Maxillofacial News and Research

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NIH funds national center to advance root canal alternatives

Which would you rather have: a root canal or a pulpotomy? Even if you're not familiar with a pulpotomy, you might be inclined to learn more.

23 Sep 2026

Autonomous robotic system improves precision in tooth autotransplantation surgery

Tooth autotransplantation is a recognized treatment option for replacing missing teeth, particularly in young patients, as it preserves natural tooth function, supports continued jaw development, and eliminates the need for dental implants.

17 Aug 2026

European project receives €15 million to study phage-based therapies

Bacteria are becoming increasingly resistant to antibiotics. One alternative is treatment with viruses that exclusively infect bacteria, known as phages.

25 Jun 2026

Researchers uncover key mechanism driving chronic Sjögren disease

Sjögren disease, an autoimmune disease characterized by dry mouth and dry eyes, may reduce patients’ quality of life.

24 Jun 2026

Robotics and augmented reality improve precision in complex jaw surgery

RAMRS consists of two modules. The first, robot‑assisted osteotomy, uses an optical tracking system and a collaborative robotic arm to guide the bone saw. A hand‑eye calibration procedure determines the exact pose of the robot's end‑effector relative to a tracking marker.

17 Jun 2026

Mid-career surgeons show highest likelihood of leaving clinical practice

Surgeons are an integral part of the health care system, supplying critical and urgent care in nearly every field of medicine.

21 May 2026

Periodontal bacteria trigger bone density reduction via the gut

Periodontitis, a chronic inflammatory disease of the gums, affects hundreds of millions of people worldwide and is increasingly linked to systemic disorders beyond the oral cavity.

4 Mar 2026

NIH’s continued investment fuels TMJ pain research

Chronic pain is one of the most common health conditions worldwide. Back pain is the most frequently reported type, followed closely by head and face pain linked to the jaw joint, in the form of temporomandibular joint (TMJ) disorder.

27 Feb 2026

Oral cancer pain and opioid tolerance share a common EGFR mechanism

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective, according to new research published in Science Signaling.

29 Jan 2026

Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

The interaction between genetics and tissue environment shapes how individual teeth form in different regions of the jaw.

12 Dec 2025

New NIH grants fuel research in oral cancer treatment and pain relief

Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

7 Nov 2025

Over-the-counter pain relievers outperform opioids after wisdom tooth extraction

Over-the-counter pain medications work as well or better than opioids after wisdom tooth extraction for both men and women, according to a Rutgers Health-led follow-up to a landmark paper on comparative pain relief.

6 Nov 2025

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.

30 Sep 2025

New insights into bone remodeling process in orthodontic tooth movement under hypoxia

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan.

25 Aug 2025

Oral health function linked to markers of lifestyle-related diseases in older adults

The term 'oral health' refers to the health of the mouth, teeth, gums, and other related structures, and it is closely linked with our well-being and quality of life.

12 Jul 2025

Next-generation hydrogel supports regeneration of salivary gland-like tissue

Salivary glands play an essential role in protecting oral health by secreting saliva to aid in digestion, speech, and immunity.

30 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Gum disease bacterium linked to increased risk of atrial fibrillation

Tempted to skip the floss? Your heart might thank you if you don't. A new study from Hiroshima University (HU) finds that the gum disease bacterium Porphyromonas gingivalis (P. gingivalis) can slip into the bloodstream and infiltrate the heart.

10 May 2025

New consensus on clear aligner treatment aims to improve orthodontic outcomes

Malocclusion affects nearly half of the global population, impacting oral function and aesthetics. Clear aligners have gained popularity due to their discreet appearance and ease of use, but their effectiveness varies depending on the type of tooth movement required.

7 May 2025

Anti-inflammatory drug can prevent and alleviate periodontal tissue damage

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent and alleviate periodontal tissue damage.

28 Apr 2025