Research News and Research

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Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

Takeda Pharmaceutical Company Limited, a global pharmaceutical company, and Envoy Therapeutics Inc., a recently formed drug discovery company, today announced that they have formed a three-year research alliance aimed at discovering drugs for schizophrenia that will have greater efficacy and safety compared to current therapies.

11 Oct 2010

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

A drug being developed as a treatment for ovarian cancer has shown single agent activity with durable disease control in some patients in a Phase-II clinical trial, an international research group has reported.

11 Oct 2010

Flu season looking 'typical,' CDC says

Flu activity in the Southern Hemisphere, where the flu season is ending, has been 'typical,' the federal Centers for Disease Control and Prevention said Thursday. All three types of flu that normally circulate are present, although the H1N1 'swine flu' strain that caused last year's pandemic has replaced the seasonal H1N1 strain that circulated before 2009.

11 Oct 2010

Study finds inconsistencies in methods to identify CA-BSI infection in pediatric patients

A new study looking at how hospitals identify pediatric patients who develop catheter-associated bloodstream infections (CA-BSI) found significant inconsistencies in the methods used to report the number of patients who develop them.

11 Oct 2010

Obesity can accelerate progression of acute lymphoblastic leukemia: Study

The first study to demonstrate that obesity can directly accelerate the progression of acute lymphoblastic leukemia (ALL) has been conducted at The Saban Research Institute of Childrens Hospital Los Angeles and was published in Cancer Prevention Research, on October 5, 2010.

11 Oct 2010

Smoking leads to epigenetic changes associated with cancer development: Research

For the first time, UK scientists have reported direct evidence that taking up smoking results in epigenetic changes associated with the development of cancer.The results were reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.

11 Oct 2010

Researchers find new surface adaptation mechanism of biofilm-forming pathogen

Many drug-resistant infections are the result of bacterial biofilms, structured aggregates of bacteria that live on surfaces and that are extremely resistant to environmental stresses. These biofilms impact human health in many ways - cystic fibrosis, for example, is a disease in which patients die from airway bacterial biofilm infections that are invulnerable to even the most potent antibiotics.

11 Oct 2010

Researchers determine genetic structures of bacteria that cause Lyme disease

Researchers Dr. Steven E. Schutzer of UMDNJ-New Jersey Medical School and Dr. Claire M. Fraser-Liggett of the Institute for Genome Sciences, University of Maryland, and their collaborators have made a major achievement toward better understanding Lyme disease, by determining the complete genetic structures of 13 strains of the bacteria that cause the disease.

11 Oct 2010

Researchers create experimental vaccine for Alzheimer's disease

Researchers at UT Southwestern Medical Center have created an experimental vaccine against beta-amyloid, the small protein that forms plaques in the brain and is believed to contribute to the development of Alzheimer's disease.

11 Oct 2010

IPS examines water, sanitation MDG Targets

Inter Press Service looks at the U.N. Human Rights Council's (HRC) endorsement of water and sanitation as a basic human right last week, and the reality that water and sanitation have remained two of the most neglected sub-texts of the eight Millennium Development Goals (MDGs) which came under scrutiny at the MDG summit in September.

11 Oct 2010

Scientists identify molecular mechanism of muscle stem cell differentiation

Under normal circumstances, adult stem cells reside in muscle tissue, where they can differentiate into a number of different cell types. After an injury (or even a tough workout), muscles are inflamed as cells and molecules flood the area to control damage and begin repairs. When called upon to replace muscle tissue damaged by injury or genetic disease, some muscle stem cells differentiate, becoming new muscle cells, while others make more stem cells. At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team of scientists led by Pier Lorenzo Puri, M.D., Ph.D., recently uncovered the molecular messengers that translate inflammatory signals into the genetic changes that tell muscle stem cells to differentiate.

11 Oct 2010

Aetna, other insurers develop plans to help cut costs

Health insurer Aetna Inc. is developing plans to pay a major San Diego medical group enhanced fees for providing extra services to keep patients healthier, and to share any resulting cost savings.

11 Oct 2010

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Infinity Pharmaceuticals, Inc. today announced promising preliminary results from a Phase 1 study of IPI-926, its novel, oral small molecule that targets the Hedgehog pathway.

11 Oct 2010

Administration's waivers of health law raise questions about 'mini-med' plans

The White House on Thursday defended granting waivers to some employers from a key provision of the new health care law, saying it was the best way to keep people insured until the law fully takes effect.

11 Oct 2010

IntegenX receives DTRA contract to develop ISS system for rapid detection of emerging pathogens

IntegenX, Inc. today announced that it has been awarded a new contract by the Defense Threat Reduction Agency (DTRA) of the U.S. Department of Defense (DoD) to develop an Integrated Sample-to-Sequence (ISS) system for rapid detection and identification of genetically engineered bacteria and viruses, medically relevant bacteria and viruses, and emerging pathogens.

11 Oct 2010

Research may offer new therapy targets for drug-resistant breast tumors

Researchers at the University of Illinois at Chicago College of Medicine have found how gene expression that may contribute to drug resistance is ramped up in unusual types of breast tumors. Their findings may offer new therapy targets.

11 Oct 2010

Are 'mini-med' plan waivers a good idea?

Kaiser Health News staff writer Andrew Villegas asks two experts with differing views whether it was a good idea for the Obama administration to grant one-year waivers to about 30 insurers, employers and union health plans to continue offering what are dubbed "mini-med" insurance plans.

11 Oct 2010

Anti-HER2 antibody-drug conjugate effective as first-line therapy for advanced breast cancer: Research

A new type of breast cancer treatment has shown encouraging activity as a first-line therapy in HER2-positive metastatic disease, researchers reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.

11 Oct 2010

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

BioTime, Inc., Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced today that Cell Cure and Teva Pharmaceutical Industries Ltd. have entered into an exclusive license option agreement to develop and commercialize Cell Cure's OpRegen product for the treatment of age-related macular degeneration (AMD).

11 Oct 2010

Opinions: Learning to live with malaria; U.S. food aid policy; foreign aid reform

Recent discoveries of a possible wild reservoir for humankind's most malignant malaria, some 130 years after the discovery of the malaria parasite, could mean that it will be impossible to eradicate malaria,Sonia Shah, the author of The Fever, How Malaria Has Ruled Humankind for 500,000 Years,observes in an International Herald Tribune opinion piece.

11 Oct 2010

Research News and Research

Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

Flu season looking 'typical,' CDC says

Study finds inconsistencies in methods to identify CA-BSI infection in pediatric patients

Obesity can accelerate progression of acute lymphoblastic leukemia: Study

Smoking leads to epigenetic changes associated with cancer development: Research

Researchers find new surface adaptation mechanism of biofilm-forming pathogen

Researchers determine genetic structures of bacteria that cause Lyme disease

Researchers create experimental vaccine for Alzheimer's disease

IPS examines water, sanitation MDG Targets

Scientists identify molecular mechanism of muscle stem cell differentiation

Aetna, other insurers develop plans to help cut costs

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Administration's waivers of health law raise questions about 'mini-med' plans

IntegenX receives DTRA contract to develop ISS system for rapid detection of emerging pathogens

Research may offer new therapy targets for drug-resistant breast tumors

Are 'mini-med' plan waivers a good idea?

Anti-HER2 antibody-drug conjugate effective as first-line therapy for advanced breast cancer: Research

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

Opinions: Learning to live with malaria; U.S. food aid policy; foreign aid reform

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