Diabetes Insipidus News and Research

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Diabetes insipidus (DI) is a rare disease that causes frequent urination. The large volume of urine is diluted, mostly water. To make up for lost water, a person with DI may feel the need to drink large amounts and is likely to urinate frequently, even at night, which can disrupt sleep and, on occasion, cause bedwetting. Because of the excretion of abnormally large volumes of dilute urine, people with DI may quickly become dehydrated if they do not drink enough water. Children with DI may be irritable or listless and may have fever, vomiting, or diarrhea. Milder forms of DI can be managed by drinking enough water, usually between 2 and 2.5 liters a day. DI severe enough to endanger a person’s health is rare.

Targeted therapy treats mixed histiocytosis following multiple skull relapses

Mixed histiocytosis (Langerhans cell histiocytosis [LCH] / Erdheim-Chester disease [ECD]) developing after treatment for initial skull LCH is not well recognized.

13 Apr 2026

Study finds gaps in preventive care for women with diabetes

Physicians are less likely to provide preventive care such as conception counseling and some cancer screenings to women with diabetes than they do for women without the disease, a UCLA-led study suggests.

3 Apr 2026

A single drug stabilizes nearly all mutations of key kidney protein

A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilize nearly all mutated versions of a human protein, regardless of where the mutation is in the sequence.

23 Sep 2025

Chronic hyponatremia causes anxiety-like behaviors by disrupting brain chemistry

Hyponatremia, or low blood sodium concentration, is typically viewed as a symptomless condition-until recently.

12 Jun 2025

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Low serum sodium concentrations in blood are called hyponatremia, a prevalent clinical electrolyte disorder.

18 Sep 2024

Study explores the effects of hyperosmotic stress on microglial cells

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats.

4 Sep 2024

Chronic underhydration linked to major health risks, study finds

Chronic underhydration has been linked to severe long-term health issues, including heart disease, diabetes, and kidney dysfunction, underscoring the need for increased hydration awareness and intervention strategies.

27 Feb 2024

Rare case of COVID-19 vaccine-induced hypophysitis in a woman with central diabetes insipidus manifestations

A new study to be published in the Therapies journal aimed to analyze a rare case of hypophysitis caused by pituitary stalk thickening three days following the administration of the SARS-CoV-2 vaccine.

11 Oct 2022

Doctoral thesis focuses on the role of oxidative stress in Wolfram syndrome and hypothermia

In the Faculty of Medicine at the University of Tartu, the first animal testings were conducted using antioxidant peptides designed and synthesized by scientists in Tartu, which may reduce oxidative stress.

29 May 2019

New test method offers more reliable diagnosis of diabetes insipidus

When people produce excessive amounts of urine - more than three litres each day in adults is considered too much - doctors often find it difficult to establish a diagnosis under certain circumstances.

7 Aug 2018

Brain's quality control process holds clues to obesity's roots

Deep in the middle of our heads lies a tiny nub of nerve cells that play a key role in how hungry we feel, how much we eat, and how much weight we gain. Around the clock, they produce a "grandfather" form of several hormones that help us regulate these crucial functions.

20 Feb 2018

Discovery reveals new role for endoplasmic reticulum-associated degradation

The discovery of a puddle of mouse urine seems like a strange scientific "eureka" moment. However, for one team of researchers, that's exactly what led to a new discovery.

20 Sep 2017

People with reduced oxytocin levels perform worse on empathy tasks, new research shows

People suffering medical conditions causing low levels of oxytocin perform worse on empathy tasks, according to new research presented today at the Society for Endocrinology annual conference in Brighton.

7 Nov 2016

Endocrine Society issues new guidelines on hypopituitarism

The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body's natural patterns as possible.

13 Oct 2016

Continuous glucose monitoring (CGM) mobile communications: an interview with Jorge Valdes

Type 1 diabetes is a complex condition to manage. It requires continuous, around the clock monitoring of blood glucose levels, which change repeatedly throughout the day and night.

7 Dec 2014

Researchers discover new molecular mechanism to prevent edema formation

Researchers of the Max Delbr-ck Center for Molecular Medicine and the Leibniz Institute of Molecular Pharmacology in Berlin-Buch, Germany, have now detected a substance that can prevent the accumulation of fluid in body tissue and thus edema formation.

8 Apr 2013

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

Diabetes alone may cost a sixth of total NHS budget by 2035: Report

A new report warns that diabetes will cost the NHS more than a sixth of its entire budget by 2035. The disease accounts for 10 per cent (£9.8 billion) of NHS spending, but this is projected to rise to £16.9 billion over the next 25 years, or 17 per cent of the health service's funds. There are around 3.8 million people living with diabetes in the UK and this is expected to increase to 6.25 million in just over two decades.

26 Apr 2012

Blood test to diagnose depression in adolescents

Researchers have developed a blood test that can diagnose depression in teens, a step they hope will lead to a better way to identify the disorder in young people. At present diagnosing depression depends entirely on a patient's willingness to report symptoms. For teens, the diagnosis is particularly challenging, given the natural emotional ups and downs of adolescence.

18 Apr 2012

Thousands of diabetes-related deaths could be avoided with better care: UK Report

According to a new report up to 24,000 diabetes-related deaths could be avoided in England each year, if patients and doctors better managed the condition. This is the first-ever audit of patient deaths from diabetes. It says that basic health checks, a good diet and regular medication could prevent most of the deaths.

15 Dec 2011