Atomoxetine News and Research

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Oral AD109 improves sleep apnea severity but tolerability remains a challenge

AD109, an investigational once-daily oral combination of aroxybutynin and atomoxetine, significantly improved airway obstruction and oxygenation in adults with mild-to-severe obstructive sleep apnea who could not use PAP therapy. However, symptom improvements did not clearly differ from placebo, and about one in five AD109 recipients discontinued treatment due to adverse events.

21 May 2026

Once-nightly oral pill helps control obstructive sleep apnea

A once-nightly oral pill helped control obstructive sleep apnea in a large, phase 3 clinical trial presented at the 2026 ATS International Conference.

18 May 2026

Boosting noradrenaline during learning makes the brain link memories more broadly, study finds

A randomized placebo controlled experiment shows that increasing noradrenaline during learning does not improve basic memory accuracy but increases the spread of associations across the hippocampal cognitive map. This broader neural linking leads to greater overgeneralization errors days later, suggesting that noradrenergic arousal can reshape how related memories become interconnected.

16 Mar 2026

ADHD medication lowers risk of substance misuse and accidents

ADHD medications are linked to reduced risks of dangerous outcomes, including substance misuse and criminality, supporting their use in treatment strategies.

18 Aug 2025

ADHD medications show minimal impact on heart health in large study

A new study led by the University of Southampton has found that medications for ADHD have overall small effects on blood pressure and heart rate after weeks or a few months of use.

7 Apr 2025

ADHD prescriptions in England surge by 18% since the pandemic

Prescriptions for attention deficit hyperactivity disorder (ADHD) in England have risen 18% year on year since the pandemic.

12 Mar 2025

Can chili peppers improve ADHD symptoms? Scientists explore their gut-brain connection

Chili peppers may influence ADHD symptoms by modulating the gut microbiome, with capsaicin, vitamin C, and omega-3 fatty acids showing potential effects on neurotransmitters and inflammation. However, clinical trials are needed to confirm their efficacy.

20 Feb 2025

Comprehensive study highlights effectiveness and limitations of ADHD treatments in adults

Findings indicate stimulants and atomoxetine effectively reduce ADHD symptoms, though non-pharmacological therapies show potential for long-term efficacy.

20 Dec 2024

Pandemic stress leads to surge in ADHD diagnoses and medication use in Finland

Study reveals a significant rise in ADHD diagnoses and medication use in Finland during the COVID-19 pandemic, highlighting the pandemic's impact on mental health recognition, especially among young women and older adults.

3 Jul 2024

Does your ADHD medication increase your risk of glaucoma?

The risks of glaucoma among users of ADHD medications.

8 May 2024

ADHD medication proves most effective in treating symptoms, new study finds

A comprehensive overview of treatment options available for ADHD for children and adolescent individuals.

27 Mar 2024

Study reveals ADHD medication reduces psychiatric hospitalizations and work disability

Study highlights the benefits and potential risks of ADHD medication, revealing that stimulants like amphetamines and methylphenidate reduce the risk of psychiatric hospitalization and improve long-term employment outcomes, though concerns about adverse effects such as increased heart rate and potential for triggering psychosis or mania remain.

24 Mar 2024

New research explores the unique effects of ADHD medications on Drosophila brain cells

The effect of two drugs used for the treatment of attention-deficit/hyperactivity disorder.

15 Nov 2023

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

There is "good evidence" that drugs to treat attention deficit hyperactivity disorder (ADHD) might also successfully treat key aspects of Alzheimer's disease, finds a pooled data analysis of the available research, published online in the Journal of Neurology Neurosurgery & Psychiatry.

6 Jul 2022

Study points toward an alternative drug strategy to stall Alzheimer’s neurodegeneration

Boosting levels of the neurotransmitter norepinephrine with atomoxetine, a repurposed ADHD medication, may be able to stall neurodegeneration in people with early signs of Alzheimer's disease, a study conducted at Emory Brain Health Center suggests.

22 Dec 2021

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care

11 Jun 2021

Children diagnosed with ADHD less likely to take medication consistently

Children diagnosed with ADHD inconsistently take their prescribed medication, going without treatment 40 per cent of the time, a new study has found.

3 Feb 2020

First device-based, non-drug therapy for treating ADHD in children

Deciding how to treat attention deficit hyperactivity disorder in children can be a difficult decision for parents. Stimulants, such as Adderall and Ritalin, are the most commonly prescribed ADHD treatments - and are considered to be the most effective.

8 Nov 2019

Short- and long-term ADHD medication users have lower risk of STIs, study finds

Attention-deficit/hyperactivity disorder (ADHD) increases the risk of subsequent sexually transmitted infections (STIs) among adolescent and young adult populations by about three times, reports a study published in the January 2018 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.

3 Jan 2018

ADHD medicines linked to lower risk for substance use problems in adolescents, adults

The use of medication to treat attention deficit hyperactivity disorder is linked to significantly lower risk for substance use problems in adolescents and adults with ADHD, according to a study led by researchers at Indiana University.

12 Jul 2017