Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New framework maps the complex link between psychological status and cardiovascular health

CVD remains the leading cause of death worldwide, while the global burden of mental disorders continues to rise.

28 Sep 2026

Continuous glucose monitors show strong survival benefits for type 2 diabetes patients

People with type 2 diabetes (T2D) on basal insulin, starting continuous glucose monitoring (CGM) had a 44% lower risk of dying from any cause after one year compared with those who did not use CGM, with the risk being 35% lower after two years, according to an analysis of patient data being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

28 Sep 2026

New study tracks rising heart and kidney risks in people with type 2 diabetes

The risk of developing chronic kidney disease (CKD) or heart failure (HF), or dying, following a type 2 diabetes (T2D) diagnosis increases substantially over time, according to new research being presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

27 Sep 2026

Why one gut microbe is attracting attention in heart failure research

Researchers found that chronic systolic heart failure caused by nonischemic cardiomyopathy was associated with reduced gut microbial diversity, depletion of Bifidobacterium, and lower microbial short-chain fatty acid production potential. Higher Bifidobacterium abundance and higher circulating indole-3-propionic acid levels were associated with milder disease and clinical improvement, although the findings do not establish causality.

27 Sep 2026

Heated tobacco users had more hypertension, but the story is not that simple

A large Japanese real-world cohort study found that current heated tobacco product users had a higher risk of developing hypertension than never-smokers in the primary adjusted analysis. However, the association weakened in several sensitivity analyses, and the observational study could not separate the effects of current heated tobacco use from previous cigarette exposure.

27 Sep 2026

Study identifies shared pathway driving cardiac fibrosis

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart.

24 Sep 2026

As GLP-1 drugs become more complex, their effects on the heart are getting harder to predict

A brief report reviews emerging GLP-1 receptor co-agonists that also target GIPR, GCGR, and other receptors, examining their metabolic benefits alongside known and predicted cardiac effects. The authors highlight substantial species differences, warning that mouse heart studies may fail to predict responses in human cardiac tissue and that many proposed cardiac effects still require direct testing.

24 Sep 2026

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

In a large UK Biobank study, higher levels of the chronic inflammation marker GlycA were associated with smaller heart chambers, thicker heart walls, impaired diastolic function, reduced stroke volume, and a 43% higher risk of major adverse cardiovascular events in the highest versus lowest GlycA group. Genetic susceptibility also modified the associations between environmental exposures, inflammation, and cardiovascular risk, while inflammatory proteins in the IL-1, TNF, and IL-6 pathways statistically mediated several of these associations.

23 Sep 2026

Wildfire smoke may be more harmful than other air pollution, two Mount Sinai studies find

As climate change drives more frequent and intense wildfires, researchers at the Icahn School of Medicine at Mount Sinai have published two large-scale studies showing that wildfire smoke may pose greater health risks than other sources of air pollution, with higher risks of hospitalization for cardiovascular and respiratory disease and poorer survival among patients with lung cancer.

18 Sep 2026

Chronic stress and inflammation cause silent structural heart damage

Chronic stress from people's everyday lives may be causing lasting structural changes to the heart, harming health and reducing life expectancy.

18 Sep 2026

Wildfire smoke poses greater health risks than other pollution

17 Sep 2026

Study finds gender differences in active medical treatment

New research from the University of St Andrews has found that women are less like than men with the same medical condition to be offered active management such as surgery, a stent or a strong painkiller.

16 Sep 2026

Why frailty and heart health may be more closely connected than we thought

A narrative review proposes cardiovascular frailty as a distinct phenotype that brings together blood pressure regulation, vascular aging, oxi-inflammaging, and clinical frailty deficits. The authors argue that a validated cardiovascular frailty index could support earlier detection and personalized care, although longitudinal studies are needed before the concept can be used clinically.

15 Sep 2026

Cardiovascular disease surpasses cancer as top killer of Hispanic populations in the U.S.

Cardiovascular disease has surpassed cancer as the leading cause of death among Hispanic adults in the U.S., driven by rising rates of obesity, diabetes, high blood pressure and other risk factors that often begin earlier in life for Hispanic people.

15 Sep 2026

Eye scans detect signs of atrial fibrillation years before diagnosis

People with atrial fibrillation have signs of the condition in the retinas of their eyes that can be detected as early as four years before diagnosis, finds a new study led by University College London (UCL) and Moorfields researchers.

14 Sep 2026

Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected

In a US multicenter electronic health record study, researchers compared tirzepatide with semaglutide in adults with asthma and type 2 diabetes, matching 8,176 patients in each treatment group. Asthma exacerbation risk was similar between treatments, while tirzepatide was associated with a lower likelihood of receiving a short-acting beta-agonist prescription.

14 Sep 2026

Nighttime light exposure may alter heart structure and function

Exposure to light during the nighttime is linked to important and potentially harmful changes to the structure and function of the heart, according to a study of more than 11,000 people published in the European Heart Journal today (Thursday).

10 Sep 2026

Hormone therapy during menopause transition associated with lower heart disease risk

A study led by Virginia Commonwealth University and the University of Pittsburgh provides pivotal insights into one of the most debated questions in women's health: how does hormone therapy for menopause symptoms affect cardiovascular disease risk when used in peri- or early postmenopause?

8 Sep 2026

Leicester's cardiovascular research hub shines spotlight on life-saving innovations

The latest medical innovations in cardiovascular research have been showcased by the British Heat Foundation Leicester Centre of Research Excellence.

8 Sep 2026

Mitochondrial stress triggers long-term protection against heart damage

Mitochondria are popularly known as the "powerhouse of the cell," but these cellular structures do so much more-including acting as signaling hubs.

4 Sep 2026

Heart Failure News and Research

Further Reading

New framework maps the complex link between psychological status and cardiovascular health

Continuous glucose monitors show strong survival benefits for type 2 diabetes patients

New study tracks rising heart and kidney risks in people with type 2 diabetes

Why one gut microbe is attracting attention in heart failure research

Heated tobacco users had more hypertension, but the story is not that simple

Study identifies shared pathway driving cardiac fibrosis

As GLP-1 drugs become more complex, their effects on the heart are getting harder to predict

What links smoking, body fat, mental health, genes, and heart risk? Inflammation may be part of the answer

Wildfire smoke may be more harmful than other air pollution, two Mount Sinai studies find

Chronic stress and inflammation cause silent structural heart damage

Wildfire smoke poses greater health risks than other pollution

Study finds gender differences in active medical treatment

Why frailty and heart health may be more closely connected than we thought

Cardiovascular disease surpasses cancer as top killer of Hispanic populations in the U.S.

Eye scans detect signs of atrial fibrillation years before diagnosis

Tirzepatide vs semaglutide for asthma: the difference was smaller than researchers expected

Nighttime light exposure may alter heart structure and function

Hormone therapy during menopause transition associated with lower heart disease risk

Leicester's cardiovascular research hub shines spotlight on life-saving innovations

Mitochondrial stress triggers long-term protection against heart damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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