Amelogenesis Imperfecta News and Research

RSS

Scientists discover tiny protein region that shapes tooth enamel

Tooth enamel looks simple from the outside and consists of a hard, smooth surface built to withstand years of wear.

11 Sep 2026

Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

9 Jul 2026

Genetic research links KDF1 mutation to impaired dental epithelial organization

Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay. However, enamel cannot regenerate once damaged. Inherited disorders, such as amelogenesis imperfecta, disrupt enamel formation during development, leaving affected individuals with fragile, discolored, and decay-prone teeth.

30 Jun 2026

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

Oldest evidence yet of a human hereditary genetic disorder found

The discovery of what is believed to be the oldest evidence yet found of a human hereditary genetic disorder has been announced by researchers at the Hebrew University of Jerusalem.

28 Jun 2004