

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

Researchers in the UK have presented a multi-omics integrated blood atlas that delineates the host immune response in patients with coronavirus disease 2019 (COVID-19) of varying severity, providing a unique reference resource for the interpretation of datasets generated from interventional trials.

13 May 2021

International experts are working to provide evidence-based guidelines for radiation therapy dosing for children

Annually, more than 350,000 children in the world are affected by pediatric cancer. Radiation has improved outcomes dramatically, but the damage caused to healthy tissue can affect the long-term health of a child.

13 May 2021

New, non-invasive method measures brain blood flow with light

A new, noninvasive method for measuring brain blood flow with light has been developed by biomedical engineers and neurologists at the University of California, Davis, and used to detect brain activation.

13 May 2021

Girls more likely to develop metabolic alterations associated with obesity than boys

A study of 92 adolescents conducted in Brazil suggests girls are more likely than boys to develop metabolic alterations associated with obesity, such as high blood pressure and excessive blood levels of cholesterol and triglycerides (dyslipidemia).

12 May 2021

New peptide could allow cannabis to fight pain without side effects

Many people live with chronic pain, and in some cases, cannabis can provide relief. But the drug also can significantly impact memory and other cognitive functions.

12 May 2021

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.

12 May 2021

Scientists identify molecular mechanism behind weight gain in patients taking antipsychotics

Scientists with UT Southwestern's Peter O'Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication.

12 May 2021

Simple sugar could play a key role in the development of progressive MS

Multiple sclerosis, or MS for short, manifests itself slightly differently in each person - which is why some call it "the disease of a thousand faces."

12 May 2021

Study reveals genes that cause loss of lung function in active smokers

Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing. It is the third leading cause of death worldwide. Current treatments for COPD only affect symptoms, not progression. Identifying who is going to get COPD before they get it is key to figuring out how to intercept the disease at an early stage.

12 May 2021

Blood News and Research

Retinal scans may provide an early sign of Alzheimer's disease

Older heart failure patients significantly benefit from tailored cardiac rehab program

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

Phase 2 trial shows INO-4800 SARS-CoV-2 DNA vaccine safe and tolerable in adults

Groundbreaking study optimizes patient's own immune system to fight tumors

Oral TXA is equally efficacious at preventing blood loss in orthopedic surgery, interim study suggests

Unique pre-clinical model enables study of HIV infection and testing of new therapies

A look at how coronavirus disease (COVID-19) affects Parkinson's

NK cells combined with bispecific antibody display potent anti-tumor activity against lymphoma cells

No placental damage observed in case study of pregnant women with mRNA COVID-19 vaccinations

Black fungus complicates India's COVID pandemic

Comprehensive blood atlas of COVID-19 identifies hallmarks of disease severity

International experts are working to provide evidence-based guidelines for radiation therapy dosing for children

New, non-invasive method measures brain blood flow with light

Girls more likely to develop metabolic alterations associated with obesity than boys

New peptide could allow cannabis to fight pain without side effects

New drug-like compound could effectively block a critical step in malaria parasite life cycle

Scientists identify molecular mechanism behind weight gain in patients taking antipsychotics

Simple sugar could play a key role in the development of progressive MS

Study reveals genes that cause loss of lung function in active smokers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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