Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Obesity drugs may help protect memory and cognitive abilities

Drugs used to treat obesity may also help protect the brain. In a review published in Science, researchers outline how a better understanding of these drugs' effects could lead to new treatments that protect memory and other important cognitive abilities.

6 Nov 2026

Women with Parkinson's have higher rates of Alzheimer's pathology

A new study is shedding light on how changes associated with different neurodegenerative diseases can overlap in the brain - and how that overlap may differ between women and men.

6 Nov 2026

Metal fumes, drinking habits and dementia: What a new study found

This study examines how workplace chemicals and lifestyle habits may influence Lewy body dementia risk, revealing potential sex differences in exposure effects.

6 Nov 2026

Graded physical activity prescriptions improve functional outcomes in psychiatry

Most of us have heard the advice so often that it has worn smooth, like a stone in a river: get some exercise. A new peer-reviewed Viewpoint in Brain Health, drawing on randomized trials, meta-analyses, and cohort studies, argues that this familiar sentence has been doing the wrong job.

5 Nov 2026

Modified zinc finger scaffold suppresses microglial activation in mouse brain

A KAIST-led research team has found that a protein involved in gene regulation can suppress the harmful aggregation of amyloid-beta, a peptide associated with Alzheimer's disease. The approach also reduced the toxicity of protein aggregates that had already formed.

5 Nov 2026

Tau spreads more rapidly in early-onset Alzheimer's disease

Patients with early-onset Alzheimer's disease, whose symptoms start before age 65, have more extensive deposits of tau, a hallmark protein of the condition, compared with patients whose symptoms start at 65-plus, a new study found.

5 Nov 2026

Brain scans reveal clues to Alzheimer's risk years before memory loss begins

Inside the brains of some cognitively normal adults, firing patterns were able to foretell Alzheimer's disease years before the onset of memory loss or the accumulation of plaques and tangles, according to new Stanford Medicine-led research.

5 Nov 2026

Targeting brain protein may help treat MEF2C-related neurological disorders

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study.

4 Nov 2026

Longer reproductive lifespan and hormonal history may influence brain vascular health

A longer reproductive lifespan and a history of using birth control pills or menopausal hormone therapy were associated with certain signs of blood vessel health in the brain, according to a study published November 4, 2026, in Neurology, the medical journal of the American Academy of Neurology.

4 Nov 2026

Novel treatment clears dementia-linked proteins from the waking brain

The brain's own clearance mechanisms are most active during sleep. Researchers have now shown that this natural clearance process can also be enhanced while people are awake.

4 Nov 2026

Eating peanuts every day may change your brains insulin response

The study finds that unsalted peanuts may enhance brain insulin responsiveness, providing new insights into dietary influences on cognitive health in aging.

4 Nov 2026

Study identifies molecular links between menopause and brain aging

Researchers at UC Santa Barbara, UC San Francisco and international collaborators are uncovering the cascade of molecular events that happen when women undergo menopause, a time of life marked by endocrine changes and symptoms like hot flashes, brain fog and sleep disturbances.

2 Nov 2026

Mount Sinai receives NIH grant to study advanced MRI methods for locating seizures

Researchers at the Icahn School of Medicine at Mount Sinai have received more than $3 million from the National Institutes of Health (NIH) for a five-year study of advanced magnetic resonance imaging (MRI) methods that may help locate seizure-causing brain regions in people with drug-resistant epilepsy.

2 Nov 2026

Skin organoids reveal how herpes simplex virus spreads between cells

Researchers at the Max Delbrück Center and University Medical Center Hamburg-Eppendorf have traced in skin organoids, how herpes simplex virus 1 infection progresses among neighboring skin cells, deepening our understanding.

30 Oct 2026

Mayo Clinic enters new medical era with precure research

Mayo Clinic researchers are uncovering the earliest shifts in disease biology - long before symptoms appear - revealing how disease takes root and opening new possibilities to identify, predict and potentially prevent disease before symptoms develop.

30 Oct 2026

Gut microbial catalog reveals systemic inflammation drivers in spinal injury

Scientists exploring the links between a spinal cord injury, inflammation and immune function have turned their attention to a genome-level analysis of the gut microbial community, with early study results offering hints at potential new approaches to aid healing.

30 Oct 2026

New metabolic score may help predict healthy aging and disease risk

Studies conducted in various countries indicate that approximately 60% of people over the age of 65 currently live with two or more chronic conditions simultaneously.

29 Oct 2026

Large genetic study uncovers new risk factors for Alzheimer's

A large-scale international study, led by Ole Andreassen at University of Oslo and Oslo University Hospital, in collaboration with international consortium, offers new insights for understanding the disease and developing future treatments.

29 Oct 2026

New Yale initiative explores the role of inflammation in disease

Yale School of Medicine (YSM) was awarded a $10 million grant from the Blavatnik Family Foundation (BFF) to launch a new research initiative in the field of inflammation science.

29 Oct 2026

Limited app use adds a twist to a nurse-led dementia risk trial

A cluster-randomized trial involving 403 Australian adults aged 45–65 found that a 12-month nurse-led behavioral intervention supported by a mobile app modestly improved estimated dementia risk scores compared with brief counseling and usual care. The study found no significant improvements in cognitive performance or other secondary outcomes, leaving its long-term effects on dementia prevention uncertain.

28 Oct 2026