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Triple combination therapy trial for HR+/HER2− breast cancer halts early due to toxicity concerns

HR+/HER2− breast cancer constitutes approximately 65–75% of all breast cancer cases worldwide. Although CDK4/6 inhibitors have substantially extended progression-free survival (PFS), up to 60% of patients derive no clinical benefit from these agents, underscoring the urgent need for more effective therapeutic strategies.

28 Sep 2026

New framework maps the complex link between psychological status and cardiovascular health

CVD remains the leading cause of death worldwide, while the global burden of mental disorders continues to rise.

28 Sep 2026

Baseline liver fibrosis severity predicts treatment response in patients with HBeAg-positive CHB

The impact of baseline liver fibrosis severity on the effectiveness of pegylated interferon (Peg-IFN) combined with nucleos(t)ide analogs (NAs) in the treatment of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) has not been fully clarified.

23 Sep 2026

Siemens Healthineers brings new CN-3000 and CN-6000 hemostasis testing systems to US labs to help manage growing workloads

Siemens Healthineers announced today that the automated hemostasis analyzers for mid- and high-volume laboratories are now available for patient testing in the United States.

From Siemens Healthineers 17 Sep 2026

Study uncovers how interferon-alpha treats rare blood cancers

The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem cells to become shorter-lived white blood cells, according to a study by Weill Cornell Medicine investigators.

15 Sep 2026

Ris-Rez improves survival in patients with relapsed small-cell lung cancer

Results from the randomized Phase III ARTEMIS-008 trial show that risvutatug rezetecan (Ris-Rez), a B7-H3-directed antibody-drug conjugate, significantly improved overall survival compared with topotecan in patients with relapsed small-cell lung cancer (SCLC) whose disease progressed on or after platinum-based chemotherapy.

14 Sep 2026

McMaster researchers discover molecular switch causing dangerous blood clots

A cross-campus team of McMaster University researchers has identified why some patients develop dangerous blood clots after exposure to a common blood thinner – and a potential way to prevent it.

11 Sep 2026

Retinal immune cell gateway may unlock targeted uveitis treatments

As part of an effort to understand the molecules and mechanisms that regulate transendothelial migration in different vascular beds of the body, researchers focused on the blood vessels of the retina, part of the blood-brain barrier.

8 Sep 2026

Optimized EAP regimen delivers outstanding mobilization effects in multiple myeloma and lymphoma patients

This prospective, multicenter phase II study was conducted across 12 medical institutions in China and registered at ClinicalTrials.gov (NCT05536154).

27 Aug 2026

Mitochondrial transplantation helps repair donor organs during machine perfusion

Transplant medicine still depends on a limited supply of donor organs, while many retrieved grafts are discarded because ischemia, cold storage, and reperfusion can rapidly damage their cells.

25 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

AI identifies key gene driving aging in blood stem cells

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell.

24 Aug 2026

Tick-borne alpha-gal syndrome poses potential risks during blood transfusions

A new multi-institute study led by researchers at Dartmouth Health and Geisel School of Medicine at Dartmouth suggests that alpha-gal syndrome, the tick-borne disease that can result in a chronic allergy to meat and animal byproducts, also may complicate certain patients' ability to safely receive a blood plasma or platelet transfusion.

24 Aug 2026

Combined bio-histological score prevents overtreatment in liver transplant patients

Long‑term outcomes after liver transplantation remain hampered by complications linked to intensive immunosuppression—infections, cardiovascular events, kidney dysfunction, and metabolic disorders affect 10% to 40% of recipients.

24 Aug 2026

Simple scheduling change can improve health and well-being of night-shift physicians

University of Missouri researchers have found that a simple scheduling change can improve the health and well-being of physicians working overnight shifts.

17 Aug 2026

Würzburg researchers discover alternative approach to preventing thrombosis

Glycoprotein VI, or GPVI for short, is a surface receptor found exclusively on platelets and their precursor cells, megakaryocytes in the bone marrow.

14 Aug 2026

Perilla oil may curb platelet reactivity and inflammatory signaling in smokers

An eight-week randomized trial found that daily perilla oil increased plasma and red-cell ALA, plasma EPA, and platelet closure time in healthy smokers. Perilla oil also reduced TNF-α and TBX21 gene expression, but it did not improve broader coagulation, lipid, endothelial, or postprandial markers.

3 Aug 2026

Perilla oil improves blood flow and reduces inflammation in healthy smokers

Cardiovascular disease (CVD) is among the leading causes of death worldwide. In South Korea, it is the second leading cause of death, and its incidence has continued to rise in recent years.

30 Jul 2026

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

28 Jul 2026

Heatwave exposure associated with accelerated biological aging in middle-aged and older adults

As global climate change intensifies, heatwaves are becoming more frequent, longer, and more severe, emerging as an important environmental stressor for human health.

28 Jul 2026

Platelet News and Research

Triple combination therapy trial for HR+/HER2− breast cancer halts early due to toxicity concerns

New framework maps the complex link between psychological status and cardiovascular health

Baseline liver fibrosis severity predicts treatment response in patients with HBeAg-positive CHB

Siemens Healthineers brings new CN-3000 and CN-6000 hemostasis testing systems to US labs to help manage growing workloads

Study uncovers how interferon-alpha treats rare blood cancers

Ris-Rez improves survival in patients with relapsed small-cell lung cancer

McMaster researchers discover molecular switch causing dangerous blood clots

Retinal immune cell gateway may unlock targeted uveitis treatments

Optimized EAP regimen delivers outstanding mobilization effects in multiple myeloma and lymphoma patients

Mitochondrial transplantation helps repair donor organs during machine perfusion

What decades of wine research can, and cannot, tell us about health

AI identifies key gene driving aging in blood stem cells

Tick-borne alpha-gal syndrome poses potential risks during blood transfusions

Combined bio-histological score prevents overtreatment in liver transplant patients

Simple scheduling change can improve health and well-being of night-shift physicians

Würzburg researchers discover alternative approach to preventing thrombosis

Perilla oil may curb platelet reactivity and inflammatory signaling in smokers

Perilla oil improves blood flow and reduces inflammation in healthy smokers

AI model predicts cancer diagnoses up to a year in advance using routine clinical data

Heatwave exposure associated with accelerated biological aging in middle-aged and older adults

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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